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DNA methylation may affect beef tenderness through signal transduction in Bos indicus
BackgroundBeef tenderness is a complex trait of economic importance for the beef industry. Understanding the epigenetic mechanisms underlying this...
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Reactive Oxygen Species: Role in Senescence and Signal Transduction
Reactive oxygen species (ROS) play a dual role in the plant kingdom. Previously, they were recognized as an inevitable toxic byproduct of cellular...
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A mitochondrial membrane-bridging machinery mediates signal transduction of intramitochondrial oxidation
Mitochondria are the main site for generating reactive oxygen species, which are key players in diverse biological processes. However, the molecular...
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A Practical Guide for the Efficient Formulation and Calibration of Large, Energy- and Rule-Based Models of Cellular Signal Transduction
Aberrant signal transduction leads to complex diseases such as cancer. To rationally design treatment strategies with small molecule inhibitors,...
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The involvement of gaseous signaling molecules in plant MAPK cascades: function and signal transduction
Main conclusionThis review describes the interaction of gaseous signaling molecules and MAPK cascade components, which further reveals the specific...
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Research progress on Toll-like receptor signal transduction and its roles in antimicrobial immune responses
When microorganisms invade a host, the innate immune system first recognizes the pathogen-associated molecular patterns of these microorganisms...
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Transcriptomics analysis reveals the signal transduction mechanism of brassinolides in tea leaves and its regulation on the growth and development of Camellia sinensis
BackgroundBrassinosteroids (BRs) are a type of sterol plant hormone that play an important role in various biochemical and physiological reactions...
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Methionine sulfoxide and the methionine sulfoxide reductase system as modulators of signal transduction pathways: a review
Methionine oxidation and reduction is a common phenomenon occurring in biological systems under both physiological and oxidative-stress conditions....
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Cell Cycle Signal Transduction and Proteolysis in Caulobacter
Caulobacter crescentus is an extremely informative model system for studies of the bacterial cell division cycle. Caulobacter resembles eukaryotes...
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Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression
The development of transgenic mouse models that express genes of interest in specific cell types has transformed our understanding of basic biology...
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Stress Proteins and Signal Transduction in Cyanobacteria
Stress-induced proteomics unveils various adaptive mechanisms evolved by cyanobacteria to combat different environmental stresses. Acclimation...
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Effects of increasing temperature and aestivation on biogenic amines, signal transduction pathways and metabolic enzyme activities in the sea cucumber (Apostichopus japonicus)
Marine invertebrates are facing increasing pressure from climate change, such as increasing temperature. Sea cucumber ( Apostichopus japonicus ) is an...
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An effector–reporter system to study cellular signal transduction in strawberry fruit (Fragaria ananassa)
An effector–reporter system is a powerful tool used to study cellular signal transduction, but this technique has been traditionally used in...
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Comparative transcriptome analysis reveals the function of SlPRE2 in multiple phytohormones biosynthesis, signal transduction and stomatal development in tomato
Key messageTranscriptomic, physiological, and qRT-PCR analysis revealed the potential mechanism by which SlPRE2 regulates plant growth and stomatal...
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Imaging of the Ciliary Cholesterol Underlying the Sonic Hedgehog Signal Transduction
Primary cilia are antenna-like structures that develop on the surface of quiescent G0-phase cells and receive extracellular signals including sonic...
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The Stomatal Openings Occurred from Blue Light Photoreceptors Mediated Signal Transduction Pathway May be Enhanced by a Blue Light Stimulated Photosynthesis
AbstractStomata open by transporting of osmotic materials to the guard cell vacuole. In the mechanisms of stomatal opening, the transports of osmotic...
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Identifying patient-specific flow of signal transduction perturbed by multiple single-nucleotide alterations
BackgroundIdentifying patient-specific flow of signal transduction perturbed by multiple single-nucleotide alterations is critical for improving...
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Viral Transduction of Mammalian Spermatogonial Stem Cells
Lentiviral vectors have been major tools for genetic manipulation of spermatogonial stem cells (SSCs) in vitro. Adeno-associated viral vectors are...
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GsPKS24, a calcineurin B-like protein-interacting protein kinase gene from Glycine soja, positively regulates tolerance to pH stress and ABA signal transduction
SOS2-like protein kinases ( PKS/CIPK ) family genes are known to be involved in various abiotic stresses in plants. Even though, its functions have...
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Single-Molecule Narrow-Field Microscopy of Protein-DNA Binding Dynamics in Glucose Signal Transduction of Live Yeast Cells
Single-molecule narrow-field microscopy is a versatile tool to investigate a diverse range of protein dynamics in live cells and has been extensively...