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Global freshwater mollusc invasion: pathways, potential distribution, and niche shift
Molluscs are the second largest and most speciose invertebrate phylum after Arthropoda. There are around 7000 freshwater molluscs that play an...
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Multilayer networks of plasmid genetic similarity reveal potential pathways of gene transmission
Antimicrobial resistance (AMR) is a significant threat to public health. Plasmids are principal vectors of AMR genes, significantly contributing to...
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Mature neurons from iPSCs unveil neurodegeneration-related pathways in mucopolysaccharidosis type II: GSK-3β inhibition for therapeutic potential
Mucopolysaccharidosis (MPS) type II is caused by a deficiency of iduronate-2-sulfatase and is characterized by the accumulation of glycosaminoglycans...
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Whole exome sequencing of 28 families of Danish descent reveals novel candidate genes and pathways in developmental dysplasia of the hip
Developmental dysplasia of the hip (DDH) is a common condition involving instability of the hip with multifactorial etiology. Early diagnosis and...
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Toward Sustainable Biological and Environmental Policies in Africa
The African continent is endowed with significant biodiversity and environmental resources, including terrestrial and aquatic species, water bodies,...
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Survival-related genes are diversified across cancers but generally enriched in cancer hallmark pathways
BackgroundPan-cancer studies have disclosed many commonalities and differences in mutations, copy number variations, and gene expression alterations...
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Dysregulation of a lncRNA within the TNFRSF10A locus activates cell death pathways
TNFRSF10A (tumor necrosis factor receptor superfamily member 10A) encodes a cell surface receptor protein involved in apoptotic, necroptotic, and...
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Elucidating gene expression patterns across multiple biological contexts through a large-scale investigation of transcriptomic datasets
Distinct gene expression patterns within cells are foundational for the diversity of functions and unique characteristics observed in specific...
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Proteo-transcriptomic profiles reveal key regulatory pathways and functions of LDHA in the ovulation of domestic chickens (Gallus gallus)
BackgroundIn poultry, the smooth transition of follicles from the preovulatory-to-postovulatory phase impacts egg production in hens and can benefit...
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Novel complete methanogenic pathways in longitudinal genomic study of monogastric age-associated archaea
BackgroundArchaea perform critical roles in the microbiome system, including utilizing hydrogen to allow for enhanced microbiome member growth and...
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Signaling Pathways in Trans-differentiation of Mesenchymal Stem Cells: Recent Advances
Mesenchymal stem cells are a group of multipotent cells that can be induced to differentiate into other cell types. The cells fate is decided by...
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Towards industrial biological hydrogen production: a review
Increased production of renewable energy sources is becoming increasingly needed. Amidst other strategies, one promising technology that could help...
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Dynamic antagonism between key repressive pathways maintains the placental epigenome
DNA and Histone 3 Lysine 27 methylation typically function as repressive modifications and operate within distinct genomic compartments. In mammals,...
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Regulation in Biological Systems
Any processes which occur in thermodynamically open systems must be automatically regulated if they are to maintain a steady state. Note that there...
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Primitive macrophages induce sarcomeric maturation and functional enhancement of develo** human cardiac microtissues via efferocytic pathways
Yolk sac macrophages are the first to seed the develo** heart; however, owing to a lack of accessible tissue, there is no understanding of their...
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Date pomace polysaccharide: ultrasonic-assisted deep eutectic solvent extraction, physicochemical properties, biological activities, gut microbiota modulation, and rheological properties
BackgroundThis study utilized ultrasonication-assisted green extraction techniques to explore the physicochemical, rheological, biological, and...
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MicroRNA signatures differentiate types, grades, and stages of breast invasive ductal carcinoma (IDC): miRNA-target interacting signaling pathways
BackgroundInvasive ductal carcinoma (IDC) is the most common form of breast cancer which accounts for 85% of all breast cancer diagnoses....
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Shared genetic architectures of subjective well-being in East Asian and European ancestry populations
Subjective well-being (SWB) has been explored in European ancestral populations; however, whether the SWB genetic architecture is shared across...
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Reproduction-associated pathways in females of gibel carp (Carassius gibelio) shed light on the molecular mechanisms of the coexistence of asexual and sexual reproduction
Gibel carp ( Carassius gibelio ) is a cyprinid fish that originated in eastern Eurasia and is considered as invasive in European freshwater ecosystems....
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