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A Hands-On Guide to Generate Spatial Gene Expression Profiles by Integrating scRNA-seq and 3D-Reconstructed Microscope-Based Plant Structures
Transcriptome profiles of individual cells in the plant are strongly dependent on their relative position. Cell differentiation is associated with...
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A time-resolved meta-analysis of consensus gene expression profiles during human T-cell activation
BackgroundThe coordinated transcriptional regulation of activated T-cells is based on a complex dynamic behavior of signaling networks. Given an...
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Expression profiles and bioinformatic analysis of microRNAs in myocardium of diabetic cardiomyopathy mice
BackgroundMicroRNAs (miRNAs) can regulate expression of target genes at post transcriptional level, and mediate the pathophysiological process of...
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Dataset including whole blood gene expression profiles and matched leukocyte counts with utility for benchmarking cellular deconvolution pipelines
ObjectivesCellular deconvolution is a valuable computational process that can infer the cellular composition of heterogeneous tissue samples from...
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Relationships between the expression of adipose genes and profiles of hospitalized dogs
Obesity is one of the risk factors for the onset of various metabolic diseases in dogs. Energy expenditure in brown/beige adipocytes, which is...
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Disruption of Long-Distance Transport Leads to Changes in Gene Expression Profiles of Sugar Transporters in Silver Birch
AbstractKarelian birch is a form of silver birch that is characterized by a violation of the ratio and spatial orientation of the structural elements...
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Identification of lncRNA, miRNA and mRNA expression profiles and ceRNA Networks in small cell lung cancer
BackgroundSmall cell lung cancer (SCLC) is a highly lethal malignant tumor. It accounts for approximately 15% of newly diagnosed lung cancers. Long...
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Niche–dependent sponge hologenome expression profiles and the host-microbes interplay: a case of the hawaiian demosponge Mycale Grandis
BackgroundMost researches on sponge holobionts focus primarily on symbiotic microbes, yet data at the level of the sponge hologenome are still...
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TIP aquaporins in Cyperus esculentus: genome-wide identification, expression profiles, subcellular localizations, and interaction patterns
BackgroundTonoplast intrinsic proteins (TIPs), which typically mediate water transport across vacuolar membranes, play an essential role in plant...
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Identification of drug responsive enhancers by predicting chromatin accessibility change from perturbed gene expression profiles
Individual may response to drug treatment differently due to their genetic variants located in enhancers. These variants can alter transcription...
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High-dimensional gene expression and morphology profiles of cells across 28,000 genetic and chemical perturbations
Cells can be perturbed by various chemical and genetic treatments and the impact on gene expression and morphology can be measured via transcriptomic...
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Expression profiles of genes involved in sugar metabolism during fruit development and ripening of paprika (Capsicum annuum L.)
Paprika ( Capsicum annuum L.) is a mild pepper with larger fruit and thicker fruit skin than common chilli and bell peppers. The process of fruit...
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Expression Profiles of Protease in Onychomycosis-Related Pathogenic Trichophyton rubrum and Tinea Capitis-Related Pathogenic Trichophyton violaceum
The two fungal species Trichophyton rubrum and Trichophyton violaceum are common pathogens on human, infecting keratinized tissue of the outer body...
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Characterization of gene expression profiles in the mouse brain after 35 days of spaceflight mission
It has been proposed that neuroinflammatory response plays an important role in the neurovascular remodeling in the brain after stress. The goal of...
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Comparative Transcriptomics Reveals Novel Spatial Gene Expression Profiles in Cotton (Gossypium hirsutum L.) Under Herbivory and Drought Stress
Cotton is the major natural fiber-producing crop, contributing significantly to the global textile economy. However, the cotton crop encounters...
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Rapid adjustment of cone opsin expression profiles may help Western mosquitofish (Gambusia affinis) maintain foraging efficiency in distinct light environments
Vertebrates rely on two special groups of photoreceptor cells (rods and cones) in the retina to receive visual information. Five opsin families in...
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Multiple sclerosis patient-derived spontaneous B cells have distinct EBV and host gene expression profiles in active disease
Epstein–Barr virus (EBV) is an aetiologic risk factor for the development of multiple sclerosis (MS). However, the role of EBV-infected B cells in...
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The m6A methylation and expression profiles of mouse neural stem cells after hypoxia/reoxygenation
BackgroundIschemia–reperfusion injury to the central nervous system often causes severe complications. The activation of endogenous neural stem cells...
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A multi-tissue de novo transcriptome assembly and relative gene expression of the vulnerable freshwater salmonid Thymallus ligericus
Freshwater ecosystems are among the most endangered ecosystems worldwide. While numerous taxa are on the verge of extinction as a result of global...
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Expression profiles of the autism-related SHANK proteins in the human brain
BackgroundSHANKs are major scaffolding proteins at postsynaptic densities (PSDs) in the central nervous system. Mutations in all three family members...
