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Platelet glycoprotein V spatio-temporally controls fibrin formation
The activation of platelets and coagulation at vascular injury sites is crucial for hemostasis but can promote thrombosis and inflammation in...
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The Effects of Injectable Platelet-Rich Fibrin and Advanced-Platelet Rich Fibrin on Gingival Fibroblast Cell Vitality, Proliferation, Differentiation
Background:Injectable Platelet Rich Fibrin (I-PRF) and Advanced-Platelet Rich Fibrin (A-PRF) are autologous materials derived from patients’ blood...
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Fibrin Coating Contributes to the Retention of the Endothelial Layer in Pulsating Flow
AbstractThe presence of a modifying coating based on extracellular matrix proteins on the inner surface of vascular prostheses is known to enhance...
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In-situ gelation of fibrin gel encapsulating platelet-rich plasma-derived exosomes promotes rotator cuff healing
Although platelet-rich plasma-derived exosomes (PRP-Exos) hold significant repair potential, their efficacy in treating rotator cuff tear (RCT)...
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Encapsulation of MSCs in PRP-Derived Fibrin Microbeads
Platelet-rich plasma (PRP) is a highly concentrated platelet-containing blood plasma that incorporates a significant amount of growth factors and...
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Combined computational modeling and experimental study of the biomechanical mechanisms of platelet-driven contraction of fibrin clots
While blood clot formation has been relatively well studied, little is known about the mechanisms underlying the subsequent structural and mechanical...
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Engineered Molecular Therapeutics Targeting Fibrin and the Coagulation System: a Biophysical Perspective
The coagulation cascade represents a sophisticated and highly choreographed series of molecular events taking place in the blood with important...
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Endothelial Cell Fibrin Gel Angiogenesis Bead Assay
The fibrin gel angiogenesis bead assay provides a controlled in vitro setting for observing endothelial angiogenic sprouting in response to modified...
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Fibrinogen and Fibrin
Fibrinogen is a large glycoprotein, synthesized primarily in the liver. With a normal plasma concentration of 1.5–3.5 g/L, fibrinogen is the most...
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Airway fibrin formation cascade in allergic asthma exacerbation: implications for inflammation and remodeling
BackgroundAirway remodeling in patients with asthma, which leads to a decline in pulmonary function, is likely the result of repeated exacerbations...
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A Simplified GBR Treatment and Evaluation of Posterior Seibert Class I Ridge Defects via Bio-collagen and Platelet-Rich Fibrin: A Retrospective Study
Background:Classical guided bone regeneration (GBR) treatments can achieve favorable clinical results for ridge defects. However, extensive bone...
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Effect of Hypochlorite- and Peroxide-Induced Oxidation of Fibrinogen on the Fibrin Structure
AbstractUsing the methods of dynamic and elastic light scattering and confocal laser scanning microscopy, the damage in the spatial fibrin structure...
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Maternal fibrinogen/fibrin degradation products to high density lipoprotein cholesterol ratio for predicting delivery of small and large for gestational age infants: a pilot study
BackgroundThe purpose of this pilot study was to investigate associations between fibrinogen/fibrin degradation products (FDP) to high density...
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Embryonic stem cells overexpressing high molecular weight FGF2 isoform enhance recovery of pre-ganglionic spinal root lesion in combination with fibrin biopolymer mediated root repair
BackgroundSpinal ventral root avulsion results in massive motoneuron degeneration with poor prognosis and high costs. In this study, we compared...
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Distinctive Roles of Wnt Signaling in Chondrogenic Differentiation of BMSCs under Coupling of Pressure and Platelet-Rich Fibrin
Background:Although newly formed constructs of feasible pressure-preadjusted bone marrow mesenchymal stem cells (BMSCs) and platelet-rich fibrin...
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Potential of a novel scaffold composed of human platelet lysate and fibrin for human corneal endothelial cells
Cell-based therapies have been emerged to find innovative solutions for corneal endothelial dysfunction. The aim of this study is to investigate the...
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Effects of platelet-rich fibrin on osteogenic differentiation of Schneiderian membrane derived mesenchymal stem cells and bone formation in maxillary sinus
BackgroundThe existence of mesenchymal stem cells (MSCs) in Schneiderian membrane has not been determined. The aim of this study is to investigate...
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Regenerative Potential of Platelet Rich Fibrin (PRF) in Socket Preservation in Comparison with Conventional Treatment Modalities: A Systematic Review and Meta-Analysis
BackgroundPlatelet rich fibrin (PRF) has shown great potential in osteogenesis; however, some studies still question utilizing it as a grafting...
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Effect of Leukocyte-Platelet Rich Fibrin (L-PRF) on Tissue Regeneration and Proliferation of Human Gingival Fibroblast Cells Cultured Using a Modified Method
Background:An in vitro study on rapid culturing method of human gingival fibroblast cells (HGFCs) was established to investigate the potential use...
