Search
Search Results
-
The correlation between blood-lipid ratio in the first trimester and large-for-gestational-age infants
BackgroundTo investigate the correlation between maternal glucose and lipid metabolism indexes and blood-lipid ratio in the first trimester and...
-
A placenta-on-a-chip model to determine the regulation of FKBPL and galectin-3 in preeclampsia
Preeclampsia is a pregnancy-specific cardiovascular disorder, involving significant maternal endothelial dysfunction. Although inappropriate...
-
Prenatal vitamin intake in first month of pregnancy and DNA methylation in cord blood and placenta in two prospective cohorts
BackgroundPrenatal vitamin use is recommended before and during pregnancies for normal fetal development. Prenatal vitamins do not have a standard...
-
Sexually dimorphic methylation patterns characterize the placenta and blood from extremely preterm newborns
BackgroundHealth outcomes among children born prematurely are known to be sexually dimorphic, with male infants often more affected, yet the...
-
Imbalance of Angiogenic and Growth Factors in Placenta in Maternal Hyperhomocysteinemia
AbstractNumerous studies have shown that various adverse factors of different nature and action mechanisms have similar negative influence on...
-
Preeclampsia impedes foetal kidney development by delivering placenta-derived exosomes to glomerular endothelial cells
BackgroundFoetal renal dysplasia is still the main cause of adult renal disease. Placenta-derived exosomes are an important communication tool, and...
-
Proteome profiling of human placenta reveals developmental stage-dependent alterations in protein signature
IntroductionPlacenta is a complex organ that plays a significant role in the maintenance of pregnancy health. It is a dynamic organ that undergoes...
-
A proteomic profile of the healthy human placenta
BackgroundThe placenta remains one of the least studied organs within the human body. Yet, placental dysfunction has been associated with various...
-
Placenta-targeted Treatment Strategies for Preeclampsia and Fetal Growth Restriction: An Opportunity and Major Challenge
The placenta plays a crucial role in maintaining normal pregnancy. The failure of spiral artery remodeling (SAR) is a key factor leading to placental...
-
Morfofunctional and Molecular Changes in Placenta and Peripheral Blood in Preeclampsia and Gestational Diabetes Mellitus
AbstractGestational diabetes mellitus (GDM) and preeclampsia (PE) are common pregnancy complications with similar risk factors. Although GDM is...
-
Preparation of single-cell suspensions from the human placenta
Single-cell RNA-sequencing (scRNA-seq) allows the characterization of cellular composition and interactions in complex tissues. An essential...
-
Prenatal aripiprazole induces alterations of rat placenta: a histological, immunohistochemical and ultrastructural study
Antipsychotic drugs (APDs) are used to treat many psychiatric illnesses as schizophrenia. Typical antipsychotic drugs (TAPDs) are being used;...
-
Gene expression of iron transporters, markers of vascularization and structural integrity in placenta of mothers with and without anemia
ObjectiveTo compare the mRNA expression of placental iron transporters (TfR-1 and FPN), markers of placental vascularization (VEGF and sFLT1) and...
-
The important biological roles of Syncytin-1 of human endogenous retrovirus W (HERV-W) and Syncytin-2 of HERV-FRD in the human placenta development
Background: Human endogenous retroviruses (HERVs) entered the germ line by retroviral infection from a distant ancestor over 30 million years ago and...
-
The application of epiphenoty** approaches to DNA methylation array studies of the human placenta
BackgroundGenome-wide DNA methylation (DNAme) profiling of the placenta with Illumina Infinium Methylation bead arrays is often used to explore the...
-
Impact of Fluoride Exposure on Rat Placenta: Foetal/Placental Morphometric Alterations and Decreased Placental Vascular Density
Inorganic fluoride is a geogenic and anthropogenic contaminant widely distributed in the environment and commonly identified in contaminated...
-
Trophoblast Organoids as a Novel Tool to Study Human Placental Development and Function
The human placenta provides the site of exchange between the maternal and fetal bloodstreams, acts as an endocrine organ, and has immunological...
-
Global DNA methylation and miR-126-3p expression in Mexican women with gestational diabetes mellitus: a pilot study
BackgroundGestational diabetes mellitus (GDM), a type of diabetes that occurs for the first time during pregnancy, may predispose the development of...
-
Vaginal Microbiota Is Stable and Mainly Dominated by Lactobacillus at Third Trimester of Pregnancy and Active Childbirth: A Longitudinal Study of Ten Mexican Women
In healthy women at reproductive age, the vaginal microbiota is mainly dominated by Lactobacillus bacteria during pregnancy and non-pregnancy stages....
-
Maternal diet disrupts the placenta–brain axis in a sex-specific manner
High maternal weight is associated with detrimental outcomes in offspring, including increased susceptibility to neurological disorders such as...
