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S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) inhibits lung cancer tumorigenesis by regulating cell plasticity
BackgroundLung cancer is one of the most frequently diagnosed cancers characterized by high mortality, metastatic potential, and recurrence....
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Bcl-B: an “unknown” protein of the Bcl-2 family
Bcl-B is a poorly understood protein of the Bcl-2 family that is highly expressed in many healthy tissues and tumor types. Bcl-B is considered an...
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An update regarding the role of WNK kinases in cancer
Mammalian WNK kinases (WNKs) are serine/threonine kinases that contain four members, WNK1–4. They function to maintain ion homeostasis and regulate...
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Still no Rest for the Reductases: Ribonucleotide Reductase (RNR) Structure and Function: An Update
Herein we present a multidisciplinary discussion of ribonucleotide reductase (RNR), the essential enzyme uniquely responsible for conversion of...
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Pro-inflammatory cytokines stimulate CFTR-dependent anion secretion in pancreatic ductal epithelium
BackgroundLoss of CFTR-dependent anion and fluid secretion in the ducts of the exocrine pancreas is thought to contribute to the development of...
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Adenosylhomocysteinase like 1 interacts with nonstructural 5A and regulates hepatitis C virus propagation
Hepatitis C virus (HCV) life cycle is highly dependent on cellular proteins for viral propagation. In order to identify the cellular factors involved...
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Prey of Small Mammal-Eating Owls (Strix nebulosa, Bubo bubo) As a Source of Selective Accumulation of Palaeotheriological Material
AbstractThe accumulation of prey remains in the pellets of the great gray owl in the winter and nesting periods was studied over a number of years at...
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Influence of Chronic Man-made Pollution on Bromus inermis Genome Size
Abstract—Technogenic pollution can accelerate microevolutionary processes in natural populations. We estimated the nuclear DNA content of 10 Bromus...
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Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine
The relative contribution of intrinsic genetic factors and extrinsic environmental ones to cancer aetiology and natural history is a lengthy and...
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Communication between mitochondria and other organelles: a brand-new perspective on mitochondria in cancer
Mitochondria are energy factories of cells and are important pivots for intracellular interactions with other organelles. They interact with the...
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The Diet of the Great Gray Owl, Strix nebulosa, at Different Levels of Prey Abundance during the Nesting Season
Variation in the diet of the Great Gray Owl, a specialist predator, at different levels of prey abundance in different biotopes was studied in the...
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Intraspecific Differentiation of the Oriental Cuckoo (Cuculus optatus) within the Range: Relationship with the Abundance of Host Species
The distribution of C. optatus host-specific races within the breeding range has been analyzed. It has been found that these races are geographically...
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Exogenous and Endogenous Neuroactive Biogenic Amines: Studies with Lactococcus lactis subsp. lactis
AbstractThis work demonstrates that Lactococcus lactis subsp. lactis strains that display antimicrobial activity with respect to test cultures...
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New records of the heteroptera from the Middle Urals
71 heteropteran species belonging to 57 genera of 17 families are recorded for the first time for Sverdlovsk Province (the Middle Urals). Among them,...
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IP3 Receptor Properties and Function at Membrane Contact Sites
The inositol 1,4,5-trisphosphate (IP3) receptor (IP3R) is a ubiquitously expressed Ca2+-release channel localized in the endoplasmic reticulum (ER)....
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Role of hormones in regulating sodium transporters in the kidney: Modulation of phosphorylation, traffic, and expression
The review focuses on the key sodium transporters involved in maintaining water–salt balance in the kidney. The topography of sodium transporters is...
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Role of CFTR in epithelial physiology
Salt and fluid absorption and secretion are two processes that are fundamental to epithelial function and whole body fluid homeostasis, and as such...
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Helminth infestation of the moor frog (Rana arvalis Nilsson, 1842) and the Siberian tree frog (Rana amurensis Boulenger, 1886) in Western Siberia
The composition of helminths and infestation indices of two frog species of living in Western Siberia ( Rana arvalis ( n = 1082) and Rana amurensis ( n ...
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Structure of potential entomocomplex and its role in the feeding of bats in the plains of Middle Trans-Urals
The taxonomic and size structure of twilight and nocturnal insects inhabiting the plains of Middle Trans-Urals has been studied. The insect community...