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Epigenomics Methods and Protocols
This detailed volume provides a comprehensive collection of protocols for epigenomic research, powering our ability to analyze epigenetic...
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Epigenomics in stress tolerance of plants under the climate change
BackgroundClimate change has had a tremendous impact on the environment in general as well as agricultural crops grown in these situations as time...
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Current Status and Future Strategy in Crop Improvement Using Epigenomics
Rapidly increasing population demands high yield of crops whereas the area under cultivation is decreasing with increased population. Also, the...
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Prospects and challenges of epigenomics in crop improvement
BackgroundThe advent of high-throughput epigenome map** techniques has ushered in a new era of multiomics with powerful tools now available to map...
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Computational Epigenomics and Epitranscriptomics
This volume details state-of-the-art computational methods designed to manage, analyze, and generally leverage epigenomic and epitranscriptomic data....
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The SEQC2 epigenomics quality control (EpiQC) study
BackgroundCytosine modifications in DNA such as 5-methylcytosine (5mC) underlie a broad range of developmental processes, maintain cellular lineage...
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Harnessing male germline epigenomics for the genetic improvement in cattle
Sperm is essential for successful artificial insemination in dairy cattle, and its quality can be influenced by both epigenetic modification and...
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Comparative epigenomics by machine learning approach for neuroblastoma
BackgroundNeuroblastoma (NB) is the second most common pediatric solid tumor. Because the number of genetic mutations found in tumors are small, even...
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Profiling the Epigenetic Landscape of the Spermatogonial Stem Cell—Part 1: Epigenomics Assays
Epigenomics encompasses analyses of a variety of different epigenetic parameters which, collectively, make up the epigenetic programming that...
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Comparative epigenomics reveals the impact of ruminant-specific regulatory elements on complex traits
BackgroundInsights into the genetic basis of complex traits and disease in both human and livestock species have been achieved over the past decade...
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AI in Genomics and Epigenomics
GeneticsGenetics is an important factor determining the predisposition to the development of many diseases and influencing the overall life...
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3DFAACTS-SNP: using regulatory T cell-specific epigenomics data to uncover candidate mechanisms of type 1 diabetes (T1D) risk
BackgroundGenome-wide association studies (GWAS) have enabled the discovery of single nucleotide polymorphisms (SNPs) that are significantly...
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Profiling the Epigenetic Landscape of the Spermatogonial Stem Cell: Part 2—Computational Analysis of Epigenomics Data
The final data-generation step of genome-wide profiling of any epigenetic parameter typically involves DNA deep sequencing which yields large...
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Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction
Single-cell multi-omics are powerful means to study cell-to-cell heterogeneity. Here, we present a single-tube, bisulfite-free method for the...
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