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Advances in Medical Imaging for Wound Repair and Regenerative Medicine
Adult mammalian wounds commonly heal through the process of repair and leave a permanent mark—the scar. Scars typically jeopardize normal organ...
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Precision regenerative medicine
BackgroundPrecision or individualized medicine is increasingly pervasive across medical and surgical disciplines. However, the concept has not been...
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Adult Stem Cell Therapy as Regenerative Medicine for End-Stage Liver Disease
The increased incidence of end-stage liver disease (ESLD) causes a major burden on the global health system and population health. Liver...
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IL-6 coaxes cellular dedifferentiation as a pro-regenerative intermediate that contributes to pericardial ADSC-induced cardiac repair
BackgroundCellular dedifferentiation is a regenerative prerequisite that warrants cell cycle reentry and appropriate mitotic division during de novo...
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Regenerative Potential of Human Breast Milk: A Natural Reservoir of Nutrients, Bioactive Components and Stem cells
Human milk is a complex fluid that contains carbohydrates, lipids, proteins, and other bioactive molecules (immunoglobulins, lactoferrin, human milk...
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GMP-Compliant Mesenchymal Stem Cell-Derived Exosomes for Cell-Free Therapy in Cancer
Cancer is categorized as one of the life-threatening disease in the world, which has recently been associated with a significant increase in the...
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Insights of CRISPR-Cas systems in stem cells: progress in regenerative medicine
Regenerative medicine, a therapeutic approach using stem cells, aims to rejuvenate and restore the normalized function of the cells, tissues, and...
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MSC-Derived Exosomes: Advances in Cell-Free Therapy
Mesenchymal stem cells (MSCs)Mesenchymal stem cells (MSCs) are a rich source of bioactive molecules, which they secrete as a part of their paracrine...
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Exosome-Based Cell-Free Therapy in Regenerative Medicine for Myocardial Repair
Exosomes in cardiovascular theranostics are gaining popularity due to their immense diagnostic and therapeutic potential generally ascribed to their...
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Exosome-Based Cell-Free Therapy in Regenerative Medicine for Myocardial Repair
Exosomes in cardiovascular theranostics are gaining popularity due to their immense diagnostic and therapeutic potential generally ascribed to their...
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Immunological considerations and challenges for regenerative cellular therapies
The central goal of regenerative medicine is to replace damaged or diseased tissue with cells that integrate and function optimally. The capacity of...
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Induced Pluripotent Stem Cells and Allogeneic Mesenchymal Stem Cell Therapy in Cardiovascular Diseases
Cell- and gene-based therapies form one of the pillars of regenerative medicine. This chapter reviews the recent progress in applying advanced...
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Osteochondral Tissue Engineering Dilemma: Scaffolding Trends in Regenerative Medicine
Orthopedic surgeons face a lot of difficulties in managing and repairing osteochondral defects. Damaged articular cartilage and the subchondral bone...
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Expression of immunomodulatory and tissue regenerative biomarkers in human dental pulp derived-mesenchymal stem cells treated with curcumin: an in vitro study
BackgroundHuman Dental pulp derived-mesenchymal stem cells (hDP-MSCs) have the capability of selfrenewal, multipotency, as well as immunosuppressive...
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Role of Polymeric Nanomaterial in Regenerative Medicine and Stem Cell Biology
The combination of nanoparticles (NPs) and stem cells have been extensively investigated in regenerative medicine. Different types of NPs have been...
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Latest Advances in Mesenchymal Stem Cell-Based Therapy of Eye Diseases
Mesenchymal stem cells (MSCs) possess potent immunomodulatory and regenerative properties. They are, therefore, considered potential new therapeutic...
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Cardiac progenitor cell therapy: mechanisms of action
Heart failure (HF) is an end-stage of many cardiac diseases and one of the main causes of death worldwide. The current management of this disease...
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Emerging Stem Cell Therapy and Tissue Engineering-Based Approaches in Neurodegenerative Diseases
Neurodegenerative diseases are a set of disorders with an increasing prevalence caused by the continuous loss of functional neurons. Treatment of...
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Emerging roles of mesenchymal stem cell therapy in patients with critical limb ischemia
Critical limb ischemia (CLI), the terminal stage of peripheral arterial disease (PAD), is characterized by an extremely high risk of amputation and...
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The role of oxygen tension in cell fate and regenerative medicine: implications of hypoxia/hyperoxia and free radicals
Oxygen pressure plays an integral role in regulating various aspects of cellular biology. Cell metabolism, proliferation, morphology, senescence,...
