Search
Search Results
-
The oocyte cumulus complex regulates mouse sperm migration in the oviduct
As the time of ovulation draws near, mouse spermatozoa move out of the isthmic reservoir, which is a prerequisite for fertilization. However, the...
-
Heat shock interferes with the amino acid metabolism of bovine cumulus-oocyte complexes in vitro: a multistep analysis
By affecting the ovarian pool of follicles and their enclosed oocytes, heat stress has an impact on dairy cow fertility. This study aimed to...
-
Ameliorating Effect of Sodium Selenite on Developmental and Molecular Response of Bovine Cumulus-Oocyte Complexes Matured in Vitro Under Heat Stress Condition
Selenium (Se), an essential trace element, plays an important role in the antioxidative defense mechanism, and it has been proven to improve...
-
Diminished ovarian reserve causes adverse ART outcomes attributed to effects on oxygen metabolism function in cumulus cells
BackgroundDeclining oocyte quality in women with advanced age has been a major impediment to assisted reproductive treatments’ (ART) success rate....
-
Transcriptional profile of cumulus associated GJA1, PTX3, PRSS35, and SERPINE2 genes with oocytes and embryonic development in water buffalo
BackgroundIn the present study, the potential of different groups of cumulus-oocyte complexes (COC’s) for in vitro maturation (IVM) and embryonic...
-
Integrated analysis of the expression profiles of the lncRNA-miRNA-mRNA ceRNA network in granulosa and cumulus cells from yak ovaries
BackgroundGrowing oocytes acquire the ability to mature through two-way communication between gametes and surrounding somatic cumulus cells (CCs)....
-
IMD/ADM2 operates as a secretory factor that controls cumulus-oocyte complexes (COCs) conformation for oocytes in vitro maturation
During in vitro maturation (IVM), the compact structure of cumulus-oocyte complexes (COCs) is vital for oocyte competence acquisition....
-
Beauvericin alters the expression of genes coding for key proteins of the mitochondrial chain in ovine cumulus-oocyte complexes
Beauvericin (BEA) is a member of the enniatin family of mycotoxins which has received increasing interest because of frequent occurrence in food and...
-
Cumulus provides cloud-based data analysis for large-scale single-cell and single-nucleus RNA-seq
Massively parallel single-cell and single-nucleus RNA sequencing has opened the way to systematic tissue atlases in health and disease, but as the...
-
Effects of Ovarian Gonadotropin Stimulation under Conditions of Chronic Psychosocial Stress on the Quality of Murine Oocytes
AbstractChronic psychosocial stress can negatively affect the female reproductive system. Meanwhile, the effect of ovarian stimulation with...
-
Bioencapsulation of Oocytes and Granulosa Cells
A protocol for the encapsulation in sodium alginate of granulosa cells in primary culture and coculture of oocyte-cumulus complexes is reported....
-
Heat exposure impairs porcine oocyte quality with suppressed actin expression in cumulus cells and disrupted F-actin formation in transzonal projections
BackgroundTranszonal projections (TZPs) constitute a structural basis for the communication between the oocyte and its surrounding cumulus cells...
-
Analysis of the Ovarian Marker Genes Expression Revealed the Antagonistic Effects of Serotonin and Androstenedione on the Functional State of Mouse Granulosa Cells in Primary Culture
AbstractPrimary culture of granulosa cells is a prerequisite for a complete study of the normal functioning of the ovary and its pathologies. In this...
-
The Effect of Ethylmethylhydroxypyridine Succinate (Mexidol) on Oocyte Meiotic Maturation, Genome Integrity, and the Change in Gene Expression in Mouse Cumulus Cells under the Conditions of Systemic Immune Complex Damage
AbstractThe effect of ethylmethylhydroxypyridine succinate (HS, Mexidol) on oocyte meiotic maturation, level of DNA damage in follicular cells, and...
-
The role of zinc in follicular development
Follicles consist of specialized somatic cells that encase a single oocyte. Follicle development is a process regulated by a variety of endocrine,...
-
ISG15 suppresses ovulation and female fertility by ISGylating ADAMTS1
BackgroundISGylation is a post-translational protein modification that regulates many life activities, including immunomodulation, antiviral...
-
Corpora lutea affect in vitro maturation of bovine cumulus-oocyte complexes and embryonic development after fertilization with sex-sorted or conventional semen
Influence of both the presence of a corpus luteum on the ovary and semen sex-sorting on development following in vitro fertilization is not yet...
-
Ovulatory signal-triggered chromatin remodeling in ovarian granulosa cells by HDAC2 phosphorylation activation-mediated histone deacetylation
BackgroundEpigenetic reprogramming is involved in luteinizing hormone (LH)-induced ovulation; however, the underlying mechanisms are largely unknown.
...
-
SphK-produced S1P in somatic cells is indispensable for LH-EGFR signaling-induced mouse oocyte maturation
Germ cell division and differentiation require intimate contact and interaction with the surrounding somatic cells. Luteinizing hormone (LH) triggers...
-
Does the addition of follicular fluid in the in vitro maturation medium increase the oocyte maturation and embryo production in alpacas?
In alpacas ( Vicugna pacos ), the high cost of in vitro embryo production is also a consequence of the use of several substances in the culture medium....
