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Whole genome sequencing of Nontuberculous Mycobacterium (NTM) isolates from sputum specimens of co-habiting patients with NTM pulmonary disease and NTM isolates from their environment
BackgroundNontuberculous mycobacterium (NTM) species are ubiquitous microorganisms. NTM pulmonary disease (NTM-PD) is thought to be caused not by...
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Detection of clinically important non tuberculous mycobacteria (NTM) from pulmonary samples through one-step multiplex PCR assay
BackgroundThe burden of non-tuberculous mycobacterial (NTM) disease is increasing worldwide but still its diagnosis is delayed and it is mistaken as...
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Common Features of Environmental Mycobacterium chelonae from Colorado Using Partial and Whole Genomic Sequence Analyses
Nontuberculous mycobacteria (NTM) are environmentally acquired opportunistic pathogens that cause chronic lung disease in susceptible individuals....
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Profile of non-tuberculous mycobacteria amongst tuberculosis presumptive people in Cameroon
BackgroundCameroon is a tuberculosis (TB) burden country with a 12% positivity among TB presumptive cases. Of the presumptive cases with a negative...
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Nontuberculous Mycobacterium Infections in Lung Disease and Medical Interventions
Infection with nontuberculous mycobacteria (NTM) is on the rise all across the world. Lung disease due to NTM is more prevalent and frequent and is... -
Application of a new designed high resolution melting analysis for mycobacterial species identification
The Non-tuberculous mycobacterial (NTM) isolates should be distinguished from tuberculosis and identified at the species level for choosing an...
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River Sediments Downstream of Villages in a Karstic Watershed Exhibited Increased Numbers and Higher Diversity of Nontuberculous Mycobacteria
The impact of residential villages on the nontuberculous mycobacteria (NTM) in streams flowing through them has not been studied in detail. Water and...
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Intracellular iron accumulation facilitates mycobacterial infection in old mouse macrophages
Aging has a significant impact on the immune system, leading to a gradual decline in immune function and changes in the body’s ability to respond to...
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Recent Developments in the Diagnosis and Treatment of Non-Tuberculous Mycobacterial Infection
Non-tuberculous mycobacteria are known to have approximately 200 species that caused a wide array of infections and are present extensively in the... -
Molecular identification of non-tuberculous mycobacterial species isolated from extrapulmonary samples using real-time PCR and rpoB sequence analysis
Tuberculosis (TB) is one of the leading causes of mortality among infectious diseases and accounts for a serious health hazard wordwide. Apart from...
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Comparison of the sputum microbiome between patients with stable nontuberculous mycobacterial pulmonary disease and patients requiring treatment
BackgroundWe evaluated whether the sputum bacterial microbiome differs between nontuberculous mycobacteria pulmonary disease (NTM-PD) patients with...
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Molecular epidemiology of nontuberculous mycobacteria isolated from tuberculosis-suspected patients
It is a growing problem around the world to deal with nontuberculous mycobacteria infection (NTM), but its clinical significance is still largely...
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Molecular identification of multiple drug resistance (MDR) strain of Mycobacterium tuberculosis
Background and ObjectivesIsoniazid and rifampin are the first -line drugs against Mycobacterium tuberculosis . Resistance to these important drugs is...
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Molecular identification of nontuberculous mycobacteria using the rpoB, argH and cya genes analysis
Nontuberculous mycobacterial (NTM) infections are growing worldwide especially in immunocompromised individuals. Since treatment of NTM infections is...
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In vitro and ex vivo activity of the fluoroquinolone DC-159a against mycobacteria
Antimicrobial resistance is a global health problem. In 2021, it was estimated almost half a million of multidrug-resistant tuberculosis (MDR-TB)...
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Isolation of nontuberculous mycobacteria species from different water sources: a study of six hospitals in Tehran, Iran
PurposeNontuberculous mycobacteria (NTM) are ubiquitous bacteria that are naturally resistant to disinfectants and antibiotics and can colonize...
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Isolation and identification of nontuberculous mycobacteria from raw milk and traditional cheese based on the 16S rRNA and hsp65 genes, Tehran, Iran
As an important source of human food, milk can be a carrier of human pathogenic bacteria, including tuberculous and nontuberculous mycobacteria...
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A nontuberculous mycobacterium could solve the mystery of the lady from the Franciscan church in Basel, Switzerland
BackgroundIn 1975, the mummified body of a female has been found in the Franciscan church in Basel, Switzerland. Molecular and genealogic analyses...
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Self-recycling and partially conservative replication of mycobacterial methylmannose polysaccharides
The steep increase in nontuberculous mycobacteria (NTM) infections makes understanding their unique physiology an urgent health priority. NTM...
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New design of multilocus sequence analysis of rpoB, ssrA, tuf, atpE, ku, and dnaK for identification of Mycobacterium species
BackgroundDifferentiating Mycobacterium tuberculosis (MTB) from nontuberculous mycobacteria (NTM) is very important in the treatment process of...