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Role of VDR gene polymorphisms and vitamin D levels in normal and overweight patients with PCOS
Polycystic ovary syndrome (PCOS) is one of the most common endocrine diseases in women. In recent years, the effects of vitamin D receptor (VDR) gene...
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Antipsychotics increase steroidogenic enzyme gene expression in the rat brainstem
BackgroundNeurosteroids are involved in several important brain functions and have recently been considered novel players in the mechanic actions of...
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Phytoestrogens Responsible for Altered Pubertal Timing in Females: A Matter of Concern
Endocrine disrupting chemicals are xenobiotic substances which interferes with the body’s conventional endocrine pathways hindering its normal...
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Influence of Testosterone on Different Aspects of Bird Behavior and Physiology
Abstract —More than 50 years works on the role of testosterone in passerine birds are analyzed. The testosterone influence on different aspects of...
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Impacts of Acrylamide on testis and spermatozoa
Acrylamide (ACR) is an industrial chemical used to produce polyacrylamide, a synthetic polymer with a wide range of applications. Depending on the...
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Production of 11α-Hydroxysteroid Derivatives by Corynebacterium glutamicum Expressing the Rhizopus oryzae Hydroxylating System
Hydroxylation of steroids has acquired special relevance for the pharmaceutical industry. Particularly, the 11α-hydroxylation of steroids is a...
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The Effects of Chronic Lead Exposure on Testicular Development of Japanese Quail (Coturnix japonica): Histopathological Damages, Oxidative Stress, Steroidogenesis Disturbance, and Hypothalamus-Pituitary-Testis Axis Disruption
Lead (Pb) becomes a global public health concern for its high toxicology. Birds are sensitive to environmental pollution and Pb contamination exerts...
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Transplantation of human umbilical cord mesenchymal stem cells to treat premature ovarian failure
As one of the problems and diseases for women before 40 years, premature ovarian failure (POF) could be characterized by amenorrhea, low estrogen...
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The role of zinc in follicular development
Follicles consist of specialized somatic cells that encase a single oocyte. Follicle development is a process regulated by a variety of endocrine,...
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Weightlessness leads to an increase granulosa cells in the growing follicle
The participation of women in space programs of increasing flight duration requires research of their reproductive system from the perspective of...
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Sex differences in colorectal cancer: with a focus on sex hormone–gut microbiome axis
Sexual dimorphism has been observed in the incidence and prognosis of colorectal cancer (CRC), with men generally exhibiting a slightly higher...
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Insights on the NF-κB system in polycystic ovary syndrome, attractive therapeutic targets
The nuclear factor κappa B (NF-κB) signaling plays a well-known function in inflammation and regulates a wide variety of biological processes....
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Exploring the potential of Aspergillus wentii: secondary metabolites and biological properties
Fungi are of considerable importance due to their capacity to biosynthesize various secondary metabolites with bioactive properties that draw high...
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Evaluation of the psychophysiological effects of the Cupressaceae family wood odor
The wood of the Cupressaceae conifer family is widely used for many purposes, such as the structural and interior elements of buildings. Several...
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Biomarkers of oxidative stress, diet and exercise distinguish soldiers selected and non-selected for special forces training
IntroductionThe metabolomic profiles of Soldiers entering the U.S. Special Forces Assessment and Selection course (SFAS) have not been evaluated.
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Elevated luteinizing hormone receptor signaling or selenium treatment leads to comparable changes in adrenal cortex histology and androgen-AR/ZIP9 signaling
The importance and regulation of adrenal androgen production and signaling are not completely understood and are scarcely studied. In addition, there...
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Metagenomic and metabolomic remodeling in nonagenarians and centenarians and its association with genetic and socioeconomic factors
A better understanding of the biological and environmental variables that contribute to exceptional longevity has the potential to inform the...
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Reproduction
Eels do not mature under captive conditions. It is not uncommon for fish to begin and complete their final maturation under closed aquaculture...
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Biosynthesis of eriodictyol in citrus waster by endowing P450BM3 activity of naringenin hydroxylation
AbstractThe flavonoid naringenin is abundantly present in pomelo peels, and the unprocessed naringenin in wastes is not friendly for the environment...
