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The neurovascular unit and its correlation with cognitive performance in patients with cerebral small vessel disease: a canonical correlation analysis approach
Growing evidence indicates an important role of neurovascular unit (NVU) dysfunction in the pathophysiology of cerebral small vessel disease (cSVD)....
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Metabolic Networks: Weighted Gene Correlation Network Analysis
Weighted Gene Correlation Network Analysis (WGCNA) is used to build weighted gene networks representing direct interconnections among genes. This...
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Evidence for a competitive relationship between executive functions and statistical learning
The ability of the brain to extract patterns from the environment and predict future events, known as statistical learning, has been proposed to...
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RNA Double-Helix Hybridization Measured by Fluorescence Correlation Spectroscopy
RNA double-strand hybridization is a key player in gene expression regulation. Single-stranded RNA of up to 300 nucleotides forms Watson-Crick base...
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Evaluation of landscape sustainability of protected areas and identification of its correlation factors: a case study of Bei**g, China
ContextProtected areas (PAs) serve as robust safeguards for the ecological safety of urban areas, and positively affect their socioeconomic...
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DisoFLAG: accurate prediction of protein intrinsic disorder and its functions using graph-based interaction protein language model
Intrinsically disordered proteins and regions (IDPs/IDRs) are functionally important proteins and regions that exist as highly dynamic conformations...
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Fluorescence Correlation Spectroscopy and Phase Separation
A quantitative understanding of the forces controlling the assembly and functioning of biomolecular condensates requires the identification of phase...
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Multiple Traits and Genetic Correlation
This chapter introduces the concept of genetic correlation between traits. Causes of genetic correlation between traits are described: (1) pleiotropy...
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The mechanisms, regulations, and functions of histone lysine crotonylation
Histone lysine crotonylation (Kcr) is a new acylation modification first discovered in 2011, which has important biological significance for gene...
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Dissecting the role of soybean rhizosphere-enriched bacterial taxa in modulating nitrogen-cycling functions
AbstractCrop roots selectively recruit certain microbial taxa that are essential for supporting their growth. Within the recruited microbes, some...
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Colocalization by cross-correlation, a new method of colocalization suited for super-resolution microscopy
BackgroundA common goal of scientific microscopic imaging is to determine if a spatial correlation exists between two imaged structures. This is...
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Bacterial communities in cropland soils: Taxonomy and functions
Background and AimsUnderstanding microbial compositions and functions in arable soils is crucial for effective agroecosystem management. While many...
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Measuring Molecular Diffusion in Self-Organizing Xenopus Extracts by Fluorescence Correlation Spectroscopy
The cytoplasm is densely packed with macromolecules and organelles, displaying viscoelastic properties at various scales. How biochemical reactions...
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Identification of RNA structures and their roles in RNA functions
The development of high-throughput RNA structure profiling methods in the past decade has greatly facilitated our ability to map and characterize...
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Inverted U-shaped correlation between serum low-density lipoprotein cholesterol levels and cognitive functions of patients with type 2 diabetes mellitus
BackgroundLow-density lipoprotein cholesterol (LDL-C) metabolic disorder is common in individuals with diabetes. The role of LDL-C in mild cognitive...
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Prediction of lncRNA functions using deep neural networks based on multiple networks
BackgroundMore and more studies show that lncRNA is widely involved in various physiological processes of the organism. However, the functions of the...
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Biomolecular Condensates: Structure, Functions, Methods of Research
AbstractThe term “biomolecular condensates” is used to describe membraneless compartments in eukaryotic cells, accumulating proteins and nucleic...
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Cytotoxic Tph subset with low B-cell helper functions and its involvement in systemic lupus erythematosus
T peripheral helper (Tph) cells are thought to contribute to extra-follicular B cell activation and play a pathogenic role in autoimmune diseases....
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Analysis of Correlation between PRM1, STK35, and IFT27 Gene Expression Levels and Holstein Bull Semen Quality Parameters
AbstractSurveys were carried out to analyze the correlation between the mRNA expression levels of the PRM1, STK35, and IFT27 genes and the quality...
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Canonical Correlation Model for Understanding Fig (Ficus carica L.) Mislabeling Using Biochemical and Morphometric Markers
This study investigated potential mislabeling within 23 fig cultivars from northern Morocco by integrating morphometric and biochemical markers...
