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The performance of common SNP arrays in assigning African mitochondrial haplogroups
BackgroundMitochondrial haplogroup assignment is an important tool for forensics and evolutionary genetics. African populations are known to display...
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Morphotype is not linked to mitochondrial haplogroups of Caribbean acroporid hybrids
The Caribbean Acropora corals, A. palmata and A. cervicornis form a hybrid with two broad morphotypes, bushy and palmate. These morphotypes were...
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Maternal genetic diversity and phylogenetic analysis of Indian riverine and swamp buffaloes: insights from complete mitochondrial genomes
This study explored the genetic diversity and evolutionary history of riverine and swamp buffaloes in India, utilizing complete mitochondrial genome...
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Analysis of maternal genetic structure of mitochondrial DNA control region from Tai-Kadai-speaking Buyei population in southwestern China
BackgroundEven though the Buyei are a recognised ethnic group in southwestern China, there hasn’t been much work done on forensic population...
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Genetic variants affecting mitochondrial function provide further insights for kidney disease
BackgroundChronic kidney disease (CKD) is a complex disorder that has become a high prevalence global health problem, with diabetes being its...
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Association of mitochondrial DNA haplogroups J and K with low response in exercise training among Finnish military conscripts
BackgroundWe have previously suggested that some of the mutations defining mitochondrial DNA (mtDNA) haplogroups J and K produce an uncoupling effect...
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Association of mitochondrial DNA variation with high myopia in a Han Chinese population
High myopia (HM), which is characterized by oxidative stress, is one of the leading causes of visual impairment and blindness across the world....
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Mitochondrial Inheritance Following Nuclear Transfer: From Cloned Animals to Patients with Mitochondrial Disease
Mitochondria are indispensable power plants of eukaryotic cells that also act as a major biochemical hub. As such, mitochondrial dysfunction, which... -
Mitogenome sequences of domestic cats demonstrate lineage expansions and dynamic mutation processes in a mitochondrial minisatellite
BackgroundAs a population genetic tool, mitochondrial DNA is commonly divided into the ~ 1-kb control region (CR), in which single nucleotide variant...
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Between the lines: mitochondrial lineages in the heavily managed red deer population of Belarus
Here we report the first thorough genetic characterization of the long-understudied red deer population of Belarus in regards to its ancestry...
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Mitochondrial DNA Sequencing and Heteroplasmy Quantification by Next Generation Sequencing
Over the last 10 years, next generation sequencing (NGS) became the gold standard for both diagnosis and discovery of new disease genes responsible... -
Mitochondrial DNA and Alzheimer’s disease: a first case–control study of the Tunisian population
BackgroundAlzheimer’s disease (AD) is the most common neurodegenerative disorder in humans and presents a major health problem throughout the world....
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Whole mitochondrial genome sequencing provides new insights into the phylogeography of loggerhead turtles (Caretta caretta) in the Mediterranean Sea
Population structure and phylogeography of the loggerhead sea turtle ( Caretta caretta ) have so far been assessed mainly by mitochondrial DNA (mtDNA)...
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Secondary structure of the human mitochondrial genome affects formation of deletions
BackgroundAging in postmitotic tissues is associated with clonal expansion of somatic mitochondrial deletions, the origin of which is not well...
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Using Mitochondrial DNA in Human Identification
Mitochondrial DNA (mtDNA) has been employed for human identification in forensic caseworks since 1996. High copy number and uniparental inheritance... -
A Comparative Analysis of Mitochondrial Genome Mutation Spectra in Human Populations
Abstract —Nucleotide sequence variability of whole mitochondrial genomes (mtDNA) was analyzed and mutation spectra were reconstructed (by L-chain of...
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Isn’t It Time for Establishing Mitochondrial Nomenclature Breaking Mitochondrial Paradigm?
AbstractIn this work, we decided to initiate a discussion concerning heterogeneity of mitochondria, suggesting that it is time to build...
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Mitochondrial DNA diversity of the eastern black rhinoceros (Diceros bicornis michaeli) in Tanzania: implications for future conservation
There has been a drastic decline in the number of eastern black rhinoceros ( Diceros bicornis michaeli ) across Africa, leaving individuals restricted...
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Mitochondrial DNA
Mitochondria DNA (mtDNA) has distinct features from nuclear DNA. It has a circular DNA and coding its own genome. mtDNA consists of two regions,... -
Mitochondrial genetic diversity and haplotype distribution of golden jackal (Canis aureus, Linnaeus 1758) in Iran, a bridge from India to North Europe
Golden jackal ( Canis aureus ) is one of the most common canid in Iran and can be found in habitats from Southeast Asia to Europe. Its rapid range...