Search
Search Results
-
Enzymatic and Non-enzymatic Collagen Cross-Links and Fracture Occurrence in Type 1 Diabetes Patients
Increased fracture risk in type 1 diabetes (T1D) patients is not fully captured by bone mineral density (BMD) by DXA. Advanced glycation end-products...
-
Validation of Fourier Transform Infrared Microspectroscopy for the Evaluation of Enzymatic Cross-Linking of Bone Collagen
Enzymatic cross-linking of the bone collagen is important to resist to crack growth and to increased flexural strength. In the present study, we...
-
Assessment of Collagen in Translational Models of Lung Research
The extracellular matrix (ECM) plays an important role in lung health and disease. Collagen is the main component of the lung ECM, widely used for... -
Modulation of Adhesion and Migration of NIH/3T3 Cells in Collagen Materials by Taxifolin Derivatives
AbstractOne of the urgent tasks of tissue engineering is the development of stable non-toxic materials that support cell migration during tissue...
-
Collagen piezoelectricity in osteogenesis imperfecta and its role in intrafibrillar mineralization
Intrafibrillar mineralization plays a critical role in attaining desired mechanical properties of bone. It is well known that amorphous calcium...
-
Collagen Fibrils of Various Diameters: Formation Conditions and Principles of Functioning
AbstractIn the body, collagen is one of the main proteins of the extracellular matrix that can be found in various tissues mainly in the fibrillar...
-
Tumor-associated macrophages restrict CD8+ T cell function through collagen deposition and metabolic reprogramming of the breast cancer microenvironment
Tumor progression is accompanied by fibrosis, a condition of excessive extracellular matrix accumulation, which is associated with diminished...
-
A collagen glucosyltransferase drives lung adenocarcinoma progression in mice
Cancer cells are a major source of enzymes that modify collagen to create a stiff, fibrotic tumor stroma. High collagen lysyl hydroxylase 2 (LH2)...
-
Collagen-based Mineralization of Bones, Teeth, and Other Vertebrate Skeletal Tissues
The chapter considers the structure, organization, and function of two major collagen species, type I and X collagen, and their relationship to the... -
Biomaterials Derived from Agricultural Waste: A Focus on Collagen
Heightened environmental consciousness has led scientists and researchers to seek substitutes to replace petroleum-based materials in a renewable and... -
Morphogenesis of Osteoid Structures during Cultivation of Mesenchymal Stromal Cells on Fibrillary Collagen in the Presence of Silicoaluminophosphate
Abstract—The effect of the Biosit-Sr Elkor glass-crystalline material on the early stages of morphogenesis of osteoid structures in cultures of...
-
A substrate protection approach to applying the calcium ion for improving the proteolysis resistance of the collagen
AbstractEnzymatic dehairing, as a crucial part of cleaner leather processing, has reached processive advancement with potentially replacing the...
-
Techniques to Assess Collagen Synthesis , Deposition , and Cross-Linking In Vitro
Synthesis, deposition, and cross-linking of collagen are hallmarks of fibroblast to myofibroblast differentiation. Standard methods for determining... -
Synthesis and characterization of a bovine collagen: GAG scaffold with Uruguayan raw material for tissue engineering
Tissue engineering (TE) and regenerative medicine offer strategies to improve damaged tissues by using scaffolds and cells. The use of collagen-based...
-
Exploring the Role of Serum Lysyl Oxidase (LOX) Levels and LOX Gene Polymorphism (G473A) in Diabetic Nephropathy
Diabetic Nephropathy (DN) is a leading microvascular complication of diabetes with poor prognosis. Extra cellular matrix accumulation (ECM) leading...
-
The Contribution of Perilacunar Composition and Mechanical Properties to Whole-Bone Mechanical Outcomes in Streptozotocin-Induced Diabetes
Osteocytes are the most abundant cell type in bone and remodel their local perilacunar matrix in response to a variety of stimuli and diseases. How...
-
Measurement of Collagen Cross-Links from Tissue Samples by Mass Spectrometry
All tissues contain an extracellular matrix (ECM) which is constantly and dynamically remodeled, either in physiological or pathological processes,... -
Fish Structural Proteins
Seafood is an important dietary constituent in human diet given its nutritive value and bioavailability of the nutritional components. The primary... -
Biotechnological Applications of Jellyfish-Derived Products
Jellyfish have been deemed as a viable food source for centuries, however little is known regarding its collagen and its bioactive qualities. With... -
Extracellular Matrix Alterations in Human Soleus Muscle under Conditions of Chronic Disorder of Consciousness
AbstractCritical illness myopathy (CIM) is a primary myopathy that develops in critically ill patients. Histological features of CIM include a...