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Single nucleotide polymorphisms of growth hormone gene in cattle and their association with growth traits: a systematic review
Growth traits in livestock animals are quantitative parameters, which are often controlled by many genes including growth hormone (GH) gene. However,...
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Angiotensin-converting enzyme gene (ACE) polymorphisms are associated with dysregulation of biochemical parameters in hypertensive patients
IntroductionThe genetic component, including genes and their variants, plays a significant role in the pathophysiology of arterial hypertension (AH)....
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Association of ACE gene polymorphisms with in-stent restenosis by stent type (biomime, supraflex, xience)
IntroductionAngiotensin Converting Enzyme or ACE is an exo-peptidase that causes the conversion of angiotensin I to angiotensin II, vasoconstriction,...
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Lactoferrin gene polymorphisms associated with clinical mastitis in Honduran Holstein inheritance cows
BackgroundLactoferrin (LTF) is an iron-binding glycoprotein found in milk and other exocrine secretion with antibacterial activity proposed as an...
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The interplay between HLA-B and NLRP3 polymorphisms may be associated with the genetic susceptibility of gout
BackgroundHLA and NLRP3 play an important role in the development of various autoimmune and autoinflammatory diseases. Gout is an autoinflammatory...
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Association of PFN1 Gene Polymorphisms with Bone Mineral Density, Bone Turnover Markers, and Osteoporotic Fractures in Chinese Population
Recent studies have discovered an association between the PFN1 gene and Paget’s disease. However, it is currently unknown whether the PFN1 gene is...
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Genetic susceptibility of vitamin D receptor gene polymorphisms on autosomal recessive primary microcephaly patients in Pakistani population: a case-control and in-silico study
BackgroundAutosomal recessive primary microcephaly (MCPH) is a rare genetic disorder that leads to reduced cerebral cortex caused by a mutation in...
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Two amino-acid polymorphisms in PBP4 generate penicillin tolerance in group B streptococcus
Group B streptococci (GBS) bacteria are the leading cause of neonatal infections in the US. GBS strains may exhibit prolonged resilience to clinical...
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No association of prion protein gene (PRNP) polymorphisms with susceptibility to the pandemic 2009 swine flu
BackgroundThe pandemic 2009 swine flu is a highly infectious respiratory disorder caused by H1N1 influenza A viruses. A recent study reported that...
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Transposable element polymorphisms improve prediction of complex agronomic traits in rice
Key messageTransposon insertion polymorphisms can improve prediction of complex agronomic traits in rice compared to using SNPs only, especially when...
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Association of xenobiotic-metabolizing genes polymorphisms with cervical cancer risk in the Tunisian population
BackgroundHost genetic characteristics and environmental factors interactions may play a crucial role in cervical carcinogenesis. We investigated the...
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Associations of long non-coding RNAs HOTAIR, LINC00951, POLR2E and HULC polymorphisms with the risk of esophageal and esophagogastric junction cancer in a western population: a case-control study
BackgroundThe incidence of single-nucleotide-polymorphisms with malignant potential in esophageal cancer tissues has only been sparsely investigated...
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Association of IGF1R polymorphisms with kidney function-related traits
BackgroundUnimpaired kidney function is important for maintaining a healthy state of homeostasis in the body. A genome-wide association study (GWAS)...
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Sex-related differences in single nucleotide polymorphisms associated with dyslipidemia in a Korean population
BackgroundThe prevalence of dyslipidemia has increased steadily in Korea, and the incidence of dyslipidemia differs by sex. In this study, we...
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Effects of CYP24A1 polymorphisms on premature ejaculation: a case–control study
Premature ejaculation (PE) is a common male sexual dysfunction disorder, and is considered to have the genetic predisposition. However, the internal...
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Association investigations between ACE1 and ACE2 polymorphisms and severity of COVID-19 disease
Due to the unique affinity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to the angiotensin-converting enzyme 2 (ACE2) receptor...
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Association of gene polymorphisms with body weight changes in prediabetic patients
BackgroundRecent research has demonstrated that Type 2 Diabetes (T2D) risk is influenced by a number of common polymorphisms, including MC4R ...
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Forkhead box P3 gene polymorphisms predispose to type 2 diabetes and diabetic nephropathy in the Han Chinese populations: a genetic-association and gender-based evaluation study
BackgroundFunctional mutations or polymorphisms affecting forkhead box P3 ( FOXP3) can lead to their abnormal FOXP3 gene expression and/or defective...
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A review on the genetic polymorphisms and susceptibility of cancer patients in Bangladesh
Cancer is one of the major health burdens worldwide, and genetic polymorphisms in individuals are closely associated with cancer susceptibility. Like...
