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Circular Dichroism
In our analysis of how an electromagnetic radiation field interacts with electrons, we have, to this point, considered only the oscillating electric...
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Circular Dichroism (CD) Spectroscopy
Circular dichroism (CD) has been extensively used to characterize proteins, especially protein structural changes, protein–ligand interactions, and...
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Characterization of Z-DNA Using Circular Dichroism
The B-DNA to Z-DNA transition is a remarkable conformational change in DNA, which was originally observed in poly-GC DNA in the presence of high salt...
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Circular and Linear Dichroism for the Analysis of Small Noncoding RNA Properties
Useful structural information about the conformation of nucleic acids can be quickly acquired by circular and linear dichroism (CD/LD) spectroscopy....
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DichroIDP: a method for analyses of intrinsically disordered proteins using circular dichroism spectroscopy
Intrinsically disordered proteins (IDPs) are comprised of significant numbers of residues that form neither helix, sheet, nor any other canonical...
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Circular Dichroism Spectroscopy: Principle and Application
Circular dichroism spectroscopy is generally used to determine the secondary and tertiary structure of proteins. Its principle is based on...
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Magnetic Circular Dichroism in Archean Stratospheric Oxygen: Enantiomeric Excess of Amino Acids Produced in Volcanic Plumes
While there is consensus that Archean atmosphere was anoxic with O 2 pressure, p (O 2 ) <10 -6 PAL (present atmospheric level) at sea-level, evidence...
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Monitoring Real-Time Temperature Dynamics of a Short RNA Hairpin Using Förster Resonance Energy Transfer and Circular Dichroism
RNA molecules play crucial roles in gene expression regulation and cellular signaling, and these functions are governed by the formation of RNA...
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Applications of Circular Dichroism Spectroscopy in Studying Protein Folding, Stability, and Interaction
Circular dichroism (CD) spectroscopy has been extensively used to determine the structure and folding of proteins. It provides valuable information...
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Far-UV circular dichroism signatures indicate fluorophore labeling induced conformational changes of penetratin
Fluorescent labeling is a broadly utilized approach to assess in vitro and in vivo behavior of biologically active, especially cell-penetrating and...
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Design of stable circular permutants of the GroEL chaperone apical domain
Enhancing protein stability holds paramount significance in biotechnology, therapeutics, and the food industry. Circular permutations offer a...
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Beyond the US-SOMO-AF database: a new website for hydrodynamic, structural, and circular dichroism calculations on user-supplied structures
At the 25th International Analytical Ultracentrifugation Workshop and Symposium, we described the recent implementation of the UltraScan SOlution...
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Circular permutation at azurin’s active site slows down its folding
Circular permutation (CP) is a technique by which the primary sequence of a protein is rearranged to create new termini. The connectivity of the...
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Effect of setting data collection parameters on the reliability of a circular dichroism spectrum
Circular dichroism (CD) spectroscopy is a well-established biophysical technique used to investigate the structure of molecules. The analysis of a...
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BeStSel: From Secondary Structure Analysis to Protein Fold Prediction by Circular Dichroism Spectroscopy
Far-UV circular dichroism (CD) spectroscopy is a classical method for the study of the secondary structure of polypeptides in solution. It has been...
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Circular Dichroism to Probe the Synthesis, Transfer, and Stability of Fe-S Clusters
All Fe-S proteins are characterized by distinctive circular dichroism (CD) features in the visible region of the spectrum due to chiral interaction...
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Circular dichroism and resonance Raman spectroscopies of bacteriochlorophyll b-containing LH1-RC complexes
The core light-harvesting complexes (LH1) in bacteriochlorophyll (BChl) b -containing purple phototrophic bacteria are characterized by a...
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How accurate is circular dichroism-based model validation?
Circular dichroism (CD) spectroscopy is highly sensitive to the secondary structure (SS) composition of proteins. Several methods exist to either...
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Mitigation of the Deleterious Effect of Heavy Metals on the Conformational Stability of Ubiquitin through Osmoprotectants
The Ubiquitin-Proteasome System (UPS) is important in protein homeostasis and is involved in many cell processes. UPS’s wide range of regulatory...
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Chiroptical Properties of Z-DNA Using Ionic Porphyrins and Metalloporphyrins
The non-covalent interaction of achiral porphyrins with nucleic acids has been extensively studied, and various macrocycles have been indeed utilized...