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A Marine Group A isolate relies on other growing bacteria for cell wall formation
Most of Earth’s prokaryotes live under energy limitation, yet the full breadth of strategies that enable survival under such conditions remain poorly...
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DNA satellite and chromatin organization at mouse centromeres and pericentromeres
BackgroundCentromeres are essential for faithful chromosome segregation during mitosis and meiosis. However, the organization of satellite DNA and...
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A Green one-pot three component synthesis of thiazolidine-2,4-dione based bisspirooxindolo-pyrrolidines with [Bmim]BF4: their in vitro and in silico anti-TB studies
A simple and effective three-component one-pot green methodology was employed for the synthesis of a new thiazolidine-2,4-dione based...
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Phytosterol conversion into C9 non-hydroxylated derivatives through gene regulation in Mycobacterium fortuitum
AbstractAndrost-4-ene-3,17-dione (AD) and 22-hydroxy-23,24-bisnorchol-4-ene-3-one (4-HBC) are important drug intermediates that can be biosynthesized...
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Analysis of FctB3 crystal structure and insight into its structural stabilization and pilin linkage mechanisms
Streptococcus pyogenes harboring an FCT type 3 genomic region display pili composed of three types of pilins. In this study, the structure of the...
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Gymnodinialimonas ceratoperidinii gen. nov., sp. nov., isolated from rare marine dinoflagellate Ceratoperidinium margalefii
A bacterial strain, designated J12C1-MA-4 T , was isolated from liquid culture of the dinoflagellate Ceratoperidinium margalefii . The bacterium was...
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Capturing the microbial dark matter in desert soils using culturomics-based metagenomics and high-resolution analysis
Deserts occupy one-third of the Earth’s terrestrial surface and represent a potentially significant reservoir of microbial biodiversity, yet the...
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Widespread Bradyrhizobium distribution of diverse Type III effectors that trigger legume nodulation in the absence of Nod factor
The establishment of the rhizobium-legume symbiosis is generally based on plant perception of Nod factors (NFs) synthesized by the bacteria. However,...
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Production of 21-hydroxy-20-methyl-pregna-1,4-dien-3-one by modifying multiple genes in Mycolicibacterium
AbstractC22 steroid drug intermediates are suitable for corticosteroids synthesis, and the production of C22 steroids is unsatisfactory due to the...
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Facemask acne attenuation through modulation of indirect microbiome interactions
During the COVID-19 pandemic, facemasks played a pivotal role in preventing person-person droplet transmission of viral particles. However, prolonged...
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Phenotypic and molecular characterization of clinically isolated antibiotics-resistant S. aureus (MRSA), E. coli (ESBL) and Acinetobacter 1379 bacterial strains
Antibiotic-resistant bacteria causing nosocomial infections pose a significant global health concern. This study focused on examining the lipid...
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Probiotic potential of Tetragenococcus halophilus EFEL7002 isolated from Korean soy Meju
BackgroundProbiotic starters can improve the flavor profile, texture, and health-promoting properties of fermented foods. Tetragenococcus halophilus ...
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Genetic mechanisms underlying increased microalgal thermotolerance, maximal growth rate, and yield on light following adaptive laboratory evolution
BackgroundAdaptive laboratory evolution (ALE) is a powerful method for strain optimization towards abiotic stress factors and for identifying...
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Screening Microbial Interactions During Inulin Utilization Reveals Strong Competition and Proteomic Changes in Lacticaseibacillus paracasei M38
Competition for resources is a common microbial interaction in the gut microbiome. Inulin is a well-studied prebiotic dietary fiber that profoundly...
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Cryptococcus neoformans Transcriptome Analysis to Identify Differentially Expressed Genes Using the STAR Pipeline in CyVerse Discovery Environment
RNA sequencing is a next-generation sequencing approach that may be used to investigate many aspects of gene expression changes between cells....
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Molecular Detection and Characterization of ‘Candidatus Phytoplasma mali’ Associated With Phyllody on Narcissus tazetta in Türkiye
In the winter of 2019, typical phyllody, flower sterility, and stunting symptoms were observed on daffodil plants ( Narcissus tazetta ) in the Mersin...
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Genetic regulation and fermentation strategy for squalene production in Schizochytrium sp.
AbstractSqualene, as an important terpenoid, is extensively used in the medicine and health care fields owing to its functions of anti-oxidation,...
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Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores
Poxviruses are among the largest double-stranded DNA viruses, with members such as variola virus, monkeypox virus and the vaccination strain vaccinia...
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Halomonas salipaludis sp. nov., isolated from a saline-alkali wetland soil
Strain WRN001 T , a Gram-staining-negative, strictly aerobic, non-motile bacterium was isolated from the natural saline-alkali wetland soil of Binhai...
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Bacterial c-di-GMP signaling gene affects mussel larval metamorphosis through outer membrane vesicles and lipopolysaccharides
Biofilms serve as crucial cues for settlement and metamorphosis in marine invertebrates. Within bacterial systems, c-di-GMP functions as a pivotal...
