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Major quantitative trait locus qLA3.1 is related to tomato leaf angle by regulating cell length at the petiole base
Key messageqLA3.1, controlling leaf angle in tomato, was fine-mapped to an interval of 4.45 kb on chromosome A03, and one gene encoding auxin...
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Pathogen lifestyle determines host genetic signature of quantitative disease resistance loci in oilseed rape (Brassica napus)
Key messageUsing associative transcriptomics, our study identifies genes conferring resistance to four diverse fungal pathogens in crops, emphasizing...
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Identification and characterization of whole blood gene expression and splicing quantitative trait loci during early to mid-lactation of dairy cattle
BackgroundCharacterization of regulatory variants (e.g., gene expression quantitative trait loci, eQTL; gene splicing QTL, sQTL) is crucial for...
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Exploring relationship between morphological characters with in vitro initiation ability and optimizing in vitro propagation of Vanda orchids
The cultivation of Vanda orchids in Indonesia faces challenges due to their slow growth, leading to a reliance on importing varieties from foreign...
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Map** of quantitative trait loci for the nutritional value of fresh market tomato
The incidence of many diseases, such as cancer, cardiovascular diseases, and diabetes, is associated with malnutrition and an unbalanced daily diet....
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QSAR analysis of five generations of cephalosporins to establish the structural basis of activity against methicillin-resistant and methicillin-sensitive Staphylococcus aureus
Solving the worldwide problem of growing bacterial drug resistance will require a short-run and medium-term strategy. Structure–activity relationship...
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The Human Relationship with Our Ocean Planet
People across the world have diverse economic, sociolegal, institutional, social and cultural relationships with the ocean—both its littoral zones...
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The relationship between spatial patterns of urban land uses and air pollutants in the Tehran metropolis, Iran
ContextUrban expansion has led to land use changes in metropolises, which in turn cause landscape pattern changes and ecological issues in urban...
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A quantitative model of ensemble perception as summed activation in feature space
Ensemble perception is a process by which we summarize complex scenes. Despite the importance of ensemble perception to everyday cognition, there are...
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Qualitative and quantitative evaluation of thylakoid complexes separated by Blue Native PAGE
BackgroundBlue Native polyacrylamide gel electrophoresis (BN PAGE) followed by denaturing PAGE is a widely used, convenient and time efficient method...
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The Effect of Pruning Time on the Quantitative and Qualitative Characteristics of Autumn Sugar Beet
In plants, leaves are the primary source of sunlight, and the production of photosynthetic materials. For this reason, estimating the rate of yield...
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Quantitative trait loci related to growth and wood quality traits in Eucalyptus grandis W. Hill identified through single- and multi-trait genome-wide association studies
The aim of this study was to conduct single- and multi-trait genome wide association studies (GWAS) and identify quantitative trait loci (QTLs) for...
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scDART: integrating unmatched scRNA-seq and scATAC-seq data and learning cross-modality relationship simultaneously
It is a challenging task to integrate scRNA-seq and scATAC-seq data obtained from different batches. Existing methods tend to use a pre-defined gene...
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Major-effect quantitative trait locus qLKR4.1 encodes a phospholipase Dδ protein associated with low-K+ stress tolerance by promoting root length
Key messageqLKR4.1, controlling low K + resistance in tomato, was fine-mapped to an interval of 67.5 kb on chromosome A04, and one gene encoding...
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Synthesis, crystal structure, cholinesterase inhibitory activity, evaluation of insecticidal activities, and computational studies of new phosphonic acids
AbstractIn an attempt to obtain the modified and novel insecticides with low human toxicity, a series of novel mono-, bis-, and tetraphosphonic acid...
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Integration of selective sweeps across the sheep genome: understanding the relationship between production and adaptation traits
BackgroundLivestock populations are under constant selective pressure for higher productivity levels for different selective purposes. This pressure...
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Nuclear compartmentalization as a mechanism of quantitative control of gene expression
Gene regulation requires the dynamic coordination of hundreds of regulatory factors at precise genomic and RNA targets. Although many regulatory...
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Effect of ambient lead on progesterone and pregnancy-associated glycoprotein 1 and their relationship with abortion in Zaraibi goats: a field study
This study aimed to investigate the impact of ambient lead (Pb) exposure on progesterone (P 4 ) and pregnancy-associated glycoprotein 1 (PAG1) and...
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Quantitative proteomics reveals the effect of Yigu decoction (YGD) on protein expression in bone tissue
BackgroundOsteoporosis (OP) is a systemic bone disease characterized by decreased bone mass, destruction of the bone tissue microstructure, increased...
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Applications of Quantitative System Pharmacology Modeling to Model-Informed Drug Development
Significant advances in analytical technologies have dramatically improved our ability to deconvolute disease biology at molecular, cellular, and...