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Palmitic acid induces lipid droplet accumulation and senescence in nucleus pulposus cells via ER-stress pathway
Intervertebral disc degeneration (IDD) is a highly prevalent musculoskeletal disorder affecting millions of adults worldwide, but a poor...
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Inhibition of palmitic acid induced adipogenesis by natural polyphenols in 3T3-L1 adipocytes
AbstractDietary free fatty acids induce preadipocyte differentiation in the presence of a hormonal cocktail in 3T3-L1 adipocytes. Plant polyphenols...
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Dysregulated palmitic acid metabolism promotes the formation of renal calcium-oxalate stones through ferroptosis induced by polyunsaturated fatty acids/phosphatidic acid
The pathogenesis of renal calcium-oxalate (CaOx) stones is complex and influenced by various metabolic factors. In parallel, palmitic acid (PA) has...
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Proteomic analysis reveals USP7 as a novel regulator of palmitic acid-induced hepatocellular carcinoma cell death
Nutrient surplus and consequent free fatty acid accumulation in the liver cause hepatosteatosis. The exposure of free fatty acids to cultured...
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Nutrient intake, digestibility, and serum metabolites in dairy cows fed diets differing in starch concentration with palmitic acid or stearic acid supplementation postpartum
The present study determined the effect of supplementing palmitic acid (PA) and stearic acid (SA) on the nutrient intake, digestibility, and serum...
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Palmitic acid control of ciliogenesis modulates insulin signaling in hypothalamic neurons through an autophagy-dependent mechanism
Palmitic acid (PA) is significantly increased in the hypothalamus of mice, when fed chronically with a high-fat diet (HFD). PA impairs insulin...
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Reprogramming of palmitic acid induced by dephosphorylation of ACOX1 promotes β-catenin palmitoylation to drive colorectal cancer progression
Metabolic reprogramming is a hallmark of cancer. However, it is not well known how metabolism affects cancer progression. We identified that...
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The oleic/palmitic acid imbalance in exosomes isolated from NAFLD patients induces necroptosis of liver cells via the elongase-6/RIP-1 pathway
Excessive toxic lipid accumulation in hepatocytes underlies the development of non-alcoholic fatty liver disease (NAFLD), phenotypically...
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Palmitic acid causes increased dihydroceramide levels when desaturase expression is directly silenced or indirectly lowered by silencing AdipoR2
BackgroundAdipoR1 and AdipoR2 (AdipoRs) are plasma membrane proteins often considered to act as adiponectin receptors with a ceramidase activity....
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Molecular and functional characterization of the retinol-binding protein 4 (RBP4) in hepatocytes of Schizothorax prenanti in response to palmitic acid
Retinol-binding protein 4 (RBP4) protein is a kind of adipokines synthesized and secreted by the liver, which has been verified to play important...
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Exosomes secreted by palmitic acid-treated hepatocytes promote LX-2 cell activation by transferring miRNA-107
Activation of hepatic stellate cells (HSCs) is a key inducer of liver fibrogenesis in nonalcoholic fatty liver disease (NAFLD). Exosomes play an...
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Palmitic- and Stearic Acid-based Dry Vegetable Fat Prills Augment Milk Performance of Crossbred Dairy Cows
This study examined the impact of supplementing rumen-inert dry saturated free fatty acid prills (SFAP) using seven crossbred dairy cows in...
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Fatty Acid Characterization of “Gulcan 2 × Lauranne” and “Guara × Nurlu” F1 Hybrid Almond Population
Almond ( Amygdalus communis L.) is a type of hard-shell fruit species that is very important for human health due to its nutritional content. This...
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Astragaloside IV inhibits palmitic acid-induced apoptosis through regulation of calcium homeostasis in mice podocytes
Loss of podocytes is a hallmark of diabetic nephropathy, and a growing body of evidence indicates that podocytes are susceptible to palmitic acid...
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Fatty acid metabolism changes in association with neurobehavioral deficits in animal models of fetal alcohol spectrum disorders
Fetal alcohol spectrum disorders (FASD) show behavioral problems due to prenatal alcohol exposure (PAE). A previous study reports changes in gene...
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Phytohormonal impacts on fatty acid profiles in Chlorella vulgaris Beijerinck: endogenous identification and exogenous application of cytokinins and abscisic acid
Chlorella vulgaris has a high lipid content with potential for biofuel application. With a rapid growth cycle and ease of culture, it is well suited...
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Integrated Effects of Nitrogen Fertilizer, Biochar, and Salicylic Acid on Yield and Fatty Acid Profile of Six Rapeseed Cultivars
This study was conducted to evaluate the effect of nitrogen fertilizer with biochar and foliar application of salicylic acid on physiological traits,...
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Molecular characterization and functional analysis of apoptosis-inducing factor (AIF) in palmitic acid-induced apoptosis in Ctenopharyngodon idellus kidney (CIK) cells
Palmitic acid (PA), the most common saturated free fatty acid, may cause apoptosis when overloaded in non-fat cells. Apoptosis-inducing factor (AIF)...
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Effects of adding rumen-protected palm oil in diet on milk fatty acid profile and lipid health indices in Kivircik ewes
This study aimed to determine the effect of the addition of rumen-protected palm oil making up 3% of the ration on lipid health indices and milk...
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Variation in the fatty acid composition of microalgal lipids due to the effect of the extraction method
Lipid extraction from microalgae was studied more specifically considering the effects of the extraction method and solvent mixture on cell walls. Chlo...
