Search
Search Results
-
Downregulation of the expression of subgenomic chromosome A7 genes promotes plant height in resynthesized allopolyploid Brassica napus
Key messageHomoeolog expression bias and the gene dosage effect induce downregulation of genes on chromosome A7, causing a significant increase in...
-
Random transposon mutagenesis identifies genes essential for transformation in Methanococcus maripaludis
Natural transformation, the process whereby a cell acquires DNA directly from the environment, is an important driver of evolution in microbial...
-
Characterizing the key genes of COVID-19 that regulate tumor immune microenvironment and prognosis in hepatocellular carcinoma
Hepatocellular carcinoma (HCC), a highly heterogeneous malignant tumor associated with a poor prognosis, is a common cause of cancer-related deaths...
-
Genes regulating oxidative-inflammatory response in circulating monocytes and neutrophils in septic syndrome
Despite significant progress in the past decades, sepsis still lacks a specific treatment. Under normal conditions, leucocytes play a critical role...
-
Tissue-wide cell-specific proteogenomic modeling reveals novel candidate risk genes in autism spectrum disorders
Autism spectrum disorders (ASD) are a set of complex neurodevelopmental diseases characterized with repetitive behavioral patterns and communication...
-
Metagenomic profiling of antibiotic resistance genes in Red Sea brine pools
Antibiotic resistance (AR) is an alarming global health concern, causing an annual death rate of more than 35,000 deaths in the US. AR is a natural...
-
Genome-wide identification and expression analysis of the BURP domain-containing genes in Malus domestica
The conserved BURP-containing proteins are specific to plants and play a crucial role in plant growth, development, and response to abiotic stresses....
-
Identifying the genes involved in the egg-carrying ovigerous hair development of the female blue crab Callinectes sapidus: transcriptomic and genomic expression analyses
BackgroundCrustacean female sex hormone (CFSH) controls gradually develo** adult female-specific morphological features essential for mating and...
-
scSNV: accurate dscRNA-seq SNV co-expression analysis using duplicate tag collapsing
Identifying single nucleotide variants has become common practice for droplet-based single-cell RNA-seq experiments; however, presently, a pipeline...
-
Identification and validation of seed dormancy loci and candidate genes and construction of regulatory networks by WGCNA in maize introgression lines
Key messageSeventeen PHS-QTLs and candidate genes were obtained, including eleven major loci, three under multiple environments and two with...
-
Genome-wide identification and expression analysis of TIFY genes under MeJA, cold and PEG-induced drought stress treatment in Dendrobium huoshanense
The TIFY family consists of plant-specific genes that regulates multiple plant functions, including developmental and defense responses. Here, we...
-
CHESS 3: an improved, comprehensive catalog of human genes and transcripts based on large-scale expression data, phylogenetic analysis, and protein structure
CHESS 3 represents an improved human gene catalog based on nearly 10,000 RNA-seq experiments across 54 body sites. It significantly improves current...
-
Ancient homomorphy of molluscan sex chromosomes sustained by reversible sex-biased genes and sex determiner translocation
Contrary to classic theory prediction, sex-chromosome homomorphy is prevalent in the animal kingdom but it is unclear how ancient homomorphic sex...
-
Re-annotation of the Liriodendron chinense genome identifies novel genes and improves genome annotation quality
Liriodendron chinense is a very popular tree used in landsca** because of its beautiful flowers and unique leaf shape. Although the L. chinense ...
-
Genome-wide identification and expression analyses of CYP450 genes in sweet potato (Ipomoea batatas L.)
BackgroundCytochrome P450 monooxygenases (CYP450s) play a crucial role in various biochemical reactions involved in the synthesis of antioxidants,...
-
De Novo Evolution of Genes in Rice
De novo evolution of genes was used as an important approach in the rice breeding program. The identification of the novel genes in the rice genome... -
Genome-wide identification and phylogenetic and expression pattern analyses of EPF/EPFL family genes in the Rye (Secale cereale L.)
Rye ( Secale cereale L.) is one of the major cereal crop species in the Triticeae family and is known to be most tolerant to diverse abiotic stresses,...
-
mRNA levels of tricarboxylic acid cycle genes in Streptomyces coelicolor M145 cultured on glucose
BackgroundStreptomyces strains degrade many complex organic compounds and produce secondary metabolites. In aerobic organisms such as Streptomyces ...
-
Rare variant analyses validate known ALS genes in a multi-ethnic population and identifies ANTXR2 as a candidate in PLS
BackgroundAmyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting over 300,000 people worldwide. It is characterized by the...
-
Genome-wide identification of heavy-metal ATPases genes in Areca catechu: investigating their functionality under heavy metal exposure
Heavy-metal ATPases (HMAs) play a vital role in plants, hel** to transport heavy metal ions across cell membranes.However, insufficient data exists...