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The immune-inflammatory response of oligodendrocytes in a murine model of preterm white matter injury: the role of TLR3 activation
A leading cause of preterm birth is the exposure to systemic inflammation (maternal/fetal infection), which leads to neuroinflammation and white...
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The implications of exosomes in pregnancy: emerging as new diagnostic markers and therapeutics targets
Extracellular vehicles (EVs) are a heterogeneous group of cell and membranous particles originating from different cell compartments. EVs participate...
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Birth size and morphological femininity in adult women
BackgroundWomen’s morphological femininity is perceived to develop under the influence of sex hormones and to serve as a cue of estradiol level,...
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Defining microbial biomarkers for risk of preterm labor
Preterm birth remains the main contributor to early childhood mortality. The vaginal environment, including microbiota composition, might contribute...
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Vaginal Microbiota Is Stable and Mainly Dominated by Lactobacillus at Third Trimester of Pregnancy and Active Childbirth: A Longitudinal Study of Ten Mexican Women
In healthy women at reproductive age, the vaginal microbiota is mainly dominated by Lactobacillus bacteria during pregnancy and non-pregnancy stages....
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Assessing the impact of gestational age of donors on the efficacy of amniotic epithelial cell-derived extracellular vesicles in experimental bronchopulmonary dysplasia
Background and rationaleExtracellular vesicles (EVs) are a potential cell-free regenerative medicine. Human amniotic epithelial cells (hAECs) are a...
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Potential pathogenetic role of a novel ABCC8 missense variant on both transient neonatal diabetes mellitus and fetal growth restriction: a case report
BackgroundThe diagnosis of neonatal diabetes can be problematic in preterm infants with fetal growth restriction (FGR). Growth restricted fetuses may...
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Peptidome analysis of umbilical cord mesenchymal stem cell (hUC-MSC) conditioned medium from preterm and term infants
BackgroundThe therapeutic role of mesenchymal stem cells (MSCs) has been widely confirmed in several animal models of premature infant diseases....
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Human Microbiome and Lifestyle Disorders
The human microbiome builds a multifaceted and dynamic ecosystem with the body that shapes the metabolic as well as immunological behavior of human...
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Reference Range of Plasma Fatty Acids in North Indian Pregnant Population
Reference values for Fatty Acids (FAs) are not well defined in the Indian population. Therefore, it is critical to establish FAs reference range for...
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Microbiome Testing in Female Infertility
Residential commensal microorganisms in the female reproductive tract act as an interface between the host and the outer environment to manifest...
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TRAIL protects the immature lung from hyperoxic injury
The hyperoxia-induced pro-inflammatory response and tissue damage constitute pivotal steps leading to bronchopulmonary dysplasia (BPD) in the...
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Preterm neonatal immunology at the intestinal interface
Fetal and neonatal development represents a critical window for setting a path toward health throughout life. In this review, we focus on intestinal...
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Is the Concentration of Cadmium, Lead, Mercury, and Selenium Related to Preterm Birth?
Environmental pollution and exposure of people to heavy metals cause many bad obstetric outcomes. Our aim is to demonstrate the role of cadmium (Cd),...
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Structural and functional changes in the kidney caused by adverse fetal and neonatal environments
Health and disease risk in the adulthood are known to be affected by the early developmental environment. Kidney diseases are one of these diseases,...
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The orphan nuclear receptor Nr4a1 mediates perinatal neuroinflammation in a murine model of preterm labor
Prematurity is associated with perinatal neuroinflammation and injury. Screening for genetic modulators in an LPS murine model of preterm birth...
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Alvarez waves in pregnancy: a comprehensive review
Alvarez waves are local rhythmic contractions of the myometrium with high frequency and low intensity. They can be detected using internal or...
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Large-scale characterisation of the pregnancy vaginal microbiome and sialidase activity in a low-risk Chinese population
Vaginal microbiota-host interactions are linked to preterm birth (PTB), which continues to be the primary cause of global childhood mortality. Due to...
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Effect of Iodine Nutrition Status on Thyroid Function and Pregnancy Outcomes
Iodine is essential for normal thyroid function, supporting healthy fetal and child development. The relevance between maternal iodine nutrition...
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Health Effects of Aflatoxins in Fetus, Infants, and Children
Aflatoxins are group 1 category carcinogenic compound that are reported in several food commodities well beyond the maximum permissible limits. Early...