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A study of extracellular vesicles isolated from blood plasma conducted by low-voltage scanning electron microscopy
Extracellular vesicles secreted by cells represent an almost spherical membrane structures enriched with biological molecules of different types. The...
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Integration of mRNP formation and export
Expression of protein-coding genes in eukaryotes relies on the coordinated action of many sophisticated molecular machineries. Transcription produces...
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Sex-specific recombination maps for individual macrochromosomes in the Japanese quail (Coturnix japonica)
Meiotic recombination in the Japanese quail was directly studied by immunolocalization of mutL homolog 1 (MLH1), a mismatch repair protein of mature...
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In Preparation for New Life II: Gametogenesis – The Development of Egg Cells and Sperm and Their Provision with Heritable Reserves
Frequently in embryo development cells which are not used to construct the soma ‐ the body of the new individual – are put aside and remain in stock... -
Cajal bodies and histone locus bodies: Molecular composition and function
The review provides modern classification of evolutionarily conserved coilin-containing nuclear bodies of somatic and germ cells that is based on the...
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Cytological maps of lampbrush chromosomes of European water frogs (Pelophylax esculentuscomplex) from the Eastern Ukraine
BackgroundHybridogenesis (hemiclonal inheritance) is a kind of clonal reproduction in which hybrids between parental species are reproduced by...
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The Human
Naturally, our main interest is to learn how we ourselves have once developed. How could information of the development of a mouse, or even of a frog... -
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Peculiarities of chromosome organization in meiosis
Meiotic and mitotic chromosomes have a complex of differences. (1) At the early prophase I of meiosis, chromosomes acquire protein axial elements...
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Development of Important Model Species II: Vertebrates
Amphibians represent the archetype of vertebrate development. Figure 5.1 quotes the phylogenetic positions of vertebrates that are often investigated... -
Induction of human lampbrush chromosomes
We previously demonstrated that sperm heads from amphibians ( Xenopus and Rana ) and zebrafish ( Danio ) could form giant lampbrush chromosomes when...
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High-resolution map** and transcriptional activity analysis of chicken centromere sequences on giant lampbrush chromosomes
Exploration into morphofunctional organisation of centromere DNA sequences is important for understanding the mechanisms of kinetochore specification...
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Avian sex, sex chromosomes, and dosage compensation in the age of genomics
Comparisons of the sex chromosome systems in birds and mammals are widening our view and deepening our understanding of vertebrate sex chromosome...
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Association of modified cytosines and the methylated DNA-binding protein MeCP2 with distinctive structural domains of lampbrush chromatin
We have investigated the association of DNA methylation and proteins interpreting methylation state with the distinctive closed and open chromatin...
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Precocious detection on amphibian oocyte lampbrush chromosomes of subtle changes in the cellular localisation of the Ro52 protein induced by in vitro culture
Subterminal lampbrush loops of one of the 12 bivalents of the oocyte karyotype of Pleurodeles waltl (Amphibian, Urodele) underwent prominent...
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Are lampbrush chromosomes unique to meiotic cells?
Lampbrush chromosomes (LBCs) are transcriptionally active chromosomes found in the germinal vesicle (GV) of large oocytes of many vertebrate and...