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1. The Functions of N⁶-Methyladenosine in Nuclear RNAs

   Abstract

   N ⁶ -methyladenosine (m ⁶ A) is one of the most common modifications in both eukaryotic and prokaryotic mRNAs. It has been experimentally...

   Nadezhda A. Zhigalova, Katerina Yu. Oleynikova, ... Alexander S. Ermakov in Biochemistry (Moscow)

   Article 01 January 2024
   

2. N⁶-methyladenosine modification—a key player in viral infection

   N ⁶ -methyladenosine (m ⁶ A) modification is a dynamic, reversible process and is the most prevalent internal modification of RNA. This modification is...

   **aoyue Zhang, Qiu Peng, Lujuan Wang in Cellular & Molecular Biology Letters

   Article Open access 12 October 2023
   

3. Ferroptosis: a critical mechanism of N⁶-methyladenosine modification involved in carcinogenesis and tumor progression

   Ferroptosis is an iron-dependent regulatory cell necrosis induced by iron overload and lipid peroxidation. It occurs when multiple redox-active...

   Qingqing Wei, Changning Xue, ... Ming Zhou in Science China Life Sciences

   Article 28 February 2024

4. Decoding epitranscriptomic regulation of viral infection: map** of RNA N⁶-methyladenosine by advanced sequencing technologies

   Elucidating the intricate interactions between viral pathogens and host cellular machinery during infection is paramount for understanding pathogenic...

   **angdong Fan, Yitong Zhang, ... Luoluo Wang in Cellular & Molecular Biology Letters

   Article Open access 27 March 2024
   

5. RBFOX2 recognizes N⁶-methyladenosine to suppress transcription and block myeloid leukaemia differentiation

   N ⁶ -methyladenosine (m ⁶ A) methylation can be deposited on chromatin-associated RNAs (caRNAs) by the RNA methyltransferase complex (MTC) to regulate...

   **aoyang Dou, Yu **ao, ... Chuan He in Nature Cell Biology

   Article Open access 28 August 2023
   

6. Transcriptome-wide N⁶-methyladenosine methylation profile of atherosclerosis in mice

   Background

   Atherosclerosis (AS) is a critical pathological event during the progression of cardiovascular diseases. It exhibits fibrofatty lesions on...

   **nbin Zheng, Bo Zhou, ... Minhua Gu in BMC Genomics

   Article Open access 14 December 2023
   

7. Construction of a risk model based on N⁶-methyladenosine-related lncRNAs for predicting the prognosis of breast cancer

   N ⁶ -methyladenosine modification and lncRNAs are closely related to the prognosis and immunotherapy response of breast cancer patients. LncRNAs...

   Wenxia Cui, Jiasheng Zhang, ... Youzhi Zhu in Journal of Biosciences

   Article 31 July 2023
   

8. N¹-Methyladenosine modification of mRNA regulates neuronal gene expression and oxygen glucose deprivation/reoxygenation induction

   N ¹ -Methyladenosine (m1A) is an abundant modification of transcripts, plays important roles in regulating mRNA structure and translation efficiency,...

   Zhangyang Qi, Chi Zhang, ... Hengxing Zhou in Cell Death Discovery

   Article Open access 12 May 2023
   

9. RNA N⁶-methyladenosine modification mediates downregulation of NR4A1 to facilitate malignancy of cervical cancer

   Background

   N ⁶ -methyladenosine is the most abundant eukaryotic mRNA modification and alters a wide range of cellular processes in cancer. Therefore,...

   Tao Yu, Fuxia Wu, ... Yankun Liu in Cell & Bioscience

   Article Open access 25 December 2022
   

10. Mass spectrometry-based proteomic landscape of rice reveals a post-transcriptional regulatory role of N⁶-methyladenosine

    Rice is one of the most important staple food and model species in plant biology, yet its quantitative proteomes are largely uncharacterized. Here we...

    Shang-Tong Li, Yunzhuo Ke, ... Zhe Liang in Nature Plants

    Article 12 July 2024
    

11. N⁶-methyladenosine-modified circ_104797 sustains cisplatin resistance in bladder cancer through acting as RNA sponges

    Background

    Bladder cancer (BCa) ranks among the predominant malignancies affecting the urinary system. Cisplatin (CDDP) remains a cornerstone...

