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Physical and Chemicals Mutagenesis in Plant Breeding
World agriculture faces the challenge of food security because of the rapid growth of human population, reduced arable land area, plant productivity...
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GOLPH3 promotes endotoxemia-induced liver and kidney injury through Golgi stress-mediated apoptosis and inflammatory response
Sepsis is a serious clinical condition characterized by a systemic inflammatory response, a leading cause of acute liver and kidney injury, and is...
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Genetic perturbation of mitochondrial function reveals functional role for specific mitonuclear genes, metabolites, and pathways that regulate lifespan
Altered mitochondrial function is tightly linked to lifespan regulation, but underlying mechanisms remain unclear. Here, we report the chronological...
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Medicinal Plants and Bioactive Phytochemical Diversity: A Fountainhead of Potential Drugs Against Human Diseases
The diversity of bioactive phytochemicals in plants of medicinal importance is the most precious gift of nature. The floral and phytochemical...
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Practical Considerations in Method Development for Gas Chromatography-Based Metabolomic Profiling
This chapter discusses the fundamentals of gas chromatography (GC) to improve method development for metabolic profiling of complex biological...
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Cell type matters: competence for alkaloid metabolism differs in two seed-derived cell strains of Catharanthus roseus
Since the discovery of the anticancer drugs vinblastine and vincristine, Catharanthus roseus has been intensively studied for biosynthesis of several...
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Current Trends in Biosynthesis, Extraction, Purification, and Refining of Antibiotics
Antibiotics are a class of molecules that resist infections developed by microbes. Antimicrobial resistance is posing a greater threat to combating...
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Automated high-speed 3D imaging of organoid cultures with multi-scale phenotypic quantification
Current imaging approaches limit the ability to perform multi-scale characterization of three-dimensional (3D) organotypic cultures (organoids) in...
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Hydrolytic enzyme screening and carotenoid production evaluation of halophilic archaea isolated from highly heavy metal-enriched solar saltern sediments
This paper aimed to screen the enzymatic activities and evaluate the carotenoid production level of twenty-two halophilic archaea isolated from Sfax...
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Antibody stabilization for thermally accelerated deep immunostaining
Antibodies have diverse applications due to their high reaction specificities but are sensitive to denaturation when a higher working temperature is...
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Multilevel Correlations in the Metabolism of Polyphosphate-Accumulating Organisms
EnhancedEnergy biologicalSystem phosphorus removalEnhanced biological phosphorus removal (EBPREBPR) reliesMetabolism onInorganic polyphosphate...
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Physiological Ecology of Ferns
This is a review of research on the physiological ecology of ferns encompassing aquatic, terrestrial, and epiphytic species. Each of these is...
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Applications of NGS Technology in Forensic DNA Analysis
New technology is being applied to forensic DNA analysis to move samples from collection at the crime scene, to sampling, extraction of DNA, and...
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Nanosponge hydrogel of octadecyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl) propanoate of Alcaligenes faecalis
AbstractOctadecyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl) propanoate (ODHP) was extracted in a previous study from the culture broth of soil isolate Alc...
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ATF3 characterizes aggressive drug-tolerant persister cells in HGSOC
High-grade serous ovarian cancer (HGSOC) represents the most common and lethal subtype of ovarian cancer. Despite initial response to platinum-based...
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Black Pepper
Black pepper (Piper nigrum) probably originated less than 10 MYA (Miocene epoch), coinciding with the intensification of the monsoon climate in...
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Plant-associated bacteria of Syringa vulgaris L. in an urban environment
PurposeBeneficial bacteria contribute significantly to host-plant adaptive capacities. Lilacs are common shrubs of urban areas in a northern climate....
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Cell-Free Expression of Proton-Coupled Folate Transporter in the Presence of Nanodiscs
Proton coupled folate transporter (PCFT) is an integral membrane protein with 12 transmembrane segments localized to the plasma membrane. PCFT is the...
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Continuous Bioprocessing for Upstream Process: Perfusion Process
Perfusion processes are gaining higher interest in the industry for the production of glycoproteins. The intensification that this operation mode can...
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Understanding the Small World: The Microbes
One cannot see the microbes which, in fact, are the leading entity of life on Earth. Other than their widespread occurrence in natural habitats such...