Enzymes in the Chemical and Pharmaceutical Industry

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Introduction to Enzyme Technology

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Abstract

Enzymes are used today in the chemical and pharmaceutical industry to produce a wide range of products. In this chapter, you will be introduced to product categories like bulk chemicals, fine chemicals, or active pharmaceutical ingredients (APIs) and some areas in which enzymes can offer benefits over existing production processes, like reduction of waste or higher product purity. In addition to these production processes, in which the enzyme acts as a catalyst for a particular reaction, you will learn that in the pharmaceutical industry enzymes are studied as well for their biological functions. These functions may range from being a target of a drug, i.e., an enzyme that should be inhibited, to being involved in the metabolism of a drug to being a drug itself. Overall, you will get to know the historical and present-day applications of enzymes in these two industries, as well as some recent developments like synthetic biology.

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References

  • Ashina Y, Suto M, Endo T. Nitrile hydratase. Encyclopedia of industrial biotechnology. Hoboken: Wiley; 2010.

    Google Scholar 

  • Bommarius AS, Riebel B. Biocatalysis. Weinheim: Wiley-VCH Verlag GmbH; 2004.

    Book  Google Scholar 

  • Boniello C, Mayr T, Klimant I, Koenig B, Riethorst W, Nidetzky B. Biotechnol Bioeng. 2010;106(4):528–40.

    Article  CAS  PubMed  Google Scholar 

  • Breinbauer R, Vetter IR, Waldmann H. Angew Chem Int Ed. 2002;41(16):2878.

    Article  CAS  Google Scholar 

  • Buchholz K, Kasche V, Bornscheuer UT. Biocatalysts and enzyme technology. 2nd ed. Weinheim: Wiley-VCH Verlag GmbH; 2012.

    Google Scholar 

  • Buchner E. Ber Dtsch Chem Ges. 1897;30:117–24.

    Article  CAS  Google Scholar 

  • Grunwald P, editor. Industrial biocatalysis. Singapore: Pan Stanford Publishing Pte. Ltd.; 2015.

    Google Scholar 

  • Ladkau N, Assmann M, Schrewe M, Julsing MK, Schmid A, Bühler B. Metab Eng. 2016;36:1–9.

    Article  CAS  PubMed  Google Scholar 

  • Liese A, Seelbach K, Wandrey C, editors. Industrial biotransformations. 2nd ed. Weinheim: Wiley-VCH Verlag GmbH; 2006.

    Google Scholar 

  • Marschall L. Im Schatten der chemischen Synthese. Industrial biotechnology in Germany (1900–1907). Frankfurt a. M: Campus Verlag; 2000.

    Google Scholar 

  • Neuberg C, Hirsch J. Biochem Z. 1921;115:282–310.

    CAS  Google Scholar 

  • Peterson DH, Murray HC, Eppstein SH, Reineke LM, Weintraub A, Meister PD, Leigh HM. J Am Chem Soc. 1952;74:5933–396.

    Article  CAS  Google Scholar 

  • Reichstein T, Grüssner A. Helv Chem Acta. 1934;17:311–28.

    Article  CAS  Google Scholar 

  • Savile CK, Janey JM, Mundorff EC, Moore JC, Tam S, Jarvis WR, Colbeck JC, Krebber A, Fleitz FJ, Brands J, Devine PN, Huisman GW, Hughes GJ. Science. 2010;329(5989):305–9.

    Article  CAS  PubMed  Google Scholar 

  • Schmid RD, Urlacher VB. Modern biooxidation: enzymes, reactions and applications. Weinheim: Wiley-VCH; 2007.

    Book  Google Scholar 

  • Schroer K, Kittelmann M, Lütz S. Biotechnol Bioeng. 2010;106(5):699.

    Article  CAS  PubMed  Google Scholar 

  • Sheldon RA. Chem Commun. 2008:3352–65.

    Google Scholar 

  • Syldatk C, Hauer B, May O. BIOspektrum. 2001;2(01):145–7.

    Google Scholar 

  • Weizmann C. 1919; US Patent 1,315,585.

    Google Scholar 

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Correspondence to Stephan Lütz .

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Schwarz, J., Volmer, J., Lütz, S. (2024). Enzymes in the Chemical and Pharmaceutical Industry. In: Jaeger, KE., Liese, A., Syldatk, C. (eds) Introduction to Enzyme Technology. Learning Materials in Biosciences. Springer, Cham. https://doi.org/10.1007/978-3-031-42999-6_14

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