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Complete genome sequence, phenotypic correlation and pangenome analysis of uropathogenic Klebsiella spp
Urinary tract infections (UTI) by antibiotic resistant and virulent K. pneumoniae are a growing concern. Understanding the genome and validating the...
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rol Genes of Agrobacteria: Possible Biological Functions
AbstractAs a result of agrobacterium-mediated transformation, the rolA, rolB, rolC , and rolD genes of Agrobacterium rhizogenes are integrated into...
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The polyglutamine protein ATXN2: from its molecular functions to its involvement in disease
A CAG repeat sequence in the ATXN2 gene encodes a polyglutamine (polyQ) tract within the ataxin-2 (ATXN2) protein, showcasing a complex landscape of...
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The dopamine transporter antagonist vanoxerine inhibits G9a and suppresses cancer stem cell functions in colon tumors
Cancer stem cells (CSCs), functionally characterized by self-renewal and tumor-initiating activity, contribute to decreased tumor immunogenicity,...
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Epigenetic modulation of myeloid cell functions in HIV and SARS-CoV-2 infection
Myeloid cells play a vital role in innate immune responses as they recognize and phagocytose pathogens like viruses, present antigens, produce...
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On the stability of canonical correlation analysis and partial least squares with application to brain-behavior associations
Associations between datasets can be discovered through multivariate methods like Canonical Correlation Analysis (CCA) or Partial Least Squares...
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Mechanisms and functions of RNA-guided RNA modification
RNA-guided 2’-O-methylations and pseudouridylations occur in several different types of RNAs and in a wide range of organisms. Hundreds of the RNAs...
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Advances in research of biological functions of Isthmin-1
Isthmin-1 (ISM1) was initially thought to be a brain secretory factor, but with the development of technical means of research and the refinement of...
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Distance correlation application to gene co-expression network analysis
BackgroundTo construct gene co-expression networks, it is necessary to evaluate the correlation between different gene expression profiles. However,...
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Probing the RNA Structure-Dependent RNA Regulations and Functions
RNAs form complex structures in vivo to perform diverse functions. These RNA structures dynamically change in response to internal cellular...
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Exploring the Correlation Between Varied Serum Iodine Nutritional Levels and Anti-Thyroglobulin Antibodies
Iodine deficiency results in elevated thyroglobulin (Tg) concentrations, with high iodine Tg being more immunogenic than low iodine Tg. The study...
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Low and Moderate Rice-Sodic Soils Affect Bacterial Diversity and Their Functions
Sodicity is a significant abiotic stress that impairs plant growth and crop production. Understanding their properties is critical to establishing...
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Cyanobacterial Genomes from a Brackish Coastal Lagoon Reveal Potential for Novel Biogeochemical Functions and Their Evolution
Cyanobacteria are recognised for their pivotal roles in aquatic ecosystems, serving as primary producers and major agents in diazotrophic processes....
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Metagenomic sequencing reveals altered gut microbial compositions and gene functions in patients with non-segmental vitiligo
BackgroundVitiligo has been correlated with an abnormal gut microbiota. We aimed to systematically identify characteristics of the gut microbial...
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Being ahead of the game—the association between executive functions and football performance in high-level football players
The current study examined the association between executive functions and the performance of high-level football players. Participants of the study (
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Comprehensive analysis of TCGA data reveals correlation between DNA methylation and alternative splicing
The effect of DNA methylation on the regulation of gene expression has been extensively discussed in the literature. However, the potential...
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Measurement of Protein and Nucleic Acid Diffusion Coefficients Within Biomolecular Condensates Using In-Droplet Fluorescence Correlation Spectroscopy
Liquid-liquid phase separation of protein and RNA complexes into biomolecular condensates has emerged as a ubiquitous phenomenon in living systems....
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Non-canonical functions of spliceosome components in cancer progression
Dysregulation of pre-mRNA splicing is a common hallmark of cancer cells and it is associated with altered expression, localization, and mutations of...
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Daily singing of adult songbirds functions to maintain song performance independently of auditory feedback and age
Many songbirds learn to produce songs through vocal practice in early life and continue to sing daily throughout their lifetime. While it is...
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Emerging functions within the enzyme families of plant alkaloid biosynthesis
The alkaloids are a major class of nitrogen-containing plant specialized metabolites that function as both toxic defense compounds and useful...
