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Serum Glycome as a Diagnostic and Prognostic Factor in Gestational Diabetes Mellitus
AbstractGestational diabetes mellitus (GDM) is a risk factor for both mother and fetus/neonate during and after the pregnancy. Inconsistent protocols...
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Association between the expression of TLR4, TLR2, and MyD88 with low-grade chronic inflammation in individuals with metabolically healthy obesity
BackgroundAmong the Toll-like receptors (TLR) that are dependent of myeloid response protein (MyD88), the TLR4 and TLR2 are directly associated with...
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Exploring the association of FTO rs9939609 and SIRT1 rs7069102 genetic variants with obesity: A case–control study in a sample of Pakistani population
Disturbances in energy homeostasis may result in positive energy balance and excessive body weight. Susceptibility to this imbalance is primarily...
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Association between atherogenic index of plasma and coronary artery calcification progression in Korean adults
BackgroundDyslipidemia is a well-known risk factor for cardiovascular disease (CVD). Recently, atherogenic index of plasma (AIP) has been proposed as...
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Serum Ferritin Levels Are Associated with Adipose Tissue Dysfunction-Related Indices in Obese Adults
Iron overload is associated with type 2 diabetes and metabolic syndrome. However, little is known about the role of iron status on adipose tissue. We...
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Composite lipid indices in patients with obstructive sleep apnea: a systematic review and meta-analysis
BackgroundOne of the most prevalent sleep disorders affecting the individual’s daily life is obstructive sleep apnea (OSA), for which obesity is a...
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High remnant cholesterol level is relevant to diabetic retinopathy in type 2 diabetes mellitus
BackgroundDiabetic retinopathy (DR) is the primary oculopathy causing blindness in diabetic patients. Currently, there is increasing interest in the...
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Evaluation of Sampson equation for LDL-C in acute coronary syndrome patients: a Chinese population-based cohort study
ObjectiveLow-density lipoprotein cholesterol (LDL-C) is an important cardiovascular disease marker that is used to estimate the risk of acute...
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Pancreatic β-Cell Apoptosis in Normoglycemic Rats is Due to Mitochondrial Translocation of p53-Induced by the Consumption of Sugar-Sweetened Beverages
Overstimulation of pancreatic β-cells can lead to dysfunction and death, prior to the clinical manifestations of type 2 diabetes (T2D). The excessive...
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The association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and suicidal ideation in adults: a population-based study in the United States
BackgroundThe ratio of non-high-density lipoprotein cholesterol (non-HDL-C) to high-density lipoprotein cholesterol (HDL-C) (NHHR) serves as a...
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Sex-related differences in the hypertriglyceridemic-waist phenotype in association with hyperuricemia: a longitudinal cohort study
BackgroundThere is limited longitudinal evidence supporting the association between the hypertriglyceridemic-waist (HTGW) phenotype and...
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Triglyceride and glucose (TyG) index as a predictor of incident hypertension: a 9-year longitudinal population-based study
BackgroundHypertension and the triglyceride and glucose index both have been associated with insulin resistance; however, the longitudinal...
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Co-administration of HAART and antikoch triggers cardiometabolic dysfunction through an oxidative stress-mediated pathway
BackgroundAntikoch and highly active anti-retroviral therapy are effective drugs in the management of tuberculosis and Human Immunodeficiency Virus,...
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Association between rs3088440 (G > A) polymorphism at 9p21.3 locus with the occurrence and severity of coronary artery disease in an Iranian population
BackgroundSeveral genome-wide association studies showed that a series of genetic variants located at the chromosome 9p21 locus are strongly...
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Superficial Femoral Artery Calcification Is a Novel Risk Factor of Microvascular Complications in T2DM Patients
Microvascular complications are prevalent in patients with type 2 diabetes mellitus (T2DM), resulting in increased risk of cardiovascular mortality....
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Global DNA methylation and telomere length as markers of accelerated aging in people living with HIV and non-alcoholic fatty liver disease
Metabolic-dysfunction-associated fatty liver disease (MAFLD) is a comorbidity that generally increases in people living with HIV (PLWH). This...
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Adiposity mediates the association between whole grain consumption, glucose homeostasis and insulin resistance: findings from the US NHANES
BackgroundGrowing evidence suggests an inverse association between whole grain (WG) consumption and insulin resistance (IR) or inflammation. However,...
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The triglyceride and glucose index (TyG) is an effective biomarker to identify nonalcoholic fatty liver disease
BackgroundThe triglyceride and glucose index (TyG) has been proposed as a marker of insulin resistance. We aimed to investigate the ability of TyG,...
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An insight into the mechanisms of COVID-19, SARS-CoV2 infection severity concerning β-cell survival and cardiovascular conditions in diabetic patients
A significantly high percentage of hospitalized COVID-19 patients with diabetes mellitus (DM) had severe conditions and were admitted to ICU. In this...
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Age-related and gender-stratified differences in the association between high triglyceride and risk of hyperuricemia
BackgroundElevated serum uric acid is commonly associated with high triglyceride. However, the relation of triglyceride and hyperuricemia in...
