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Metabolic shift toward ketosis in asocial cavefish increases social-like affinity
BackgroundSocial affinity and collective behavior are nearly ubiquitous in the animal kingdom, but many lineages feature evolutionarily asocial...
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Altered metabolome and microbiome features provide clues in understanding irritable bowel syndrome and depression comorbidity
Irritable bowel syndrome (IBS) is one of the functional gastrointestinal disorders characterized by chronic and/or recurrent symptoms of abdominal...
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Contribution of environmental, genetic and epigenetic factors to obesity-related metabolic syndrome
Non-communicable lifestyle diseases and related mortality are increasing rapidly over the last few decades. Obesity is one of the major concerning...
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Acute metabolic alterations in the hippocampus are associated with decreased acetylation after blast induced TBI
IntroductionBlast induced Traumatic brain injury (BI-TBI) is common among military personnels as well as war affected civilians. In the war zone,...
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Metabolomic signatures associated with depression and predictors of antidepressant response in humans: A CAN-BIND-1 report
One of the biggest challenges in treating depression is the heterogeneous and qualitative nature of its clinical presentations. This highlights the...
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Genomic patterns of homozygosity and inbreeding depression in Murciano-Granadina goats
BackgroundInbreeding depression can adversely affect traits related to fitness, reproduction and productive performance. Although current research...
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Effects of lactoferrin on intestinal flora of metabolic disorder mice
To study the mechanism of lactoferrin (LF) regulating metabolic disorders in nutritionally obese mice through intestinal microflora. Twenty-one male...
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Metabolic responses of plasma to extreme environments in overwintering Tibetan frogs Nanorana parkeri: a metabolome integrated analysis
Many animals lower their metabolic rate in response to low temperatures and scarcity of food in the winter in phenomena called hibernation or...
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The circadian night depression of photosynthesis analyzed in a herb, Pulmonaria vallarsae. Day/night quantitative relationships
Although many photosynthesis related processes are known to be controlled by the circadian system, consequent changes in photosynthetic activities...
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Recent advances in metabolic regulation and bioengineering of gibberellic acid biosynthesis in Fusarium fujikuroi
The plant growth hormone gibberellic acid (GA 3 ), as one of the representative secondary metabolites, is widely used in agriculture, horticulture and...
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Features of the Influence of the Autonomic Nervous System on the Regulatory and Metabolic Parameters of Lymphocytes in Healthy Children and Children with Special Health Needs
AbstractThe aim of the study was to analyze the content of biogenic monoamines (catecholamins and serotonin) and metabolic parameters (activities of...
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The Effect of Selenium Supplementation on Clinical Outcomes, Metabolic Profiles, and Pulsatility Index of the Uterine Artery in High-Risk Mothers in Terms of Preeclampsia Screening with Quadruple Test: a Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Data on the effects of selenium (Se) supplementation on clinical outcomes, metabolic profiles, and pulsatility index (PI) in high-risk mothers in...
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Identification of the molecular mechanism of insulin-like growth factor-1 (IGF-1): a promising therapeutic target for neurodegenerative diseases associated with metabolic syndrome
Neurodegenerative disorders are accompanied by neuronal degeneration and glial dysfunction, resulting in cognitive, psychomotor, and behavioral...
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The DNA methylation status of the serotonin metabolic pathway associated with reproductive inactivation induced by long-light exposure in Magang geese
BackgroundDomestic geese are seasonal breeders and have the lowest reproductive capacity among all poultry species. Magang geese is a topical...
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Natural variability in seawater temperature compromises the metabolic performance of a reef-forming cold-water coral with implications for vulnerability to ongoing global change
Seawater temperature is one of the main variables that determines cold-water coral distribution worldwide. As part of an initiative to explore new...
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Upregulation of S100A8 in peripheral blood mononuclear cells from patients with depression treated with SSRIs: a pilot study
BackgroundMajor depressive disorder (MDD) affects more than 350 million people worldwide, and there is currently no laboratory test to diagnose it....
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Oral d-ribose causes depressive-like behavior by altering glycerophospholipid metabolism via the gut-brain axis
Our previous work has shown that d -ribose (RIB)-induced depressive-like behaviors in mice. However, the relationship between variations in RIB levels...
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Trans cohort metabolic reprogramming towards glutaminolysis in long-term successfully treated HIV-infection
Despite successful combination antiretroviral therapy (cART), persistent low-grade immune activation together with inflammation and toxic...
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Metabolic Mechanism of Glycyrrhiza uralensis Fresh Root under Drought Stress Simulated with Polyethylene Glycol-6000
AbstractLicorice ( Glycyrrhiza uralensis Fisch.) is the most widely used botanical medicine in China, an annual demand of 60 thousand tons leads to...
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Reserpine-Induced Depression and Other Neurotoxicity: A Monoaminergic Hypothesis
Depression is a disease that many suffer at some point in their lifetime. Depression can present as an array of symptoms spanning from tiredness to...