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Pre-clinical evaluation of the efficacy and safety of human induced pluripotent stem cell-derived cardiomyocyte patch
BackgroundCell- or tissue-based regenerative therapy is an attractive approach to treat heart failure. A tissue patch that can safely and effectively...
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Plecotus macrobullaris sarmaticus subsp. nov. (Vespertilionidae, Chiroptera) from the Early Pleistocene of Crimea
AbstractThe extinct mountain long-eared bat Plecotus macrobullaris sarmaticus subsp. nov. is described on the base of jaw remains from the Lower...
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Exploring chronic and transient tumor hypoxia for predicting the efficacy of hypoxia-activated pro-drugs
Hypoxia, a low level of oxygen in the tissue, arises due to an imbalance between the vascular oxygen supply and oxygen demand by the surrounding...
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Feeding-Related Skull Structures of Climbing Perch Anabas testudineus (Anabantidae)
AbstractThe feeding-related skull structures are described and occluding elements of the upper and lower regions of the buccopharyngeal cavity are...
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Cysteine-rich with EGF-like domains 2 (CRELD2) is an endoplasmic reticulum stress-inducible angiogenic growth factor promoting ischemic heart repair
Tissue repair after myocardial infarction (MI) is guided by autocrine and paracrine-acting proteins. Deciphering these signals and their upstream...
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New materials of Pliorhinus ringstroemi from the Linxia Basin (Late Miocene, eastern Asia) and their taxonomical and evolutionary implications
A large collection of dicerorhine rhinoceros remains, here identified as Pliorhinus ringstroemi , were studied from the Late Miocene deposits of the...
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The hindlimb myology of the South American eagle Geranoaetus melanoleucus (Accipitridae, Aves)
Geranoaetus melanoleucus is a widely distributed accipitrid across South America. Like other accipitrids, it employs powerful hindlimb muscles to...
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First record of Posnanskytherium (Notoungulata, Toxodontidae) in the late Neogene of eastern Puna, Argentina
Records of the toxodontid Posnanskytherium were only known from the Pliocene levels of the Bolivian Altiplano and southern Peru. Posnanskytherium...
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The Great Crested Newt, Triturus cristatus (Laurenti 1768) (Caudata, Salamandridae), near the Eastern Limit of Its Distribution Area in the Middle Urals
AbstractUpdated information on the distribution and studied populations of T. cristatus on the eastern macro-slope of the Urals (Middle and Southern...
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Incidence of eriophyid mites (Acariformes: Eriophyidae) and predatory mites (Parasitiformes: Phytoseiidae) in Florida citrus orchards under three different pest management programs
The abundance and diversity of eriophyid and phytoseiid mites in south and central Florida were assessed in six citrus orchards under three different...
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Revealing the hidden marine dagaa cross-border trade in mainland Tanzania
Informal cross-border fish trade (ICBFT) is becoming predominant in many African nations and unfortunately there is little information on its...
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An invasive zone in human liver cancer identified by Stereo-seq promotes hepatocyte–tumor cell crosstalk, local immunosuppression and tumor progression
Dissecting and understanding the cancer ecosystem, especially that around the tumor margins, which have strong implications for tumor cell...
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Variation in macrobenthic community of vegetated and unvegetated habitats in a macrotidal estuary of northern Brazilian Amazon coast
Comparisons among vegetated and unvegetated intertidal habitats have led to the paradigm that benthic fauna are more abundant and diverse in the...
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Topography landmarks of the infraorbital, mandibular and mentual foramens of Saimiri collinsi (Osgood, 1916) for anesthetic access and blocks
Due to events related to the urbanization process, specimens of Saimiri collinsi are often referred to veterinarians specializing in the treatment of...
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High-throughput detection of T-DNA insertion sites for multiple transgenes in complex genomes
BackgroundGenetic engineering of crop plants has been successful in transferring traits into elite lines beyond what can be achieved with breeding...
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Macrophage neogenin deficiency exacerbates myocardial remodeling and inflammation after acute myocardial infarction through JAK1-STAT1 signaling
Immune response plays a crucial role in post-myocardial infarction (MI) myocardial remodeling. Neogenin (Neo1), a multifunctional transmembrane...
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Coexistence field trials between MON810 and conventional maize in Mallorca as a basis for a regional regulatory proposal based on scientific evidence in the times of genome editing
This paper reports the first coexistence field trials between transgenic and conventional maize carried out under Mediterranean island conditions....
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E3 Ubiquitin Ligase ASB14 Inhibits Cardiomyocyte Proliferation by Regulating MAPRE2 Ubiquitination
The ubiquitin proteasome system is a highly specific and selective protein regulatory system that plays an essential role in the regulation of the...
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Linkage between forest cover and trade in forest products: an empirical evidence from BRICS and EU nations
The present research aims at analyzing the determinants of trade in forest products across BRICS and EU nations by using forest cover as one of the...
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Single-cell expression profile of Drosophila ovarian follicle stem cells illuminates spatial differentiation in the germarium
BackgroundHow stem cell populations are organized and regulated within adult tissues is important for understanding cancer origins and for develo**...
