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A modular systems biology analysis of cell cycle entrance into S-phase
A modular systems biology approach to the study of the cell cycle of the budding yeast Saccharomyces cerevisiae is presented. Literature on the...
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FGF19 induces the cell cycle arrest at G2-phase in chondrocytes
Fibroblast growth factor 19 (FGF19) has appeared as a new possible avenue in the treatment of skeletal metabolic disorders. However, the role of...
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The Distribution of B16 Melanoma Cells in Cell-Cycle Phases under the Influence of Dacarbazine
AbstractOne mechanism for the development of drug resistance in tumor cells is a reversible transition to the resting phase (G 0 ) of the cell cycle....
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Cell Cycle Map** Using Multiplexed Immunofluorescence
The development of technologies that allow measurement of the cell cycle at the single-cellSingle-cell level has revealed novel insights into the...
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Mouse Models of Cell Cycle Regulators: New Paradigms
In yeast, a single cyclin-dependent kinase (Cdk) is able to regulate diverse cell cycle transitions (S and M phases) by associating with multiple...
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Cell Cycle
The basis for reproduction of all organisms is a process called the cell cycle [75]. As the name implies, the cell cycle is an iterative, periodic...
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Analysis of Cell Cycle and DNA Compaction Dependent Subnuclear Distribution of Histone Marks
In eukaryotes, the organization of DNA wrapped around histones regulates DNA-dependent processes. Changes in epigenetic modifications modulate the...
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Cell cycle-specific phase separation regulated by protein charge blockiness
Dynamic morphological changes of intracellular organelles are often regulated by protein phosphorylation or dephosphorylation
1 –6 . Phosphorylation...
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Liquiritigenin Induces Cell Cycle Arrest and Apoptosis in Lung Squamous Cell Carcinoma
Liquiritigenin (LQ), as a dihydroflavone monomer compound extracted from Glycyrrhiza uralensis Fisch, has been demonstrated to show anti-tumor...
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Cancer radioresistance is characterized by a differential lipid droplet content along the cell cycle
BackgroundCancer radiation treatments have seen substantial advancements, yet the biomolecular mechanisms underlying cancer cell radioresistance...
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The interplay between cell wall integrity and cell cycle progression in plants
Plant cell walls are dynamic structures that play crucial roles in growth, development, and stress responses. Despite our growing understanding of...
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The Centrosome Cycle within the Cell Cycle
The synchronized distribution of centrosomal and genetic materials to the dividing daughter cells is critically important and depends on precisely...
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A novel auxin-inducible degron system for rapid, cell cycle-specific targeted proteolysis
The discrimination of protein biological functions in different phases of the cell cycle is limited by the lack of experimental approaches that do...
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Real-Time Cell Cycle Imaging in a 3D Cell Culture Model of Melanoma, Quantitative Analysis, Optical Clearing, and Mathematical Modeling
Aberrant cell cycle progression is a hallmark of solid tumors. Therefore, cell cycle analysis is an invaluable technique to study cancer cell...
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A comprehensive review of computational cell cycle models in guiding cancer treatment strategies
This article reviews the current knowledge and recent advancements in computational modeling of the cell cycle. It offers a comparative analysis of...
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The cell cycle, autophagy, and cell wall integrity pathway jointly governed by MoSwe1 in Magnaporthe oryzae
The cell cycle is pivotal to cellular differentiation in plant pathogenic fungi. Cell wall integrity (CWI) signaling plays an essential role in...
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Selective pks+ Escherichia coli strains induce cell cycle arrest and apoptosis in colon cancer cell line
pks+ Escherichia coli ( E. coli) triggers genomic instability in normal colon cells which leads to colorectal cancer (CRC) tumorigenesis. Previously,...
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Short cell cycle duration is a phenotype of human epidermal stem cells
BackgroundA traditional view is that stem cells (SCs) divide slowly. Meanwhile, both embryonic and pluripotent SCs display a shorter cell cycle...
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Titanium Dioxide Nanoparticles Induce Cell Cycle Arrest and Apoptosis through Inhibiting PI3K/AKT/mTOR Pathway in Spermatogonia
Titanium dioxide nanoparticles (TiO 2 NPs) can result in the reduction of sperm numbers, but the mechanisms have not been well elucidated. The purpose...
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Cell Cycle-Related Clinical Applications
The cell cycle is a highly regulated and orchestrated mechanism of life that ensures successive division of a cell and precise replication of...