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Biotransformation of benzaldehyde into l-phenylacetylcarbinol using magnetic nanoparticles-coated yeast cells
ObjectivesThe yeast cells were coated with Fe 3 O 4 magnetic nanoparticles and employed as biocatalyst for the microbial biotransformation of...
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Process optimization for biosynthesis of pyruvate decarboxylase (PDC) and Neuberg’s ketol (PAC) from a novel Pichia cecembensis through response surface methodology
PurposePhenylacetylcarbinol (PAC) is an intermediate for the synthesis of several active pharmaceutical ingredients (ephedrine, pseudoephedrine,...
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Enzymes in the Chemical and Pharmaceutical Industry
Enzymes are used today in the chemical and pharmaceutical industry to produce a wide range of products. In this chapter, you will be introduced to...
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Biotransformation using halotolerant yeast in seawater: a sustainable strategy to produce R-(−)-phenylacetylcarbinol
Acyloin condensation between benzaldehyde and decarboxylated pyruvate results in the production of R -(−)-phenylacetylcarbinol, a chiral precursor of...
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Microbial Production of Natural Flavors and Fragrances
Due to global warming, with climate changes and significantly decreasing petrochemical resources, an urgent need has arisen to produce bio-based...
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Recent developments in the biology and biotechnological applications of halotolerant yeasts
AbstractNatural hypersaline environments are inhabited by an abundance of prokaryotic and eukaryotic microorganisms capable of thriving under extreme...
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Polymerized Ionic Liquids as Antimicrobial Materials
Ionic liquids (ILs) are salts composed of a large organic or inorganic cation in which an alkyl chain is replaced or inorganic or organic anions....
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L-phenylacetylcarbinol production by yeast petite mutants
The yeast Saccharomyces cerevisiae is able to biotransform benzaldehyde into L-phenylacetylcarbinol (L-PAC), a key intermediate in the production of...
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Enzyme in der chemischen und pharmazeutischen Industrie
In diesem Kapitel wird die Verwendung von Enzymen zur Herstellung von Produkten in der chemischen und pharmazeutischen Industrie vorgestellt....
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Characterization of aromatic aminotransferases from Ephedra sinica Stapf
Ephedra sinica Stapf (Ephedraceae) is a broom-like shrub cultivated in arid regions of China, Korea and Japan. This plant accumulates large amounts...
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Potential of some yeast strains in the stereoselective synthesis of (R)-(−)-phenylacetylcarbinol and (S)-(+)-phenylacetylcarbinol and their reduced 1,2-dialcohol derivatives
Whole cells of different yeast species have been widely used for a number of asymmetric transformations. In the present study, the screening of...
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Candida utilis and Cyberlindnera (Pichia) jadinii: yeast relatives with expanding applications
The yeast Candida utilis is used as a food additive and as a host for heterologous gene expression to produce various metabolites and proteins....
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Enzymes useful for chiral compound synthesis: structural biology, directed evolution, and protein engineering for industrial use
Biocatalysts (enzymes) have many advantages as catalysts for the production of useful compounds as compared to chemical catalysts. The...
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Acetohydroxyacid synthases: evolution, structure, and function
Acetohydroxyacid synthase, a thiamine diphosphate-dependent enzyme, can condense either two pyruvate molecules to form acetolactate for synthesizing...
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Non-terpenoid biotransformations by Mucor species
Biotransformation is an important tool for the structural modification of organic compounds, especially natural products with complex structures,...
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Farming Amphetamines: Khat (Catha edulis Forsk.) a Traditional Plant with Mild Stimulating Psychoactive and Medicinal Properties
Khat (Catha edulis Forsk., Celastraceae) is a flowering perennial shrub with a long history of use and cultivation in East Africa and the Arabian...
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Enzymatic synthesis of l-norephedrine by coupling recombinant pyruvate decarboxylase and ω-transaminase
l -Norephedrine, a natural plant alkaloid, possesses similar activity as ephedrine and can be used as a vicinal amino alcohol for the asymmetric...
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In situ product removal in fermentation systems: improved process performance and rational extractant selection
The separation of inhibitory compounds as they are produced in biotransformation and fermentation systems is termed in situ product removal (ISPR)....
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Effects of encapsulation of microorganisms on product formation during microbial fermentations
This paper reviews the latest developments in microbial products by encapsulated microorganisms in a liquid core surrounded by natural or synthetic...
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The effects of polymer phase ratio and feeding strategy on solid–liquid TPPBs for the production of l-phenylacetylcarbinol from benzaldehyde using Candida utilis
Purpose of WorkTo increase the bioproduction of l -phenylacetylcarbinol (PAC), a precursor molecule in the synthesis of the decongestants ephedrine...
