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Signification and Application of Mutator and Antimutator Phenotype-Induced Genetic Variations in Evolutionary Adaptation and Cancer Therapeutics
Mutations present a dichotomy in their implications for cellular processes. They primarily arise from DNA replication errors or damage repair...
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Is Aging an Inevitable Characteristic of Organic Life or an Evolutionary Adaptation?
AbstractAging is an evolutionary paradox. Several hypotheses have been proposed to explain it, but none fully explains all the biochemical and...
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cGAMP-activated cGAS–STING signaling: its bacterial origins and evolutionary adaptation by metazoans
The metazoan cGAMP-activated cGAS–STING innate immunity pathway is triggered in response to genomic instability and DNA damage, thereby providing...
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Deep reptilian evolutionary roots of a major avian respiratory adaptation
Vertebral ribs of the anterior thorax in extant birds bear bony prongs called uncinate processes, which improve the mechanical advantage of mm....
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An Introduction to Microbial Genomic Islands for Evolutionary Adaptation and Pathogenicity
Genomic islands (GEIs) play a vital role in the bacteria’s evolutionary adaptation and pathogenicity. GEIs are the unusual region located in the... -
Performance and evolutionary adaptation of heterogeneous wheat populations
The aim of this study was to investigate the potential of heterogeneous composite cross populations (CCPs) to increase sustainability and resilience...
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Evolutionary Conservation, Variability, and Adaptation of Type III Secretion Systems
Type III secretion (T3S) systems are complex bacterial structures used by many pathogens to inject proteins directly into the cytosol of the host...
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Deep genoty** reveals specific adaptation footprints of conventional and organic farming in barley populations—an evolutionary plant breeding approach
Sustainable food production for a growing world population will pose a central challenge in the coming decades. Organic farming is among the feasible...
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Evolutionary stamps for adaptation traced in Cervus nippon genome using reduced representation sequencing
Sika deer is indigenous to East Asia. Currently the species is extinct or are nearing the verge of extinction, in numerous places. Reduced population...
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Colonization of gut microbiota by plasmid-carrying bacteria is facilitated by evolutionary adaptation to antibiotic treatment
Multidrug-resistant plasmid-carrying bacteria are of particular clinical concern as they could transfer antibiotic resistance genes to other...
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Adaptation to climate change through dispersal and inherited timing in an avian migrant
Many organisms fail to adjust their phenology sufficiently to climate change. Studies have concentrated on adaptive responses within localities, but...
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The evolutionary drivers and correlates of viral host jumps
Most emerging and re-emerging infectious diseases stem from viruses that naturally circulate in non-human vertebrates. When these viruses cross over...
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The Evolving Evolutionary Synthesis
I review the controversy advanced by advocates of an “extended evolutionary synthesis” (EES) in the light of other controversies in evolutionary... -
Host and microbiome jointly contribute to environmental adaptation
Most animals and plants have associated microorganisms, collectively referred to as their microbiomes, which can provide essential functions. Given...
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Genomic insights into the seawater adaptation in Cyprinidae
BackgroundCyprinidae, the largest fish family, encompasses approximately 367 genera and 3006 species. While they exhibit remarkable adaptability to...
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Mycorrhizas drive the evolution of plant adaptation to drought
Plant adaptation to drought facilitates major ecological transitions, and will likely play a vital role under looming climate change. Mycorrhizas,...
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Gene birth in a model of non-genic adaptation
BackgroundOver evolutionary timescales, genomic loci can switch between functional and non-functional states through processes such as...
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Comparative genomic analyses provide new insights into evolutionary history and conservation genomics of gorillas
Genome sequencing is a powerful tool to understand species evolutionary history, uncover genes under selection, which could be informative of local...