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Genome Editing-Based Strategies Used to Enhance Crop Resistance to Parasitic Weeds
In contrast to most autotrophic plants, which produce carbohydrates from carbon dioxide using photosynthesis, parasitic weed plants rely on host... -
Role of Induced Resistance in Insect-Pest Management
Induced resistance is a process by which plants increase their resistance against pathogens and herbivores through the activation of their own... -
In vivo photocontrol of orexin receptors with a nanomolar light-regulated analogue of orexin-B
Orexinergic neurons are critically involved in regulating arousal, wakefulness, and appetite. Their dysfunction has been associated with slee**...
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Oral glucagon-like peptide 1 analogue ameliorates glucose intolerance in db/db mice
ObjectivesWe constructed a recombinant oral GLP-1 analogue in Lactococcus lactis ( L. lactis ) and evaluated its physiological functions.
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Recent Strategies to Combat Multidrug Resistance
Multidrug resistance (MDR) has emerged as one of the most important global health issues of the twenty-first century, posing serious threats to... -
KIT mutations and expression: current knowledge and new insights for overcoming IM resistance in GIST
Gastrointestinal stromal tumor (GIST) is the most common sarcoma located in gastrointestinal tract and derived from the interstitial cell of Cajal...
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Perspectives for plant biology in space and analogue environments
Advancements in plant space biology are required for the realization of human space exploration missions, where the re-supply of resources from Earth...
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Mechanisms of Mycobacterium tuberculosis Drug Resistance
AbstractThe review presents the results of investigations of the mechanisms of action of long-used and new antituberculosis drugs, and information...
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Molecular mechanisms governing antifungal drug resistance
Fungal pathogens are a severe public health problem. The leading causative agents of systemic fungal infections include species from the Candida , Cryptococcus...
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Strigolactone signaling gene from soybean GmMAX2a enhances the drought and salt-alkaline resistance in Arabidopsis via regulating transcriptional profiles of stress-related genes
Strigolactone (SL) is a new plant hormone, which not only plays an important role in stimulating seed germination, plant branching, and regulating...
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Expression profiling and characterization of key RGA involved in lentil Fusarium wilt Race 5 resistance
Fusarium wilt is a major threat to lentil production in India and worldwide. The presence of evolving virulent races has imposed the necessity of...
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Breeding for Resistance to Biotic and Abiotic Stresses and Quality Traits in Chilli
The Capsicum genus originated in Central America and includes approximately 35 species, which includes five domesticated species (C. annuum, C.... -
Inhibiting fatty acid synthesis overcomes colistin resistance
Treating multidrug-resistant infections has increasingly relied on last-resort antibiotics, including polymyxins, for example colistin. As polymyxins...
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USP24-i-101 targeting of USP24 activates autophagy to inhibit drug resistance acquired during cancer therapy
Drug resistance in cancer therapy is the major reason for poor prognosis. Addressing this clinically unmet issue is important and urgent. In this...
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Venetoclax therapy and emerging resistance mechanisms in acute myeloid leukaemia
Acute myeloid leukaemia (AML) is a highly aggressive and devastating malignancy of the bone marrow and blood. For decades, intensive chemotherapy has...
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Overexpression of an apple broad range agglutinating lectin does not promote in planta resistance to fire blight and bacterial wilt
Lectins, a large group of proteins present in all kingdoms of life can bind reversibly to glycans. The roles of plant lectins are diverse and include...
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Callose deposition regulates differences in cotton aphid resistance among six watermelon varieties
Cotton aphids ( Aphis gossypii Glover) are important pests of cucurbit crops. Plant defenses at different cell layers, including the leaf surface,...
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Disruption of the Novel Small Protein RBR7 Leads to Enhanced Plant Resistance to Blast Disease
Plant disease is a threat to global food security. Breeding crops carrying broad-spectrum resistance loci is an effective way to control infectious...
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Wheat Rusts: Current Status, Prospects of Genetic Control and Integrated Approaches to Enhance Resistance Durability
The three rusts are the most damaging diseases of wheat worldwide and continue to pose a threat to global food security. In the recent decades, stem... -
The acetylation of pknH is linked to the ethambutol resistance of Mycobacterium tuberculosis
EmbR, a substrate of pknH in Mycobacterium tuberculosis (Mtb), is related to the ethambutol (EMB) resistance. This study aimed to investigate the...