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SHH induces macrophage oxidative phosphorylation and efferocytosis to promote scar formation
Excessive scar formation such as hypertrophic scars and keloids, resulting from trauma or surgical procedures, present a widespread concern for...
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Comprehensive analysis using DNA metabarcoding, SCAR marker based PCR assay, and HPLC unveils the adulteration in Brahmi herbal products
BackgroundBrahmi is one of the important nootropic botanicals, widely sold in the market, with the name “Brahmi’’ being used to describe both Bacopa...
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Development of sequence-characterized amplified region (SCAR) markers for accurate and differential identification of multienzyme-producing and non-enzymatic Aspergillus strains of industrial importance
Aspergillus strains are known to produce multiple enzymes of industrial importance. To screen Aspergillus isolates and select a strain with the...
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Assessing anthracnose resistance in common bean accessions: identification of resistance genes using SCAR markers against Colletotrichum lindemuthianum
Anthracnose caused by Colletotrichum lindemuthianum is an overwhelming disease causing substantial yield losses in common bean. Small and marginal...
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Human Umbilical Cord Mesenchymal Stem Cells Promote Anti-Inflammation and Angiogenesis by Targeting Macrophages in a Rat Uterine Scar Model
BackgroundHuman umbilical cord-derived mesenchymal stem cells (hUC-MSCs) have demonstrated efficacy in repairing uterine scars, although the...
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Genome-wide and sister chromatid-resolved profiling of protein occupancy in replicated chromatin with ChOR-seq and SCAR-seq
Elucidating the mechanisms underlying chromatin maintenance upon genome replication is critical for the understanding of how gene expression programs...
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Conversion of Existing AFLP Markers to SCAR Markers Linked to Globodera rostochiensis and Phytophthora infestans Resistance Could Be Performed Without Using Acrylamide Gel Electrophoresis
Marker-assisted selection (MAS) is more efficient with single locus marker methods than with the complex multi-locus AFLP TM system. Therefore, a...
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Bdellovibrio predation cycle characterized at nanometre-scale resolution with cryo-electron tomography
Bdellovibrio bacteriovorus is a microbial predator that offers promise as a living antibiotic for its ability to kill Gram-negative bacteria,...
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Microfluidic Device for High-Resolution Cytoskeleton Imaging and Washout Assays in Physcomitrium (Physcomitrella) patens
Visualizing cytoskeleton dynamics at high spatiotemporal resolution provides valuable insights into the way the dynamics change as well as its...
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Resolution-promoting autacoids demonstrate promising cardioprotective effects against heart diseases
AbstractChronic heart diseases have in common an unresolved inflammatory status. In atherosclerosis, myocarditis, myocardial infarction, or atrial...
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Human amniotic epithelial cell transplantation improves scar remodeling in a rabbit model of acute vocal fold injury: a pilot study
ObjectiveTo gain insight into the molecular mechanisms underlying the early stages of vocal fold extracellular matrix (ECM) remodeling after a...
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Macrophages modulate fibrosis during newt lens regeneration
BackgroundPrevious studies have suggested that macrophages are present during lens regeneration in newts, but their role in the process is yet to be...
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Phragmites-fire feedbacks: the influence of fire and disturbance-altered hydrology on the abundance of Phragmites australis
Historical land-use conversion and drainage may increase the risk of high intensity, soil-consuming fires in peatlands. Severe fires may degrade...
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Fat infiltration in the infarcted heart as a paradigm for ventricular arrhythmias
Infiltrating adipose tissue (inFAT) has been recently found to co-localize with scar in infarcted hearts and may contribute to ventricular...
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Cellular and molecular mechanisms of skin wound healing
Wound healing is a complex process that involves the coordinated actions of many different tissues and cell lineages. It requires tight orchestration...
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Inhibition and reversal of a TGF-β1 induced myofibroblast phenotype by adipose tissue-derived paracrine factors
BackgroundHypertrophic scarring results from myofibroblast differentiation and persistence during wound healing. Currently no effective treatment for...
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Polyphasic identification of surgacane root-knot nematodes from ten municipalities in São Paulo State, Brazil
Root-knot nematodes ( Meloidogyne spp.; RKN) are among the most destructive plant parasites in sugarcane. In Brazil, they are known to cause yield...
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Identification of SCAR markers linked to the Foc gene governing resistance to Fusarium oxysporum f. sp. cucumerinum in cucumber cv. SMR-18
Fusarium wilt, caused by Fusarium oxysporum f. sp. cucumerinum (FOC) is an important soil-borne disease of cucumber in several parts of the world. In...
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Harnessing metabolism of hepatic macrophages to aid liver regeneration
Liver regeneration is a dynamic and regulated process that involves inflammation, granulation, and tissue remodeling. Hepatic macrophages, abundantly...
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The development of species-specific AFLP-derived SCAR and SSCP markers to identify mantis shrimp species
Mantis shrimp has become commercially valuable in many countries, while the commercially aquaculture still unsuccessful. The stable supply of the...
