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Role of albumin in the metabolism and excretion of ochratoxin A
Ochratoxin A (OTA) is known to be strongly bound to serum albumin, but it remains unknown how albumin affects its metabolism and kinetics. To close...
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Biodegradation of ochratoxin A by endophytic Trichoderma koningii strains
Ochratoxin A (OTA) is a mycotoxin produced by Aspergillus spp. and Penicillium spp . that causes a threat to food safety and human health. Fungal...
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Protective Effect of Boric Acid Against Ochratoxin A-Induced Toxic Effects in Human Embryonal Kidney Cells (HEK293): A Study on Cytotoxic, Genotoxic, Oxidative, and Apoptotic Effects
The present study evaluates the protective properties of boric acid (BA) against the toxic effects induced by ochratoxin A (OTA) in human embryonic...
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A new and promiscuous α/β hydrolase from Acinetobacter tandoii DSM 14970 T inactivates the mycotoxin ochratoxin A
AbstractThe presence of ochratoxin A (OTA) in food and feed represents a serious concern since it raises severe health implications. Bacterial...
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The nephrotoxin ochratoxin a impairs resilience of energy homeostasis of human proximal tubule cells
Despite a long history of research, the mode of action of the mycotoxin ochratoxin A (OTA) is still not clear. Based on our observation that...
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Bacillus licheniformis M2-7 Decreases Ochratoxin A Concentrations in Coffee Beans During Storage
Microbial contamination of coffee beans arises from various factors such as harvesting, handling, and storage practices, during which ochratoxin A...
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Occurrence of ochratoxin A in breast milk and urine samples of nursing mothers in Bangladesh
The mycotoxin ochratoxin A (OTA) is a potent nephrotoxin with carcinogenic properties and, thus, of concern as a food contaminant. Since food...
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Ochratoxin A induces abnormal tryptophan metabolism in the intestine and liver to activate AMPK signaling pathway
BackgroundOchratoxin A (OTA) is a mycotoxin widely present in raw food and feed materials and is mainly produced by Aspergillus ochraceus and Penicill...
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Biomonitoring of ochratoxin A, 2′R-ochratoxin A and citrinin in human blood serum from Switzerland
Biomonitoring of mycotoxins and their metabolites in biological fluids is increasingly used to assess human exposure. In this study, biomarkers of...
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AnAzf1 acts as a positive regulator of ochratoxin A biosynthesis in Aspergillus niger
AbstractAspergillus niger produces genotoxic and carcinogenic ochratoxin A (OTA) that severely threatens human and animal health. Transcription...
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Genome-Based Analysis of Aspergillus niger Aggregate Species from China and Their Potential for Fumonisin B2 and Ochratoxin A Production
Based on entire genome sequencing, this study focused on the classification of Aspergillus niger aggregation species and investigated their potential...
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Investigation of aflatoxin and ochratoxin A contamination of seized cannabis and cannabis resin samples
Recreational cannabis is being legalized in more and more countries, and methods for the determination of contaminants, thereunder mycotoxins, start...
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Biosynthesis of gold nanoparticles by Penicillium rubens and catalytic detoxification of ochratoxin A and organic dye pollutants
The environmental pollution caused by chemical dyes is a growing concern nowadays. Limitations of traditional methods opened the route for...
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LaeA regulates morphological development and ochratoxin A biosynthesis in Aspergillus niger
The global regulator LaeA and its orthologs govern the morphogenetic development and secondary metabolism of several filamentous ascomycetes. In Asperg...
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Unveiling the emerging role of curcumin to alleviate ochratoxin A-induced muscle toxicity in grass carp (Ctenopharyngodon idella): in vitro and in vivo studies
BackgroundOchratoxin A (OTA), a globally abundant and extremely hazardous pollutant, is a significant source of contamination in aquafeeds and is...
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Screening of Macrofungi Isolates for Aflatoxin B1 and Ochratoxin A Degradation
AbstractIn the present study, ninety-four macro fungi isolates were screened for aflatoxin B 1 and ochratoxin A degradation potential by their...
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Subchronic exposure of individual and combined ochratoxin A and citrinin selectively affects the expression of rat renal organic cation transporters
Ochratoxin A (OTA) and citrinin (CIT) are nephrotoxins found co-occurring in various human/animal food/feed and recognized as a health threat....
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Analysis of aflatoxins and ochratoxin a in chilli powder using ultrahigh performance liquid chromatography with fluorescence detection and tandem mass spectrometry
Chilli powder, a popular spice, is predominantly contaminated with aflatoxins (AFs) and ochratoxin A (OTA), posing a menace to public health. As no...
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Combined effects of cadmium and ochratoxin A on intestinal barrier dysfunction in human Caco-2 cells and pig small intestinal epithelial cells
Hazardous chemicals are commonly found in cereals and cereal-based products. However, most studies focus on the individual effects of these...
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Influence of processing steps on the fate of ochratoxin A, patulin, and alternariol during production of cloudy and clear apple juices
Mycotoxins are frequently found in fruits and fruit juices. However, data about occurrence and fate of mycotoxins along the fruit juice processing...
