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In Vitro Generation of Human Cross-Presenting Type 1 Conventional Dendritic Cells (cDC1s) and Plasmacytoid Dendritic Cells (pDCs)
Dendritic cells (DCs) represent one of the most important immune cell subsets in preventing the host from pathogen invasion by promoting both innate...
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Human Purkinje cells outperform mouse Purkinje cells in dendritic complexity and computational capacity
Purkinje cells in the cerebellum are among the largest neurons in the brain and have been extensively investigated in rodents. However, their...
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Conventional type 1 dendritic cells (cDC1) in cancer immunity
Cancer immunotherapy, alone or in combination with conventional therapies, has revolutionized the landscape of antineoplastic treatments, with...
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Live Imaging of Golgi Outposts in Drosophila Dendritic Arbors
Neurons are polarized cells whose polarityPolarity and morphologyMorphology rely on the robust localization of cellular organellesOrganelles and...
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Electroacupuncture inhibits dendritic spine remodeling through the srGAP3-Rac1 signaling pathway in rats with SNL
Previous studies have shown that peripheral nerve injury can lead to abnormal dendritic spine remodeling in spinal dorsal horn neurons. Inhibition of...
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The BCL2 inhibitor venetoclax mediates anticancer effects through dendritic cell activation
BCL2 is an apoptosis-inhibitory oncoprotein that also possesses apoptosis-unrelated activities. Pharmacological BCL2 inhibitors have been developed...
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In Vitro Generation of Human Tolerogenic Monocyte-Derived Dendritic Cells
Human monocyte-derived dendritic cells (moDC) are commonly used as a research tool to investigate interactions between antigen-presenting cells and T...
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Dendritic cell therapy for neurospoagioma: Immunomodulation mediated by tumor vaccine
Neurospagioma, arising from different glial cells such as astrocytes, oligodendrocytes, and ependymal cells, stands as the prevalent intracranial...
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Dysregulated dendritic cells in sepsis: functional impairment and regulated cell death
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Studies have indicated that immune...
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In Vitro Generation of Human Dendritic Cell Subsets from CD34+ Cord Blood Progenitors
Dendritic cells (DCs) are professional antigen-presenting cells controlling the activation of T cells and thus regulating adaptive immune response...
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In Vitro Generation of Murine Bone Marrow–Derived Dendritic Cells
Dendritic cells (DCs) are mononuclear phagocytes of hematopoietic origin residing in lymphoid and nonlymphoid tissues. DCs are often referred as the...
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cGAS-STING pathway mediates activation of dendritic cell sensing of immunogenic tumors
Type I interferons (IFN-I) play pivotal roles in tumor therapy for three decades, underscoring the critical importance of maintaining the integrity...
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Neem leaf glycoprotein binding to Dectin-1 receptors on dendritic cell induces type-1 immunity through CARD9 mediated intracellular signal to NFκB
BackgroundA water-soluble ingredient of mature leaves of the tropical mahogany ‘Neem’ ( Azadirachta indica ), was identified as glycoprotein, thus...
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Mobilization and activation of tumor-infiltrating dendritic cells inhibits lymph node metastasis in intrahepatic cholangiocarcinoma
Lymph node metastasis (LNM) facilitates distant tumor colonization and leads to the high mortality in patients with intrahepatic cholangiocarcinoma...
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Differentiation, maturation, and collection of THP-1-derived dendritic cells based on a PEG hydrogel culture platform
PurposeDendritic cell (DC) is a spearhead responsible for immune response and surrounded by extracellular matrix in three-dimensional (3D) tissue....
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Lactobacilli Probiotics Modulate Antibacterial Response Gene Transcription of Dendritic Cells Challenged with LPS
Probiotics are beneficial bacteria that may modulate the immune response by altering the maturation and function of antigen-presenting cells, such as...
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Functional interdependence of the actin regulators CAP1 and cofilin1 in control of dendritic spine morphology
The vast majority of excitatory synapses are formed on small dendritic protrusions termed dendritic spines. Dendritic spines vary in size and density...
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Examining the Kinetics of Phagocytosis-Coupled Inflammasome Activation in Murine Bone Marrow-Derived Dendritic Cells
In the present chapter, we describe procedures to assess NLRP3 and NLRC4 inflammasome assembly by immunofluorescence microscopy or live cell imaging,...
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Modulation of Mouse Dendritic Cells In Vitro by Lactobacillus gasseri Postbiotic Proteins
Different lactobacilli are probiotics for their beneficial effects that confer to the host. Recently, some of these effects were associated with...
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