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Degradation of deoxynivalenol by a microbial consortia C1 from duck intestine
Deoxynivalenol (DON), one of the most widespread mycotoxins in food and feed, poses a persistent health threat to humans and farm animals, and is...
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The potential of soil microbial communities to transform deoxynivalenol in agricultural soilsāa soil microcosm study
Infestation of cereal fields with toxigenic Fusarium species is identified as an environmental source for the mycotoxin deoxynivalenol (DON). During...
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Establishment of a chicken intestinal organoid culture system to assess deoxynivalenol-induced damage of the intestinal barrier function
BackgroundDeoxynivalenol (DON) is a mycotoxin that has received recognition worldwide because of its ability to cause growth delay, nutrient...
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Deoxynivalenol affects cell metabolism in vivo and inhibits protein synthesis in IPEC-1 cells
Deoxynivalenol is present in forage crops in concentrations that endanger animal welfare but is also found in cereal-based food. The amphipathic...
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Genetic map** of deoxynivalenol and fusarium damaged kernel resistance in an adapted durum wheat population
BackgroundFusarium head blight (FHB) infection results in Fusarium damaged kernels (FDK) and deoxynivalenol (DON) contamination that are downgrading...
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Efficacy of Beta vulgaris Essential Oils Against Potato Dry Rot Disease and Deoxynivalenol (DON) Mycotoxin
Potato dry rot is a global problem caused by Fusarium species. Symptoms of dry rot include wrinkled brown to black patches of tissue. Fusarium spp....
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Deoxynivalenol accumulation and detoxification in cereals and its potential role in wheatāFusarium graminearum interactions
Deoxynivalenol (DON) is a prominent mycotoxin showing significant accumulation in cereal plants during infection by the phytopathogen Fusarium...
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Estrogenic, androgenic, and genotoxic activities of zearalenone and deoxynivalenol in in vitro bioassays including exogenous metabolic activation
Zearalenone (ZEN) and deoxynivalenol (DON) and their derivatives are well-known mycotoxins, which can occur not only in crops but also in water...
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A comparison between the role of enniatins and deoxynivalenol in Fusarium virulence on different tissues of common wheat
BackgroundFusarium graminearum and Fusarium avenaceum are two of the most important causal agents of Fusarium head blight (FHB) of wheat. They can...
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Deoxynivalenol triggers the expression of IL-8-related signaling cascades and decreases protein biosynthesis in primary monocyte-derived cells
Humans and their immune system are confronted with mold-contaminated food and/or mold-contaminated air in daily life and indoor activities. This...
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Integrated management of wheat (Triticum aestivum L.) Fusarium head blight and deoxynivalenol contamination through host resistance and fungicide application in Ethiopia
Fusarium head blight (FHB) caused by Fusarium spp. is an emerging destructive wheat disease in Ethiopia. This disease significantly reduces grain...
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Ferroptosis is involved in deoxynivalenol-induced intestinal damage in pigs
BackgroundDeoxynivalenol (DON) is a widespread issue for feed and food safety, leading to animal and human health risks. The objective of this study...
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High deoxynivalenol and ergot alkaloid levels in wheat grain: effects on growth performance, carcass traits, rumen fermentation, and blood parameters of feedlot cattle
This study was designed to assess the impacts of a mixture of deoxynivalenol (DON) and ergot alkaloids (EAs) on growth performance, rumen function,...
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Identification and characterization of Achromobacter spanius P-9 and elucidation of its deoxynivalenol-degrading potential
Deoxynivalenol (DON) poses significant challenges due to its frequent contamination of grains and associated products. Microbial strategies for...
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Real-life exposure to Fusarium toxins deoxynivalenol and zearalenone triggers apoptosis and activates NLRP3 inflammasome in bovine primary theca cells
Cattle are deemed less susceptible to mycotoxins due to the limited internal exposure resulting from rumen microbiota activity. However, the...
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Glycyrrhinic acid and probiotics alleviate deoxynivalenol-induced cytotoxicity in intestinal epithelial cells
Deoxynivalenol (DON) is one of the most prevalent mycotoxin contaminants, which posing a serious health threat to animals and humans. Previous...
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Oerskovia flava sp. nov., a deoxynivalenol (DON)-degrading actinomycete isolated from the rhizosphere soil of long-term continuous crop** cucumber
The deoxynivalenol (DON)-degrading bacterium JB1-3-2 T was isolated from a rhizosphere soil sample of cucumber collected from a greenhouse located in...
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Deoxynivalenol induces m6A-mediated upregulation of p21 and growth arrest of mouse hippocampal neuron cells in vitro
Hippocampal neurons maintain the ability of proliferation throughout life to support neurogenesis. Deoxynivalenol (DON) is a mycotoxin that exhibits...
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Individual and combined effects of deoxynivalenol (DON) with other Fusarium mycotoxins on rainbow trout (Oncorhynchus mykiss) growth performance and health
This study assessed whether the toxicological effects of deoxynivalenol (DON) produced by Fusarium graminearum in rainbow trout ( Oncorhynchus mykiss )...
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Sodium butyrate alleviates deoxynivalenol-induced hepatic cholesterol metabolic dysfunction via RORĪ³-mediated histone acetylation modification in weaning piglets
BackgroundCholesterol is an essential component of lipid rafts in cell plasma membrane, which exerts a hepatoprotective role against mycotoxin...
