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Effects of hormones on intestinal stem cells
The maintenance of intestinal renewal and repair mainly depends on intestinal stem cells (ISCs), which can also contribute to the growth of...
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Circ-0075305 hinders gastric cancer stem cells by indirectly disrupting TCF4–β-catenin complex and downregulation of SOX9
CircRNAs are covalently closed, single-stranded RNA that form continuous loops and play a crucial role in the initiation and progression of tumors....
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METTLing in Stem Cell and Cancer Biology
The methyltransferase-like (METTL) family is a diverse group of methyltransferases that can methylate nucleotides, proteins, and small molecules....
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YAP is required for prostate development, regeneration, and prostate stem cell function
Prostate development and regeneration depend on prostate stem cell function, the delicate balance of stem cell self-renewal and differentiation....
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DMRTA2 supports glioma stem-cell mediated neovascularization in glioblastoma
Glioblastoma (GBM) is the most common and lethal brain tumor in adults. Due to its fast proliferation, diffusive growth and therapy resistance...
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Umbilical cord-derived mesenchymal stem cell sheets transplanted subcutaneously enhance cell retention and survival more than dissociated stem cell injections
BackgroundHuman umbilical cord-derived mesenchymal stem cell (hUC-MSC) sheets have recently attracted attention as an alternative approach to...
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Temporal changes in colonization levels of Ustilago esculenta in different parts of Zizania latifolia plants competent and incompetent for stem gall formation
Zizania latifolia plants infected with the basidiomycete fungus Ustilago esculenta develop an edible stem gall, called makomotake in Japan. In our...
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Challenges and perspectives of heart repair with pluripotent stem cell-derived cardiomyocytes
Here we aim at providing a concise but comprehensive overview of the perspectives and challenges of heart repair with pluripotent stem cell-derived...
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Preclinical Research of Stem Cells: Challenges and Progress
In recent years, great breakthroughs have been made in basic research and clinical applications of stem cells in regenerative medicine and other...
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Biomechanical, biophysical and biochemical modulators of cytoskeletal remodelling and emergent stem cell lineage commitment
Across complex, multi-time and -length scale biological systems, redundancy confers robustness and resilience, enabling adaptation and increasing...
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Menstrual blood-derived endometrial stem cell, a unique and promising alternative in the stem cell-based therapy for chemotherapy-induced premature ovarian insufficiency
Chemotherapy can cause ovarian dysfunction and infertility since the ovary is extremely sensitive to chemotherapeutic drugs. Apart from the...
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Extracellular matrix-induced signaling pathways in mesenchymal stem/stromal cells
The extracellular matrix (ECM) is a crucial component of the stem cell microenvironment, or stem-cell niches, and contributes to the regulation of...
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Neural Stem Cells
The introduction of neural stem cells (NSCs) from adult mouse brains by Brent Reynold and Samuel Swiss in 1992 not only paved the way for in vitro...
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Neural Stem Cells
The introduction of neural stem cells (NSCs) from adult mouse brains by Brent Reynold and Samuel Swiss in 1992 not only paved the way for in vitro...
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Mitochondria in Mesenchymal Stem Cells: Key to Fate Determination and Therapeutic Potential
Mesenchymal stem cells (MSCs) have become popular tool cells in the field of transformation and regenerative medicine due to their function of cell...
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Live Imaging of the Drosophila Testis Stem Cell Niche
Live imaging of adult tissue stem cell niches provides key insights into the dynamic behavior of stem cells, their differentiating progeny, and their...
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The Role of Ubiquitin–Proteasome System in the Biology of Stem Cells
AbstractSelective degradation of cellular proteins by the ubiquitin–proteasome system (UPS) is one of the key regulatory mechanisms in eukaryotic...
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Asymmetric division of stem cells and its cancer relevance
Asymmetric division is a fundamental process for generating cell diversity and maintaining the stem cell population. During asymmetric division,...
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Current Progress in Stem Cell Therapy for Male Infertility
Infertility has become one of the most common issues worldwide, which has negatively affected society and infertile couples. Meanwhile, male...
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Clinical Trials with Stem Cell-Derived Insulin-Producing Cells
Because of the real-time physiological glucose sensing and synchronized insulin secretion, the replacement of β-cell mass through transplantation has...