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Autophagy induces hair follicle stem cell activation and hair follicle regeneration by regulating glycolysis
BackgroundHair follicle stem cells (HFSCs) typically remain quiescent and are activated only during the transition from telogen to anagen to ensure...
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Tracking Follicle Cell Development
Somatic follicle cells are critical support cells for Drosophila oogenesis, as they provide signals and molecules needed to produce a mature egg....
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Local and systemic mechanisms that control the hair follicle stem cell niche
Hair follicles are essential appendages of the mammalian skin, as hair performs vital functions of protection, thermoregulation and sensation. Hair...
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PARP1-catalyzed PARylation of YY1 mediates endoplasmic reticulum stress in granulosa cells to determine primordial follicle activation
Although only a small number of primordial follicles are known to be selectively activated during female reproductive cycles, the mechanisms that...
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Progenitor-derived endothelin controls dermal sheath contraction for hair follicle regression
Substantial follicle remodelling during the regression phase of the hair growth cycle is coordinated by the contraction of the dermal sheath smooth...
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Identification and analysis of key circRNAs in the mouse embryonic ovary provides insight into primordial follicle development
BackgroundCircRNAs are a class of noncoding RNAs with tissue- and development-specific expression characteristics. In many mammals, primordial...
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Cellular Heterogeneity Facilitates the Functional Differences Between Hair Follicle Dermal Sheath Cells and Dermal Papilla Cells: A New Classification System for Mesenchymal Cells within the Hair Follicle Niche
Mesenchymal stem cells (MSCs) are known for their self-renewal and multi-lineage differentiation potential, with these cells often being evaluated in...
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Ficoll density gradient sedimentation isolation of pelage hair follicle mesenchymal stem cells from adult mouse back skin: a novel method for hair follicle mesenchymal stem cells isolation
BackgroundHair follicle mesenchymal stem cells (HF-MSCs) have great potential for cell therapy. Traditional method to isolate whisker HF-MSC is...
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Adult hair follicle stem cells differentiate into neuronal cells in explanted rat intestinal tissue
Hair follicle stem cells (HFSCs) are adult stem cells located in the outer root sheath of the follicle bulge with high neural plasticity, which...
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SRSF1 regulates primordial follicle formation and number determination during meiotic prophase I
BackgroundOvarian folliculogenesis is a tightly regulated process leading to the formation of functional oocytes and involving successive quality...
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Phosphoproteomic analysis on ovarian follicles reveals the involvement of LSD1 phosphorylation in Chicken follicle selection
BackgroundFollicle selection in chickens refers to the process of selecting one follicle from a group of small yellow follicles (SY, 6–8 mm in...
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Simulated microgravity reduces quality of ovarian follicles and oocytes by disrupting communications of follicle cells
Ovarian follicles are the fundamental structures that support oocyte development, and communications between oocytes and follicle somatic cells are...
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P62 promotes FSH-induced antral follicle formation by directing degradation of ubiquitinated WT1
In females, the pathophysiological mechanism of poor ovarian response (POR) is not fully understood. Considering the expression level of p62 was...
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High expression circRALGPS2 in atretic follicle induces chicken granulosa cell apoptosis and autophagy via encoding a new protein
BackgroundThe reproductive performance of chickens mainly depends on the development of follicles. Abnormal follicle development can lead to...
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Construction of transcriptome atlas of white yak hair follicle during anagen and catagen using single-cell RNA sequencing
BackgroundAs the direct organ of villus, hair follicles have obvious seasonal cycles. The hair follicle cycle is orchestrated by multiple cell types...
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MiR-149-5p promotes β-catenin-induced goat hair follicle stem cell differentiation
The Yangtze River Delta white goat is a unique goat species that can produce superior-quality brush hair. The formation of superior-quality brush...
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GDF9His209GlnfsTer6/S428T and GDF9Q321X/S428T bi-allelic variants caused female subfertility with defective follicle enlargement
BackgroundAntral follicles consist of an oocyte cumulus complex surrounding by somatic cells, including mural granulosa cells as the inner layer and...
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Dental follicle cells show potential for treating Parkinson’s disease through dopaminergic-neuronogenic differentiation
Among all the adult stem cells, odontogenic stem cells inherit the characterization of neurogenic potential of their precursor ones–the cranial crest...
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Gene network analysis reveals candidate genes related with the hair follicle development in sheep
BackgroundMerino sheep are the most famous fine wool sheep in the world. They have high wool production and excellent wool quality and have attracted...
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Hair follicle-derived mesenchymal stem cells decrease alopecia areata mouse hair loss and reduce inflammation around the hair follicle
BackgroundAlopecia areata (AA) is a common autoimmune hair loss disease with increasing incidence. Corticosteroids are the most widely used for hair...
