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Analyses of oxidative DNA damage among coal vendors via single cell gel electrophoresis and quantification of 8-hydroxy-2’-deoxyguanosine
Looking at the development status of Nigeria and other develo** nations, most low-income and rural households often use coal as a source of energy...
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Exogenous 8-hydroxydeoxyguanosine attenuates doxorubicin-induced cardiotoxicity by decreasing pyroptosis in H9c2 cardiomyocytes
Doxorubicin (DOX), which is widely used in cancer treatment, can induce cardiomyopathy. One of the main mechanisms whereby DOX induces cardiotoxicity...
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Effect of Fluoride on the Expression of 8-Hydroxy-2′-Deoxyguanosine in the Blood, Kidney, Liver, and Brain of Rats
Excessive exposure of fluoride not only leads to damage on bone, but also has an adverse effect on soft tissues. Oxidative DNA damage induced by...
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Neurochemical Research of LOXBlock-1 and ZnSO4 against Neurodegenerative Damage Induced by Amyloid Beta(1-42)
Synaptosomes offer an intriguing ex vivo model system for investigating the molecular mechanisms of neurodegenerative processes. Lipoxygenases...
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Protective Effect of Myricetin Against Experimentally Induced Torsion in Rats
AbstractTesticular torsion causes ischemia and free radical formation by obstructing vascular flow caused by complete or partial rotation of the...
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Association of functional superoxide gene polymorphism with chlamydia trachomatis-associated recurrent spontaneous abortion
BackgroundOxidative stress generated by Chlamydia trachomatis infection is associated with reproductive complications such as recurrent spontaneous...
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Evaluated periodontal tissues and oxidative stress in rats with neuropathic pain-like behavior
BackgroundOxidative stress has a critical effect on both persistent pain states and periodontal disease. Voltage-gated sodium NaV1.7 (SCN9A), and...
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Duchenne muscular dystrophy progression induced by downhill running is accompanied by increased endomysial fibrosis and oxidative damage DNA in muscle of mdx mice
Duchenne muscular dystrophy (DMD) is characterized by progressive muscle necrosis. One of the major challenges for prescribing physical...
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Myometrial oxidative stress drives MED12 mutations in leiomyoma
BackgroundMore than 70% of leiomyomas (LM) harbor MED12 mutations, primarily in exon 2 at c.130-131(GG). The cause of MED12 mutations in myometrial...
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Repeated controlled ovarian stimulation-induced ovarian and uterine damage in mice through the PI3K/AKT signaling pathway
The effects of repeated controlled ovarian stimulation (COS) on the female reproductive system are still controversial. This study investigated the...
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Elevated Oxidized LDL Level is Associated with Systematic Coronary Risk Evaluation (SCORE2) High-Risk Prediction Algorithm: A Preliminary Study
Estimation of cardiovascular (CV) individual risk over a 10 year period was provide benefit most from preventive action in individual at high risk of...
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Delayed effects of radiation in adipose tissue reflect progenitor damage and not cellular senescence
The pathogenesis of many age-related diseases is linked to cellular senescence, a state of inflammation-inducing, irreversible cell cycle arrest. The...
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Boron Compound–Based Treatments Against Multidrug-Resistant Bacterial Infections in Lung Cancer In Vitro Model
Multidrug-resistant bacteria is one of the most important public health problems. Increasing rates of antibacterial resistance also affect the...
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Boric Acid and Borax Protect Human Lymphocytes from Oxidative Stress and Genotoxicity Induced by 3-Monochloropropane-1,2-diol
3-chloro-1,2-propanediol (3-MCPD) is a member of the group of pollutants known as chloropropanols and is considered a genotoxic carcinogen. Due to...
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Eucalyptol Protects against Cisplatin-Induced Liver Injury in Rats
AbstractEucalyptol (1,8-cineole), a terpenoid oxide, is known as the main component of eucalyptus essential oils. The antimicrobial,...
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Toxic Effects of Lactococcus garvieae, Staphylococcus epidermidis, and Bacillus subtilis Bacteria on the Physiology of Rainbow Trout
AbstractIn the trout production establishments all over the world, the most common pathogenic bacterial factors are increasing. Therefore, in this...
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Downhill running induced DNA damage enhances mitochondrial membrane permeability by facilitating ER-mitochondria signaling
To observe whether downhill running can lead to DNA damage in skeletal muscle cells and changes in mitochondrial membrane permeability and to explore...
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Comparative Analysis of Epigallocatechin-3-Gallate and TNF-Alpha Inhibitors in Mitigating Cisplatin-Induced Pancreatic Damage Through Oxidative Stress and Apoptosis Pathways
Oxidative stress and inflammation caused by cisplatin, which is frequently used in the treatment of many cancers, damage healthy tissues as well as...
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Isoquercitrin alleviates OGD/R-induced oxidative stress and impaired mitochondrial biogenesis in SH-SY5Y cells via the NRF1/TFAM pathway
Isoquercitrin (ISO) is a traditional Chinese medicine extract, that has been found to possess potent neuroprotective properties. However, its precise...
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Linagliptin ameliorates tacrolimus-induced renal injury: role of Nrf2/HO-1 and HIF-1α/CTGF/PAI-1
BackgroundTacrolimus (TAC) is a frequently used immunosuppressive medication in organ transplantation. However, its nephrotoxic impact limits its...
