Search
Search Results
-
Pros and cons for the evidence of adaptive non-shivering thermogenesis in marsupials
The thermogenic mechanisms supporting endothermy are still not fully understood in all major mammalian subgroups. In placental mammals, brown adipose...
-
A critical assessment of the role of creatine in brown adipose tissue thermogenesis
Brown adipose tissue is specialized for non-shivering thermogenesis, combining lipolysis with an extremely active mitochondrial electron transport...
-
PITPNC1 promotes the thermogenesis of brown adipose tissue under acute cold exposure
Brown adipose tissue (BAT) plays an essential role in non-shivering thermogenesis. The phosphatidylinositol transfer protein, cytoplasmic 1 (PITPNC1)...
-
Quantitative analysis of metabolic fluxes in brown fat and skeletal muscle during thermogenesis
Adaptive thermogenesis by brown adipose tissue (BAT) dissipates calories as heat, making it an attractive anti-obesity target. Yet how BAT...
-
The serotonin transporter sustains human brown adipose tissue thermogenesis
Activation of brown adipose tissue (BAT) in humans is a strategy to treat obesity and metabolic disease. Here we show that the serotonin transporter...
-
Understanding the Roles of Selenium on Thyroid Hormone-Induced Thermogenesis in Adipose Tissue
Brown adipose tissue (BAT) and white adipose tissue (WAT) are known to regulate lipid metabolism. A lower amount of BAT compared to WAT, along with...
-
The multiple facets of mitochondrial regulations controlling cellular thermogenesis
Understanding temperature production and regulation in endotherm organisms becomes a crucial challenge facing the increased frequency and intensity...
-
Konjac glucomannan attenuate high-fat diet-fed obesity through enhancing β-adrenergic-mediated thermogenesis in inguinal white adipose tissue in mice
Konjac glucomannan (KGM) has been reported to prevent high-fat diet-induced obesity, and we study investigated whether dietary supplementation with...
-
Cold exposure induces lipid dynamics and thermogenesis in brown adipose tissue of goats
BackgroundAdaptive thermogenesis by brown adipose tissue (BAT) is important to the maintenance of temperature in newborn mammals. Cold exposure...
-
Evidence for increased thermogenesis in female C57BL/6J mice housed aboard the international space station
Sixteen-week-old female C57BL/6J mice were sacrificed aboard the International Space Station after 37 days of flight (RR-1 mission) and frozen...
-
The rs1421085 variant within FTO promotes brown fat thermogenesis
One lead genetic risk signal of obesity—the rs1421085 T>C variant within the FTO gene—is reported to be functional in vitro but lacks evidence at an...
-
ADRA1A–Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP
Noradrenaline (NA) regulates cold-stimulated adipocyte thermogenesis
1 . Aside from cAMP signalling downstream of β-adrenergic receptor activation, how...
-
Infrared Thermography Diagnostics of Subcutaneous Thermogenerators of Non-Shivering Thermogenesis
AbstractChanges in skin temperature induced by the factors causing the activation of non-shivering thermogenesis (NST) were quantitatively described,...
-
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1
The sympathetic nervous system–catecholamine–uncoupling protein 1 (UCP1) axis plays an essential role in non-shivering adaptive thermogenesis....
-
Slit3 secreted from M2-like macrophages increases sympathetic activity and thermogenesis in adipose tissue
Beiging of white adipose tissue (WAT) is associated with an increase of anti-inflammatory M2-like macrophages in WAT. However, mechanisms through...
-
Isothermal microcalorimetry measures UCP1-mediated thermogenesis in mature brite adipocytes
The activation of thermogenesis in adipose tissue has emerged as an important target for the development of novel anti-obesity therapies. Using...
-
Distinct and shared endothermic strategies in the heat producing tissues of tuna and other teleosts
Although most fishes are ectothermic, some, including tuna and billfish, achieve endothermy through specialized heat producing tissues that are...
-
Adipocyte IRE1α promotes PGC1α mRNA decay and restrains adaptive thermogenesis
Adipose tissue undergoes thermogenic remodeling in response to thermal stress and metabolic cues, playing a crucial role in regulating energy...
-
Transcriptomic profiles of muscular dystrophy with myositis (mdm) in extensor digitorum longus, psoas, and soleus muscles from mice
BackgroundTitinopathies are inherited muscular diseases triggered by genetic mutations in the titin gene. Muscular dystrophy with myositis ( mdm ) is...
