Search
Search Results
-
Combined analysis of mRNA and miRNA transcriptomes reveals the regulatory mechanism of Xanthomonas arboricola pv pruni resistance in Prunus persica
BackgroundPeach bacterial shot hole, caused by Xanthomonas arboricola pv pruni (Xap), is a global bacterial disease that poses a threat to the yield...
-
Ultrasound-Induced Enrichment of Ultra-Trace miRNA Biosensing in Nanoliter Samples
The rapid and accurate analysis of micro-samples is a crucial foundation for precision medicine, particularly for early screening and monitoring of...
-
Synchronous Mutual Learning Network and Asynchronous Multi-Scale Embedding Network for miRNA-Disease Association Prediction
MicroRNA (miRNA) serves as a pivotal regulator of numerous cellular processes, and the identification of miRNA-disease associations (MDAs) is crucial...
-
Integrative analysis of genomic and epigenomic regulation reveals miRNA mediated tumor heterogeneity and immune evasion in lower grade glioma
The expression dysregulation of microRNAs (miRNA) has been widely reported during cancer development, however, the underling mechanism remains...
-
Circulating miRNA-373 and Vascular Endothelial Growth Factor as Potential Biomarkers for Early Detection of Breast Cancer
Breast cancer is the leading cause of cancer-related mortality among women worldwide. MicroRNAs (miRNAs), short non-coding RNAs, have been implicated...
-
Exploring the dynamic adaptive responses of Epimedium pubescens to phosphorus deficiency by Integrated transcriptome and miRNA analysis
Phosphorus, a crucial macronutrient essential for plant growth and development. Due to widespread phosphorus deficiency in soils, phosphorus...
-
GKLOMLI: a link prediction model for inferring miRNA–lncRNA interactions by using Gaussian kernel-based method on network profile and linear optimization algorithm
BackgroundThe limited knowledge of miRNA–lncRNA interactions is considered as an obstruction of revealing the regulatory mechanism. Accumulating...
-
Predicting abiotic stress-responsive miRNA in plants based on multi-source features fusion and graph neural network
BackgroundMore and more studies show that miRNA plays a crucial role in plants' response to different abiotic stresses. However, traditional...
-
The accumulation of modular serine protease mediated by a novel circRNA sponging miRNA increases Aedes aegypti immunity to fungus
BackgroundMosquitoes transmit many infectious diseases that affect human health. The fungus Beauveria bassiana is a biological pesticide that is...
-
MiRNA miR-375 as a Multifunctional Regulator of the Cardiovascular System
AbstractMicroRNA (miRNA) miR-375 acts as a multifunctional regulator of the activity of many physiological and pathological cellular processes by...
-
MiRNA fine tuning for crop improvement: using advance computational models and biotechnological tools
MiRNAs modulate target genes expression at post-transcriptional levels, by reducing spatial abundance of mRNAs. MiRNAs regulats plant metabolism, and...
-
Erythrocyte miRNA-92a-3p interactions with PfEMP1 as determinants of clinical malaria
Based on the recently added high throughput analysis data on small noncoding RNAs in modulating disease pathophysiology of malaria, we performed an...
-
The role of miRNA and lncRNA in heterotopic ossification pathogenesis
Heterotopic ossification (HO) is the formation of bone in non-osseous tissues, such as skeletal muscles. The HO could have a genetic or a non-genetic...
-
Recent developments in miRNA based recombinant protein expression in CHO
It is widely accepted that the growing demand for recombinant therapeutic proteins has led to the expansion of the biopharmaceutical industry and the...
-
Comparative analysis of miRNA expression profiles in flowering and non-flowering tissue of Crocus sativus L
Crocus sativus is a valuable plant due to the presence of apocarotenoids in its stigma. Considerable work has been done in the past to understand the...
-
CircRNA–miRNA interactions in atherogenesis
Atherosclerosis is the major cause of coronary artery disease (CAD) which includes unstable angina, myocardial infarction, and heart failure. The...
-
miRNA-mRNA analysis of sheep adrenal glands reveals the network regulating reproduction
BackgroundThe adrenal gland participates in the process of sheep reproduction. MicroRNAs (miRNAs), endogenous small noncoding RNAs, regulate gene...
-
Binding sites of miRNA on the overexpressed genes of oral cancer using 7mer-seed match
The microRNAs having a length of ~ 19–22 nucleotides are the small, non-coding RNAs. The evolution of microRNAs in many disorders may hold the key to...
-
A repertoire of intronic lariat RNAs reveals tissue-specific regulation and target mimicry potential in plants
Lariat RNA is concomitantly produced by excised intron during RNA splicing, which is usually debranched by DBR1, an RNA debranching enzyme. However,...
-
Understanding the evolution of miRNA biogenesis machinery in plants with special focus on rice
miRNA biogenesis process is an intricate and complex event consisting of many proteins working in a highly coordinated fashion. Most of these...