    Congjie Xu, Jiaquan Zhou, ... Yang Wang in Cellular & Molecular Biology Letters

    Article Open access 23 February 2024
    

12. Transcriptome-wide profiling and quantification of N⁶-methyladenosine by enzyme-assisted adenosine deamination

    N ⁶ -methyladenosine (m ⁶ A), the most abundant internal messenger RNA modification in higher eukaryotes, serves myriad roles in regulating cellular...

    Yu-Lan **ao, Shun Liu, ... Weixin Tang in Nature Biotechnology

    Article 02 January 2023
    

13. N⁶-methyladenosine-mediated feedback regulation of abscisic acid perception via phase-separated ECT8 condensates in Arabidopsis

    N ⁶ -methyladenosine (m ⁶ A) is the most abundant internal modification in eukaryotic mRNAs, yet how plants recognize this chemical modification to...

    **aowei Wu, Tingting Su, ... Hao Yu in Nature Plants

    Article 06 March 2024
    

14. N⁶-Methyladenosine and physiological response divergence confer autotetraploid enhanced salt tolerance compared to its diploid Hordeum bulbosum

    Polyploid species have played an essential role in plant evolution, exemplified by adaptive advantages to abiotic stress. N ⁶ -Methyladenosine (m6A) is...

    Margaret Scarrow, Ning Chen, ... Genlou Sun in Physiology and Molecular Biology of Plants

    Article 10 December 2022
    

15. RNA N⁶-methyladenosine modification in female reproductive biology and pathophysiology

    Gene expression and posttranscriptional regulation can be strongly influenced by epigenetic modifications. N ⁶ -methyladenosine, the most extensive RNA...

    Erqing Huang, Lijuan Chen in Cell Communication and Signaling

    Article Open access 09 March 2023
    

16. Genome-wide identification of the N⁶-methyladenosine regulatory genes reveals NtFIP37B increases drought resistance of tobacco (Nicotiana tabacum L.)

    Background

    N ⁶ -methyladenosine (m ⁶ A) is one of the common internal RNA modifications found in eukaryotes. The m ⁶ A modification can regulate various...

    Huan Su, Lijun Meng, ... **g**g ** in BMC Plant Biology

    Article Open access 26 February 2024
    

17. N⁶-Methyladenosine-modified lncRNA LINREP promotes Glioblastoma progression by recruiting the PTBP1/HuR complex

    Glioblastoma multiforme (GBM) is acknowledged as the most aggressive primary brain tumor in adults. It is typically characterized by the high...

    **aoshuai Ji, Zihao Liu, ... Tao **n in Cell Death & Differentiation

    Article 23 July 2022
    

18. N⁶-methyladenosine (m⁶A) Writer WTAP Potentiates Hepatocellular Carcinoma Immune Evasion and Aerobic Glycolysis

    Hepatocellular carcinoma (HCC) is one of most prevalent malignant tumors with poor prognosis and a high mortality rate. Recent research indicates...

    Fatao Yu, Yuling Feng, ... Jian Sun in Cell Biochemistry and Biophysics

    Article 13 June 2024
    

19. ALKBH5-mediated N⁶-methyladenosine modification of TRERNA1 promotes DLBCL proliferation via p21 downregulation

    Long noncoding RNAs (lncRNAs) have crucial functions in the tumorigenesis and metastasis of cancers. N ⁶ -methyladenosine (m ⁶ A) modification of RNA is...

    Wei Song, Fei Fei, ... Juan Li in Cell Death Discovery

    Article Open access 14 January 2022
    

20. N⁶-methyladenosine modification of REG1α facilitates colorectal cancer progression via β-catenin/MYC/LDHA axis mediated glycolytic reprogramming

    Aerobic glycolysis has been considered as a hallmark of colorectal cancer (CRC). However, the potential functional regulators of glycolysis in CRC...

    Mingxia Zhou, **g He, ... Hongtao Wen in Cell Death & Disease

    Article Open access 25 August 2023