Search
Search Results
-
Identification of a peptide motif that potently inhibits two functionally distinct subunits of Shiga toxin
Shiga toxin (Stx) is a major virulence factor of enterohemorrhagic Escherichia coli , which causes fatal systemic complications. Here, we identified a...
-
Fusion of the SRDX motif to OsPIL11 or OsPIL16 causes rice constitutively photomorphogenic phenotypes in darkness
Dark-grown seedlings develop skotomorphogenesis. Because of the development of rice direct seeding cultivation systems, there is an increasing need...
-
RNA binding motif 47 (RBM47): emerging roles in vertebrate development, RNA editing and cancer
RNA-binding proteins (RBPs) are critical players in the post-transcriptional regulation of gene expression and are associated with each event in RNA...
-
Genome-wide analysis of AP2/ERF transcription factors that regulate fruit development of Chinese prickly ash
BackgroundAP2/ERF is a large family of plant transcription factor proteins that play essential roles in signal transduction, plant growth and...
-
Structural, functional and evolutionary analysis of wheat WRKY45 protein: a combined bioinformatics and MD simulation approach
Bread wheat ( Triticum aestivum L.) is the world's as well as India’s second-most important cereal crop. It is an allohexaploid composed of three...
-
Inhibition of integrin binding to ligand arg-gly-asp motif induces AKT-mediated cellular senescence in hepatic stellate cells
Background & aimsHepatic stellate cells (HSCs) play an essential role in liver fibrogenesis. The induction of cellular senescence has been reported...
-
Genome-wide identification and evolutionary analysis of the NRAMP gene family in the AC genomes of Brassica species
BackgroundBrassica napus , a hybrid resulting from the crossing of Brassica rapa and Brassica oleracea , is one of the most important oil crops....
-
DNA vaccine dual-expressing viral hemorrhagic septicemia virus glycoprotein and C-C motif chemokine ligand 19 induces the expression of immune-related genes in zebrafish (Danio rerio)
Glycoprotein (G protein)-based DNA vaccines are effective in protecting aquaculture fish from rhabdoviruses but the degree of immune response they...
-
Tripartite Motif Containing 3 inhibits the aggressive behaviors of papillary thyroid carcinoma and indicates lower recurrence risk
BackgroundTripartite Motif Containing 3 (TRIM3) has been reported to be downregulated in several malignancies. However, its prognostic significance...
-
Large-scale analysis of the N-terminal regulatory elements of the kinase domain in plant Receptor-like kinase family
BackgroundThe N-terminal regulatory element (NRE) of Receptor-like kinases (RLKs), consisting of the juxtamembrane segment in receptor kinases (RKs)...
-
The SEEL motif and members of the MYB-related REVEILLE transcription factor family are important for the expression of LORELEI in the synergid cells of the Arabidopsis female gametophyte
Synergid cells in the micropylar end of the female gametophyte are required for critical cell–cell signaling interactions between the pollen tube and...
-
Genome-wide identification and evolutionary analysis of WOX gene family in cucurbit crops
The WUSCHEL-related homeobox (WOX) gene family is essential for plant growth and development. However, the identification and evolutionary analysis...
-
Comparative in silico analysis of ascorbate peroxidase protein sequences in different plant species
Ascorbate peroxidase enzymes play a very important role by balancing reactive oxygen species in cells, mainly H 2 O 2 . The present study aims to perform...
-
Identification and promoter analysis of a GA-stimulated transcript 1 gene from Jatropha curcas
Key messageOverexpression of JcGAST1 promotes plant growth but inhibits pistil development. The pyrimidine box and CGTCA motif of the JcGAST1 ...
-
Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif
Apolipoprotein L1 (ApoL1) is a circulating innate immunity protein protecting against trypanosome infection. However, two ApoL1 coding variants are...
-
Genome-wide identification and analysis of superoxide dismutase genes in jute (Corchorus spp.)
Superoxide dismutase (SOD) is an antioxidant enzyme found ubiquitously in all living organisms. It plays a protective role against reactive oxygen...
-
Genome-wide characterization and analysis of the CCT motif family genes in soybean (Glycine max)
Main conclusionSoybean possesses 19 CMF genes which mainly arose from duplication events. Their features and motifs are highly conserved but...
-
TFscope: systematic analysis of the sequence features involved in the binding preferences of transcription factors
Characterizing the binding preferences of transcription factors (TFs) in different cell types and conditions is key to understand how they...
-
RNA interference-mediated knockdown of tripartite motif containing 44 suppresses cervical cancer growth in vitro and in vivo
BackgroundTripartite motif containing 44 (TRIM44) is an atypical member of the TRIM protein family that has been reported to be aberrantly...
-
Functional analysis of recurrent CDC20 promoter variants in human melanoma
Small nucleotide variants in non-coding regions of the genome can alter transcriptional regulation, leading to changes in gene expression which can...
