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SOX4 reversibly induces phenotypic changes by suppressing the epithelial marker genes in human keratinocytes
BackgroundSOX4 is a transcription factor belonging to the SOX (Sry-related High Mobility Group [HMG] box) family and plays a pivotal role in various...
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Pyramiding of blast and bacterial blight resistance genes in premium quality rice variety, BRRI dhan63 through marker-assisted breeding approach
Rice blast and bacterial blight diseases are the global threat for rice production. To develop blast and bacterial blight resistant lines, two blast...
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Introgression of blast and bacterial blight disease resistance genes in a rice genotype ADT43 through marker assisted back cross breeding
Bacterial Leaf Blight ( Xanthomonas oryzae pv. oryzae ) and blast ( Magnaporthe oryzae ) are the major biotic stresses around the rice-growing zones of...
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Analysis of the Ovarian Marker Genes Expression Revealed the Antagonistic Effects of Serotonin and Androstenedione on the Functional State of Mouse Granulosa Cells in Primary Culture
AbstractPrimary culture of granulosa cells is a prerequisite for a complete study of the normal functioning of the ovary and its pathologies. In this...
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Panton-Valentine Leukocidin (PVL) genes may not be a reliable marker for community-acquired MRSA in the Dakahlia Governorate, Egypt
BackgroundMethicillin-resistant Staphylococcus aureus is linked to both nosocomial and community infections. One of the key virulence factors of S....
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Cre-mediated autoexcision of selectable marker genes in soybean, cotton, canola and maize transgenic plants
Key messageEfficient selectable marker gene autoexcision in transgenic plants of soybean, cotton, canola, and maize is achieved by effective Cre...
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Marker-Assisted Simultaneous and Stepwise Pyramiding of Broad-Spectrum Bacterial Leaf Blight Resistance Genes, Xa33 and Xa38, into Salt-Tolerant Rice Variety “CO43”
Bacterial leaf blight (BLB) disease is one of the most important diseases of rice in India and worldwide. The management of this disease becomes...
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Marker-Assisted Selection in Wheat
Wheat is the world’s leading cereal grain crop, widely used due to its social and economic value. Wheat can grow in a wide range of climatic...
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Identification of novel marker-trait associations and candidate genes for combined low phosphorus and nitrogen-deficient conditions in rice at seedling stage
Rice responds to individual N and P deficiencies through root traits’ modifications and characteristic starvation responses. The genomic regions...
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Investigating Circadian Gating of Temperature Responsive Genes
Understanding gene expression dynamics in the context of the time of day and temperature response is an important part of understanding plant...
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Marker Assisted Recurrent Selection for Crop Improvement
Recurrent selection seeks to alter quantitatively transmitted traits in a specific way by gradually increasing the frequency of favourable alleles in...
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The landscape of PBMC methylome in canine mammary tumors reveals the epigenetic regulation of immune marker genes and its potential application in predicting tumor malignancy
BackgroundGenome-wide dysregulation of CpG methylation accompanies tumor progression and characteristic states of cancer cells, prompting a rationale...
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Specific Features of the Bank Vole Clethrionomys glareolus Marker Genes’ Expression Representing the Ecotoxicological Effects of a Dioxin-Contaminated Environment
AbstractIt is impossible to reliably evaluate the ecotoxicity of small subtoxic doses of dioxins without duly taking into account how the factors of...
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Marker-Assisted Breeding in Vegetable Crops
Molecular markers have great potential to improve the efficiency and precision of conventional plant breeding through marker-assisted selection...
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Trait Map**, Marker-Assisted Selection, and Introgression Breeding in Pearl Millet
Pearl millet (Pennisetum glaucum (l.) R. Br.) is a staple food crop in the arid and semi-arid tropics that is gaining importance as a...
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Development and validation a prognostic model based on natural killer T cells marker genes for predicting prognosis and characterizing immune status in glioblastoma through integrated analysis of single-cell and bulk RNA sequencing
BackgroundGlioblastoma (GBM) is an aggressive and unstoppable malignancy. Natural killer T (NKT) cells, characterized by specific markers, play...
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Integrated analysis of single-cell and bulk RNA sequencing identifies a signature based on macrophage marker genes involved in prostate cancer prognosis and treatment responsiveness
In the tumor microenvironment, tumor-associated macrophages (TAMs) interact with cancer cells and contribute to the progression of solid tumors....
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Genome-Informed Discovery of Genes and Framework of Functional Genes in Wheat
The complete reference genome of wheat was released in 2018 (IWGSC in Science 361:eaar7191, 2018), and since then many wheats genomic resources have...
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Enhancement of yield through marker-assisted pyramiding of yield contributing genes in rice (Oryza sativa L.) var. BPT5204
Enhancement of rice yield is a primary objective for the breeders to secure food supply to the ever-growing population. The present study aimed to...
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Molecular Marker: Genetic Improvement and Conservation of Industrial Crops
Molecular markers are of paramount importance in the field of crop enhancement as they facilitate the recognition and selection of favourable...