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An Optimized Cloud Computing Method for Extracting Molecular Descriptors
Extracting molecular descriptors from chemical compounds is an essential preprocessing phase for develo** accurate classification models....
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ISI Mitigation with Molecular Degradation in Molecular Communication
Inter-symbol interference (ISI) decreases the performance of diffusion based molecular communication (MC) significantly. Especially, considering the...
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A high quality, high molecular weight DNA extraction method for PacBio HiFi genome sequencing of recalcitrant plants
BackgroundPacBio HiFi sequencing provides highly accurate long-read sequencing datasets which are of great advantage for whole genome sequencing...
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Supported Molecular Matrix Electrophoresis
Distinct bands of mucins cannot be banded using a gel electrophoresis based on a molecular sieving effect due to their very large molecular weight...
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A new molecular method for fast differentiation of cockles Cerastoderma edule and Cerastoderma glaucum
Cerastoderma edule and C. glaucum are two species of cockles that co-exist in European waters. They are morphologically similar but exhibit...
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Prediction of the effects of small molecules on the gut microbiome using machine learning method integrating with optimal molecular features
BackgroundThe human gut microbiome (HGM), consisting of trillions of microorganisms, is crucial to human health. Adverse drug use is one of the most...
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Molecular Dynamics Simulations
Molecular simulations aim to supplement the design of new peptide molecules and the prediction of their conformational landscape. The response of...
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Molecular Docking
The rise in bioactive peptide discovery has driven the need to screen peptides in the early phases of drug discovery and development. Molecular...
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Using the Method of Molecular Modeling and Docking to Estimate the Potential Danger of Side Effects of Therapeutic Agents Used with Cardiac Amyloidosis
AbstractCardiac amyloidosis is a clinical pathology (usually of hereditary nature) initiated by the formation of amyloid fibrils, which has a high...
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Simple molecular based method for selected Oligochaeta (Annelida: Clitellata) genera identification
Aquatic Oligochaeta are one of most dominant taxa in freshwater sediments. Additionally, they have low dispersal capacity, and are highly sensitive...
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Enzymes in Molecular Biotechnology
Molecular biotechnology uses a wide variety of enzymes. These can be grouped either to their reaction mechanism (enzyme class) or to the intended use...
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LeMeDISCO is a computational method for large-scale prediction & molecular interpretation of disease comorbidity
To understand the origin of disease comorbidity and to identify the essential proteins and pathways underlying comorbid diseases, we developed LeMeDISCO...
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Discovery of novel Akt1 inhibitors by an ensemble-based virtual screening method, molecular dynamics simulation, and in vitro biological activity testing
Akt1, as an important member of the Akt family, plays a controlled role in cancer cell growth and survival. Inhibition of Akt1 activity can promote...
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Multiplex PCR-based molecular diagnostic method to detect cyantraniliprole-resistant I4790K mutation in the diamondback moth, Plutella xylostella (Lepidoptera: Plutellidae)
The diamondback moth Plutella xylostella (L.) (Lepidoptera: Plutellidae) is one of the most destructive insect pests worldwide which has developed...
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Molecular Structure of Starch
The physicochemical characteristics of starches from enormous sources show a very wide range, resulting in various functional properties, which are...
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Network pharmacology, molecular docking, and molecular dynamics simulation analysis reveal the molecular mechanism of halociline against gastric cancer
Halociline, a derivative of alkaloids, was isolated from the marine fungus Penicillium griseofulvum by our group. This remarkable compound exhibits...
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Identification of potential FAK inhibitors using mol2vec molecular descriptor-based QSAR, molecular docking, ADMET study, and molecular dynamics simulation
This study aims to identify potential focal adhesion kinase (FAK) inhibitors through an integrated computational approach, combining mol2vec...
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Molecular Markers for Harnessing Heterosis
The prominence of molecular markers has made substantial contributions to heterosis breeding. Efforts have been made for dissecting the molecular and...
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Molecular Mechanism of Yangshen Maidong Decoction in the Treatment of Chronic Heart Failure based on Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulations
Chronic heart failure (CHF) is a complex multifactorial clinical syndrome leading to abnormal cardiac structure and function. The severe form of this...
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Molecular Evolution in Australasian Marsupials
This chapter outlines the history of molecular evolutionary research in australidelphian marsupials, along with the genetic and genomic advances that...