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Converting cell death into senescence by PARP1 inhibition improves recovery from acute oxidative injury
Excessive amounts of reactive oxygen species (ROS) lead to macromolecular damage and high levels of cell death with consequent pathological sequelae....
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Signaling Pathways in Plant Responses to Abiotic Stress
Recent scientific advancements have significantly improved our understanding of plant signaling pathways under abiotic stress. However, further... -
Number of recurrences is significantly associated with the post-acute pancreatitis diabetes mellitus in a population with hypertriglyceridemic acute pancreatitis
BackgroundTwenty-three percent of patients are diagnosed with diabetes mellitus after the first episode of acute pancreatitis. The incidence of...
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Protective effect of apelin-13 on ventilator-induced acute lung injury
BackgroundMechanical Ventilation (MV) is an essential mechanism of life support in the clinic. It may also lead to ventilator-induced acute lung...
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Oxidative Stress, Endoplasmic Reticulum Stress and Apoptosis in the Pathology of Alzheimer’s Disease
Alzheimer’s disease (AD) accounts for a major statistic among the class of neurodegenerative diseases. A number of mechanisms have been identified in...
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Regulation of cultured coral endosymbiont photophysiology by alternate heat stress protocols
Unlocking how coral endosymbionts (Symbiodiniaceae) regulate the susceptibility of corals to thermal stress-induced bleaching has been the focus of...
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Role of subcytotoxic stress in tissue ageing
Most commonly stress-induced premature senescence (SIPS) is defined as the long-term effects of subcytotoxic stress on proliferative cell types,... -
Effects of acute hypoxia on nutrient metabolism and physiological function in turbot, Scophthalmus maximus
Acute hypoxia is a common stress in aquaculture, and causes energy deficiency, oxidative damage and death in fish. Many studies have confirmed that...
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Boric Acid Alleviates Lipopolysaccharide-Induced Acute Lung Injury in Mice
Acute lung injury (ALI) poses a significant medical challenge due to its widespread occurrence and high mortality rates. Despite extensive efforts,...
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Knockdown of ELF4 aggravates renal injury in ischemia/reperfusion mice through promotion of pyroptosis, inflammation, oxidative stress, and endoplasmic reticulum stress
BackgroundRenal ischemia/reperfusion (I/R) injury is a major cause of acute kidney injury (AKI). Dysfunction of E74-like ETS transcription factor 4...
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Detecting Stress Granules in Drosophila Neurons
Stress granules (SGs) are cytoplasmic ribonucleoprotein condensates that dynamically and reversibly assemble in response to stress. They are thought... -
Boric Acid Affects Cell Proliferation, Apoptosis, and Oxidative Stress in ALL Cells
T-cell acute lymphoblastic leukemia (T-ALL) is a type of acute lymphoblastic leukemia from early T-cell progenitors. Interest grows in creating less...
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ARRB1 suppresses the activation of hepatic macrophages via modulating endoplasmic reticulum stress in lipopolysaccharide-induced acute liver injury
Acute liver injury (ALI) caused by multiple inflammatory responses is a monocyte-/macrophage-mediated liver injury that is associated with high...
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The role of fatty acid metabolism in acute lung injury: a special focus on immunometabolism
Reputable evidence from multiple studies suggests that excessive and uncontrolled inflammation plays an indispensable role in mediating, amplifying,...
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Downregulation of HNF4A enables transcriptomic reprogramming during the hepatic acute-phase response
The hepatic acute-phase response is characterized by a massive upregulation of serum proteins, such as haptoglobin and serum amyloid A, at the...
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Real-time glucose monitoring biosensor system assesses the effects of different environmental light colors on Nile tilapia stress response
Nile tilapia Oreochromis niloticus is an important aquaculture species worldwide, and understanding its behavior and growth performance under...
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Climate Change and Stress Response in Teleost
Fish being ectotherms and in direct contact with water are directly affected by climate change-induced hydrogeological changes and demonstrate a... -
Endothelial cell dynamics in sepsis-induced acute lung injury and acute respiratory distress syndrome: pathogenesis and therapeutic implications
Sepsis, a prevalent critical condition in clinics, continues to be the leading cause of death from infections and a global healthcare issue. Among...
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Research progress of post-acute sequelae after SARS-CoV-2 infection
SARS-CoV-2 has spread rapidly worldwide and infected hundreds of millions of people worldwide. With the increasing number of COVID-19 patients...
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Astaxanthin supplementation enhances low-temperature stress tolerance, immune-related genes, and resistance to Vibrio parahaemolyticus in Whiteleg Shrimp Penaeus vannamei
Whiteleg shrimp Penaeus vannamei , a highly valuable commercial species in aquaculture, is known to be susceptible to environmental stressors. In this...