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Polypeptide-Based Multicomponent Materials: From Design to Applications
Polypeptides are of great interest to material scientists because of their functional versatility. The functionality of single-component polypeptide...
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First-row transition metal for isocyanide-involving multicomponent reactions (IMCR)
First-row transition metal catalyzed transformations that are able to construct complex molecules from simple, readily obtainable feedstocks have...
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Synthesis of Isonitrile Derivatives of Diglycerides and Carbohydrates as Intermediates for Multicomponent Ugi Reaction
AbstractRecently, there has been an increase in interest in multicomponent reactions, mainly due to the possibility of assembling of complex organic...
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Multicomponent DNAzyme Nanomachines: Structure, Applications, and Prospects
AbstractNucleic acids (NAs) are important components of living organisms responsible for the storage and transmission of hereditary information. They...
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Green preparation of new pyrimidine triazole derivatives via one-pot multicomponent reactions of guanidine
In this research the goal was to produce novel pyrimidine triazole compounds in high yields using triethylamin as an efficient catalyst. These new...
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Multicomponent reaction derived small di- and tri-carbohydrate-based glycomimetics as tools for probing lectin specificity
Lectins, carbohydrate-binding proteins, play important functions in all forms of life from bacteria and viruses to plants, animals, and humans,...
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Endothelial progenitor cell response to a multicomponent exercise training program in adults with cardiovascular risk factors
AimTo evaluate the effects of a multicomponent exercise program in the circulating levels of endothelial progenitor cells (EPCs) and endothelial...
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Precision in stereochemistry: the integral role of catalytic asymmetric Biginelli reaction in crafting enantiomerically pure dihydropyrimidinones
One well-known multicomponent reaction that is helpful in the synthesis of dihydropyrimidinones (DHPMs), important molecules in organic synthesis and...
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Enantiopure β-isocyano-boronic esters: synthesis and exploitation in isocyanide-based multicomponent reactions
Various boron-containing isocyanides have been efficiently synthesized from the corresponding enantiopure β-substituted β-amino boronic acid pinacol...
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Multicomponent synthesis of 3-(1H-indol-3-yl)-2-phenyl-1H-benzo[f]indole-4,9-dione derivatives
Herein, we report a one-pot greener methodology for the synthesis of 3-(1 H -indol-3-yl)-2-phenyl-1 H -benzo[ f ]indole-4,9-dione derivatives by the...
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Enzymatic Reactions in Unusual Reaction Media
The performance of enzymatic reactions in unusual reaction media offers a wide range of possibilities. Polar and nonpolar organic solvents,...
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Compositionality in Primate Gestural Communication and Multicomponent Signal Displays
Compositionality is the ability to combine meaningful elements into new combinations with novel meanings, and it has long been considered one of the...
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Application of phenacyl bromide analogs as a versatile organic intermediate for the synthesis of heterocyclic compounds via multicomponent reactions
Due to the increased interest in heterocyclic compounds over the past decade, many pharmaceutical and organic chemists have explored the synthesis of...
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Bacillus cereus extracellular vesicles act as shuttles for biologically active multicomponent enterotoxins
BackgroundExtracellular vesicles (EVs) from Gram-positive bacteria have gained considerable importance as a novel transport system of virulence...
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New oxacycles on the block: benzodioxepinones via a Passerini reaction
Oxacycles and benzoxepanes are privileged motifs present in a variety of natural products and functional molecules. However, their synthetic access...
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Catalytic resilience of multicomponent aromatic ring-hydroxylating dioxygenases in Pseudomonas for degradation of polycyclic aromatic hydrocarbons
Hydrophobic organic compounds, either natural or introduced through anthropogenic activities, pose a serious threat to all spheres of life, including...
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Ugi 5-center-4-component reaction of α-amino aldehydes and its application in synthesis of 2-oxopiperazines
A synthetic route leading to densely functionalized 2-oxopiperazines is presented. The strategy employs a 5-center-4-component variant of Ugi...
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Ultrasound-promoted convenient and ionic liquid [BMIM]BF4 assisted green synthesis of diversely functionalized pyrazolo quinoline core via one-pot multicomponent reaction, DFT study and pharmacological evaluation
An ultrasound-assisted green protocol for one-pot synthesis of a new series of pharmaceutically relevant pyrazolo quinoline derivatives ( 4a–t ) were...
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One-pot multicomponent synthesis of benzophenazine tethered tetrahydropyridopyrimidine derivatives
A simple, facile, and efficient green methodology has been developed for the synthesis of benzophenazine tethered tetrahydropyridopyrimidine...
