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X-chromosome inactivation in human iPSCs provides insight into X-regulated gene expression in autosomes
BackgroundVariation in X chromosome inactivation (XCI) in human-induced pluripotent stem cells (hiPSCs) can impact their ability to model biological...
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X‑chromosome loss rescues Sertoli cell maturation and spermatogenesis in Klinefelter syndrome
Klinefelter syndrome (47,XXY) causes infertility with a testicular histology comprising two types of Sertoli cell-only tubules, representing mature...
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XIST dampens X chromosome activity in a SPEN-dependent manner during early human development
XIST (X-inactive specific transcript) long noncoding RNA (lncRNA) is responsible for X chromosome inactivation (XCI) in placental mammals, yet it...
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Replication dynamics identifies the folding principles of the inactive X chromosome
Chromosome-wide late replication is an enigmatic hallmark of the inactive X chromosome (**). How it is established and what it represents remains...
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Biochemical Features of X or Y Chromosome-Bearing Spermatozoa for Sperm Sexing
AbstractThis review presents information on biochemical features of spermatozoa bearing X or Y chromosome, enabling production of a sperm fraction...
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Chromosome Numbers
The basic chromosome number in Panicum is x = 9, being uniform for the genus (Dubcovsky and Zuloaga 1991; Aliscioni et al. 2003). However, different...
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EpiTy**: analysis of epigenetic aberrations in parental imprinting and X-chromosome inactivation using RNA-seq
Human pluripotent stem cells (hPSCs) hold a central role in studying human development, in disease modeling and in regenerative medicine. These cells...
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Identification of skewed X chromosome inactivation using exome and transcriptome sequencing in patients with suspected rare genetic disease
BackgroundX-chromosome inactivation (XCI) is an epigenetic process that occurs during early development in mammalian females by randomly silencing...
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Chromosome Painting Using Chromosome-Specific BAC Clones
Chromosome painting (CP) refers to visualization of large chromosome regions, chromosome arms or entire chromosomes via fluorescence in situ...
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Constitutive heterochromatin propagation contributes to the X chromosome inactivation
Imprinted X chromosome inactivation (iXCI) balances the expression of X-linked genes in preimplantation embryos and extraembryonic tissues in...
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RNA polymerase II depletion from the inactive X chromosome territory is not mediated by physical compartmentalization
Subnuclear compartmentalization has been proposed to play an important role in gene regulation by segregating active and inactive parts of the genome...
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**st spatially amplifies SHARP/SPEN recruitment to balance chromosome-wide silencing and specificity to the X chromosome
Although thousands of long non-coding RNAs (lncRNAs) are encoded in mammalian genomes, their mechanisms of action are poorly understood, in part...
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Pre-implantation development of cattle embryos produced from fresh bull semen enriched for X- chromosome-bearing spermatozoa using a monoclonal antibody
Immunological approaches are gaining attention as a convenient and economical method for sex-sorting mammalian spermatozoa. A monoclonal antibody...
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Unraveling the role of **st in X chromosome inactivation: insights from rabbit model and deletion analysis of exons and repeat A
X chromosome inactivation (XCI) is a process that equalizes the expression of X-linked genes between males and females. It relies on **st ,...
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X-chromosome inactivation patterns depend on age and tissue but not conception method in humans
Female somatic X-chromosome inactivation (XCI) balances the X-linked transcriptional dosages between the sexes, randomly silencing the maternal or...
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Usefulness of the X-Chromosome on Forensic Science
In kinship analyses, as well as in other forensic studies, autosomal markers are, generally, the tool of choice. However, there are some more complex...
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Gene regulation in time and space during X-chromosome inactivation
X-chromosome inactivation (XCI) is the epigenetic mechanism that ensures X-linked dosage compensation between cells of females (XX karyotype) and...
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An Overview to the Index to Chromosome Numbers in Asteraceae Database: Revisiting Base Chromosome Numbers, Polyploidy, Descending Dysploidy, and Hybridization
A brief overview to the Index to Chromosome Numbers in Asteraceae database is provided. The database contains karyological information on Asteraceae...
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