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Modeling fall armyworm resistance in Bt-maize areas during crop and off-seasons
Entomologists have often used computational modeling to study the dynamics of insects in agricultural landscapes. Recently, important issues such as...
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Within-Host Mathematical Models of Antibiotic Resistance
Mathematical models have been used to study the spread of infectious diseases from person to person. More recently studies are develo** within-host...
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Systematic Approach in Modeling the Biochemical Resistance Exhibited by the Plants Under Stress Conditions
Plants are often exposed to adverse environmental conditions that have a significant impact on crop yield. The incredible plant’s ability to adapt to...
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Effects of Various Heavy Metal Exposures on Insulin Resistance in Non-diabetic Populations: Interpretability Analysis from Machine Learning Modeling Perspective
Increasing and compelling evidence has been proved that heavy metal exposure is involved in the development of insulin resistance (IR). We trained an...
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Phenotypic Expression of Brown Rust Resistance in Wheat: Element Modeling
AbstractSurveys have been performed in order to analyze the phenotypic variation in wheat for brown rust resistance, to identify the factors causing...
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Spatio-temporal characterization of phenotypic resistance in malaria vector species
BackgroundMalaria, a deadly disease caused by Plasmodium protozoa parasite and transmitted through bites of infected female Anopheles mosquitoes,...
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Application of CRISPR for Plant-Mediated Resistance
Clustered regularly interspaced short palindromic repeats (CRISPR) and associated protein 9 (CRISPR-Cas9) have emerged as an efficient genome editing...
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Modeling the limits of detection for antimicrobial resistance genes in agri-food samples: a comparative analysis of bioinformatics tools
BackgroundAlthough the spread of antimicrobial resistance (AMR) through food and its production poses a significant concern, there is limited...
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Insect Resistance
Studies to-date have shown the availability of enough genetic diversity in the wheat genetic resources (land races, wild relatives, cultivars, etc.)...
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The management of grapevine downy mildew: from anti-resistance strategies to innovative approaches for fungicide resistance monitoring
Efficient grapevine downy mildew control necessitates the implementation of anti-resistance strategies to ensure the ongoing efficacy of available...
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Analysis of random mutations in Salmonella Gallinarum dihydropteroate synthase conferring sulfonamide resistance
In bacteria and primitive eukaryotes, sulfonamide antibiotics block the folate pathway by inhibiting dihydropteroate synthase (FolP) that combines...
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Quantitative systems-based prediction of antimicrobial resistance evolution
Predicting evolution is a fundamental problem in biology with practical implications for treating antimicrobial resistance, which is a complex...
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Modeling Water Erosion
Modeling soil erosion is important for understanding the processes governing soil erosion, predicting runoff and soil erosion rates, and identifying...
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Rethinking connectivity modeling for high-mobility ungulates: insights from a globally endangered equid
ContextMaintaining connectivity is crucial for wildlife conservation in human-occupied landscapes. Structural connectivity modeling (SCM) attempts to...
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Tracking Antibiotic Resistance from the Environment to Human Health
Antimicrobial resistance (AMR) is one of the threats to our world according to the World Health Organization (WHO). Resistance is an evolutionary...
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Modeling stress-induced responses: plasticity in continuous state space and gradual clonal evolution
Mathematical models of cancer and bacterial evolution have generally stemmed from a gene-centric framework, assuming clonal evolution via acquisition...
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A high-throughput phenoty** method for sugarcane rind penetrometer resistance and breaking force characterization by near-infrared spectroscopy
BackgroundSugarcane ( Saccharum spp. ) is the core crop for sugar and bioethanol production over the world. A major problem in sugarcane production is...
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Blood–Brain Barrier Transwell Modeling
AbstractIn vitro blood–brain barrier (BBB) modeling with the use of the brain endothelial cells grown on a transwell membrane is widely used to...
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Identification of novel single nucleotide variants in the drug resistance mechanism of Mycobacterium tuberculosis isolates by whole-genome analysis
BackgroundTuberculosis (TB) represents a major global health challenge. Drug resistance in Mycobacterium tuberculosis (MTB) poses a substantial...
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Model-informed experimental design recommendations for distinguishing intrinsic and acquired targeted therapeutic resistance in head and neck cancer
The promise of precision medicine has been limited by the pervasive resistance to many targeted therapies for cancer. Inferring the timing (i.e.,...
