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Effect of cardiopulmonary bypass on plasma and erythrocytes oxylipins
BackgroundOxylipins, the oxidative metabolites of polyunsaturated fatty acids (PUFAs), serve as key mediators of oxidative stress, inflammatory...
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Dynamic Changes in the Immune Status and Biochemical Blood Markers in Patients after Cardiac Surgery with Cardiopulmonary Bypass
AbstractA general nonspecific adaptive reaction, stress develo** during the sequential implementation of the stages “anxiety,” “resistance,” and...
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Ferroptosis Exists in Ischemia Reperfusion Injury after Cardiac Surgery with Cardiopulmonary Bypass
Ischemia-reperfusion (IR) injury commonly arises during cardiac surgery involving Cardiopulmonary Bypass (CPB), and it has relationship with...
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Circulating small extracellular vesicle-encapsulated SEMA5A-IT1 attenuates myocardial ischemia–reperfusion injury after cardiac surgery with cardiopulmonary bypass
Cardiomyocyte injury is a common complication during cardiac surgery with cardiopulmonary bypass (CPB). Studies have shown that circulating small...
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Regional lung metabolic profile in a piglet model of cardiopulmonary bypass with circulatory arrest
IntroductionAcute lung injury is common following cardiopulmonary bypass and deep hypothermic circulatory arrest for congenital heart surgery with...
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Trace Element Status and Postoperative Morbidity After On-pump Coronary Artery Bypass Surgery
Trace elements are essential micronutrients that take part in most antioxidant reactions in the body. In this study, we evaluated the levels of...
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Neurophysiological Parameters in Patients after Coronary Bypass Grafting Depending on the Success of Dual-Task Rehabilitation
Abstract —The effect of dual-task cognitive training on neurophysiological parameters of patients with postoperative cognitive dysfunction (POCD) in...
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The Crosstalk between Coronary Artery Bypass Grafting and miRNAs
AbstractMiRNAs, which are small noncoding RNA molecules that regulate over 60% of genes, modulate gene expression. MiRNAs have been implicated in...
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Endothelial extracellular vesicles induce acute lung injury via follistatin-like protein 1
Cardiopulmonary bypass has been speculated to elicit systemic inflammation to initiate acute lung injury (ALI), including acute respiratory distress...
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Activation of kynurenine pathway of tryptophan metabolism after infant cardiac surgery with cardiopulmonary bypass: a prospective cohort study
BackgroundSerum kynurenic acid is associated with poor outcomes after infant cardiopulmonary bypass (CPB), but comprehensive map** of the...
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Concentration of circulating microparticles: a new biomarker of acute heart failure after cardiac surgery with cardiopulmonary bypass
Acute heart failure (AHF) is a severe complication after cardiac surgery with cardiopulmonary bypass (CPB). Although some AHF biomarkers have been...
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Endothelial colony-forming cells reduced the lung injury induced by cardiopulmonary bypass in rats
BackgroundCardiopulmonary bypass (CPB) results in severe lung injury via inflammation and endothelial injury. The aim of this study was to evaluate...
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Using Digital Biomarkers for Objective Assessment of Perfusionists’ Workload and Acute Stress During Cardiac Surgery
The cardiac operating room (OR) is a high-risk, high-stakes environment inserted into a complex socio-technical healthcare system. During...
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Assessment of left ventricular tissue mitochondrial bioenergetics in patients with stable coronary artery disease
Recurrent myocardial ischemia can lead to left ventricular (LV) dysfunction in patients with coronary artery disease (CAD). In this observational...
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Effects of Perioperative Zinc Supplementation on Copper Circulating Levels and Expression of Metallothionein and Copper Antioxidant Chaperone-1 in Leukocytes in Patients Undergoing CABG Surgery
The use of zinc supplement may have a negative effect on copper status. The objective of this study was to evaluate the effect of zinc and vitamin E...
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Surgical Methods for Cardiac Gene Delivery in Large Animals
This chapter describes main strategies of surgical gene delivery in large animals. Existing methods of cardiac gene transfer can be classified by the...
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History of Heart Valve Repair
The history of open-heart surgery allowing for valve repair or replacement is quite amazing. Both the patients and surgeon had immense courage to be...
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Evaluation of the usefulness of determining the level of selected inflammatory biomarkers and resistin concentration in perivascular adipose tissue and plasma for predicting postoperative atrial fibrillation in patients who underwent myocardial revascularisation
BackgroundThe development of coronary artery disease (CAD) is related to the impaired quantity and composition of inflammatory proteins found in...
